Can you spell American English in the college entrance examination English test?

Yes, you can. But you should pay attention to the unity of the whole article. You can't spell an article or a question in English and American at the same time. In fact, to tell the truth, there are no strict rules in the current college entrance examination. It is safer to look at the spelling recommended in your textbook. After all, the college entrance examination is a very important exam. To be on the safe side, you should write the most accurate one. American English is more casual and is loved by many young people, so it is not impossible to use it in the college entrance examination. It would be a joke to deduct the college entrance examination paper because the teacher can't recognize American spelling now.