What medicine does depression take?

1. treatment target

The treatment of depressive episode should achieve three goals: ① to improve the clinical cure rate and minimize the disability rate and suicide rate, the key is to completely eliminate clinical symptoms; ② Improve the quality of life and restore social functions; ③ Prevention of recurrence.

2. Principles of treatment

① Individualized treatment; ② The dosage should be gradually increased, and the minimum effective dosage should be adopted as far as possible to minimize adverse reactions and improve medication compliance; ③ Full whole course treatment; ④ Single medication as far as possible. If the curative effect is not good, we can consider switching treatment, synergistic treatment or combined treatment, but we should pay attention to drug interaction. ⑤ Inform before treatment; ⑥ During the treatment, closely observe the changes of illness and adverse reactions, and handle them in time; ⑦ It can be combined with psychotherapy to increase the curative effect; ⑧ Actively treat other physical diseases, material dependence and anxiety. Related to depression.

3. Drug therapy

Drug therapy is the main treatment for moderate or above depressive episodes. At present, the first-line clinical antidepressants mainly include selective serotonin reuptake inhibitors (SSRI, representing drugs fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram and escitalopram), serotonin and norepinephrine reuptake inhibitors (SNRI, representing drugs venlafaxine and duloxetine), norepinephrine and specific serotonin antidepressants (NaSSA).

4. Psychotherapy

For depressive patients with obvious psychosocial factors, psychotherapy is often combined with medication. Commonly used psychotherapy methods include supportive psychotherapy, cognitive behavioral therapy, interpersonal therapy, marriage and family therapy, psychodynamic therapy and so on. Among them, the effect of cognitive behavioral therapy on depression has been recognized.

5. Physical therapy

Patients who have serious negative suicide attempts and patients who fail to respond to antidepressants can be treated with modified electroconvulsive therapy (MECT). Drug maintenance treatment is still needed after electroconvulsive therapy. In recent years, a new physical therapy-repetitive transcranial magnetic stimulation (rTMS) therapy has emerged, which is mainly suitable for mild to moderate depressive episodes.

prevent

Some people have followed up the patients with depression for 10 years, and found that 75% ~ 80% of the patients have recurred many times, so the patients with depression need preventive treatment. More than 3 episodes require long-term treatment or even lifelong medication. Most scholars believe that the dosage of maintenance drugs should be the same as that of treatment, and regular outpatient follow-up observation should be carried out. Psychotherapy and social support system also play a very important role in preventing the recurrence of this disease. We should try our best to reduce the patients' excessive psychological burden and pressure, help them solve practical difficulties and problems in life and work, improve their coping ability, actively create a good environment for them and prevent recurrence.