Chinese medicine treatment of gastroenterology becomes a joke.

Usually, the incidence of constipation is about 2-30%, and the elderly living in nursing homes increase to 50-70%; In the United States, an average of $250 million is invested in constipation treatment every year.

There are many treatments for constipation, and pharmacies also sell many constipation drugs. But we can still see a large number of constipation patients who are ineffective in treatment.

In clinical work, my major is gastroenterology. The research direction is functional gastrointestinal diseases and chronic liver diseases, and the doctoral research topic is the treatment of functional constipation.

In the process of investigation, I met a large number of constipation patients, some of whom were very stubborn, ranging from more than ten years to more than forty or fifty years of intractable constipation.

Early application of hemp seed to moisten intestines, angelica sinensis, Chinese medicine, lactulose, polyethylene glycol 4000, enzyme, inulin, small powder pills and other drugs can promote defecation. After long-term application, some patients are resistant to all drugs.

Drug resistance means that if you continue to use it, it will be ineffective. Then you need to increase the dose, and then increasing the dose is ineffective. It is very distressing for patients. Visit a famous doctor and try to improve the symptoms, but it is difficult.

Long-term constipation has caused many adverse effects. It has a bad influence on all the main systems of the body.

For the elderly, constipation can induce the attack of acute cardiovascular and cerebrovascular events, leading to angina pectoris, acute myocardial infarction and cerebral hemorrhage, which is caused by anger and responsibility when defecation is weak.

Why constipation can lead to cardiovascular events such as myocardial infarction?

The reason is that when forced defecation, it will cause the abdominal pressure to increase, increase the afterload of the heart, increase the work of the heart and accelerate the heart rate to meet the blood supply needs of the body. In this process, myocardial contractility is enhanced and oxygen consumption is increased. In those patients with coronary artery stenosis, vascular rupture is easy to occur. This is a very terrible and common cause of death.

It should be well understood that hemorrhoids bleeding caused by long-term constipation. The cause of hemorrhoids is also the result of poor defecation and forced contraction and extrusion of anus. However, hemorrhoids generally do not become malignant. More serious than hemorrhoids is that chronic constipation causes colon polyps.

Colonic polyp refers to the vegetation protruding from the epidermis of colonic mucosa and protruding into the cavity, which mostly occurs in sigmoid colon and rectum. The coarse fecal residues and foreign bodies in the intestine of constipation patients stimulate intestinal mucosal epithelium for a long time, causing rectal mucosal injury, cell dysplasia and polyp formation.

Now we have sufficient research to prove that 90% of colorectal cancer is transformed from intestinal polyps, specifically adenomas. This is also the bitter fruit of constipation.

There is a saying in China that there are ten men, nine hemorrhoids, ten women and ten hemorrhoids, which means the prevalence of hemorrhoids in the crowd is very, very high. Hemorrhoids often have anal pain and bloody stool when defecating. Constipation itself is also a major cause of hemorrhoids.

Constipation of stool blood type is often easily overlooked, thinking that it is just a hemorrhoid attack. In fact, constipation-induced colorectal polyps and colorectal tumors are characterized by blood at the initial onset, and there are no other special symptoms. Therefore, if you are a patient with constipation for many years, you must be alert to colon polyps and colon tumors. The best way is colonoscopy.

In addition to cardiovascular and cerebrovascular events, colon polyps, malignant tumors, constipation will also cause many other hazards. Such as skin deterioration, sleep disorder, sexual dysfunction, emotional abnormality and so on.

The large intestine is the lower segment of the digestive tract, about 1.5m long ... Traditional Chinese medicine describes the large intestine as six fu organs, which are transported but not hidden, so it is full but not solid. The function of the large intestine is to temporarily store and digest the remaining food residues and absorb the water in them. Food residue is fermented by bacteria and turned into feces. In addition to food residues, feces also include exfoliated intestinal epithelial cells and a large number of bacteria.

Because the pH and temperature in the large intestine are extremely conducive to the reproduction of bacteria, there will be more bacteria and decomposition products in the feces of constipation patients.

It is found that there are about 22 kinds of harmful substances in feces, including hydrogen sulfide, ammonia, biogas, carbon dioxide and other harmful gases and benzene, indole, botulinum toxin, botulinum toxin, muscarinic acid, cresol, butyric acid and so on. And some heavy metal salts harmful to human body.

There are a lot of catabolic products and harmful substances in feces. If it cannot be excreted in time, part of it can be absorbed through colon mucosa and enter the liver through portal vein system. On the one hand, it increases the burden on the liver, exhausts the liver detoxification enzyme system and damages the liver function; On the other hand, harmful substances entering the blood will cause damage to various systems of the human body.

We sometimes hear some swearing words, such as "shit in my head", which is of course a joke. Generally, there can't be shit in the brain, but metabolic waste can reach the brain through shit.

Modern research shows that the metabolites in feces can enter the brain through blood, which is the so-called brain-gut axis. In patients with long-term constipation, the tight connection between intestinal cells becomes loose, and toxins in the intestine are more likely to enter the body, causing chronic inflammation in the body. This seems to be more terrible than "taking a shit in your head"

For normal people, there should be defecation every day. This process is not only to complete a physiological task, but also to expel toxins and feel relaxed. Imagine how painful it is to run around with a few pounds of shit and not get rid of it. Personally, if I don't defecate for a day, the whole person will feel anxious and depressed in study and work.

Constipation patients may not be as sensitive as I am in the process of adapting to constipation. However, they must have an urgent desire to defecate and improve their inability to defecate.

Today's problem, the core of popular science lies in the harm of constipation. I also mentioned my doctoral research topic, which is the treatment of constipation. Here, together with Amway. Our project needs patients with Beijing medical insurance, aged between 18-70. Can't suffer from diabetes, thyroid diseases, etc. If you are interested in our project, please contact me. I'm Dr. Liu Xinyuan from the Department of Gastroenterology, China-Japan Friendship Hospital.

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