What effect and harm does long-term drinking have on the body?

Interpersonal communication in modern society is inseparable from wine table culture. Many people like to talk about business, projects and contracts at the wine table.

There are quite a few people who drink for a long time, and most alcoholics only care about the refreshing pleasure they get in an instant, so they like to drink a lot and are used to numb themselves with alcohol, but they never pay attention to maintaining their health. Others will think that drinking has nothing to do with it and nothing will happen. When they realize the harm of alcohol, it is difficult for them to stop drinking, so they simply give up treatment. So, I want to remind those friends who haven't realized the harm of alcohol, don't have any unrealistic illusions about alcohol, and look at the impact of drinking on your health!

After drinking, 70% of the alcohol is mainly absorbed by the stomach, and the rest is absorbed by the small intestine. It begins to enter the blood after 2-5 minutes and reaches its peak after 30-90 minutes. More than 95% of the ingested ethanol is metabolized by the liver, mainly through the action of alcohol dehydrogenase and microsomal alcohol oxidase system in liver cells, which is dehydrogenated and oxidized into acetaldehyde, which is then dehydrogenated and oxidized into acetic acid, and finally produces carbon dioxide, water and heat.

Acetaldehyde has serious hepatotoxicity, which can make the membrane lipid of hepatocytes peroxidation, destroy the microtubule structure of hepatocytes, reduce the function of microtubules and damage mitochondria. It can promote the proliferation of hepatic interstitial fibrous tissue and cause the infiltration of inflammatory cells in the liver. The toxicity of acetic acid in vivo is 10 times that of ethanol, which is considered to be closely related to hepatotoxicity. After drinking, it first enters the stomach and then metabolizes in the liver. Alcohol is very harmful to the stomach and liver, which can lead to cirrhosis and malnutrition. Alcohol addiction is extremely harmful, the most direct and common of which is the damage to gastric mucosa.

So what diseases are more likely to be caused by long-term drinking? Next, let's take a look.

1, beer heart beer degree is the smallest among common wines, but if excessive drinking, the alcohol accumulated in the body will damage the liver function of the drinker, increase the burden on the kidney, and the myocardial tissue will also have fat cell infiltration, which will weaken the myocardial function and cause tachycardia. Supplementing too much liquid will increase blood circulation, increase the burden on the heart, easily lead to myocardial hypertrophy, ventricular volume expansion, forming a "beer heart", and also lead to heart failure, arrhythmia and other diseases.

2. Drinking a lot of beer belly for a long time will cause fat accumulation in the body, leading to paunch and forming a "beer belly", which will easily lead to an increase in blood lipids and blood pressure.

3, lead poisoning beer brewing raw materials contain lead, after drinking a lot, the blood lead content increases, which makes people's intelligence decline, slow response, and serious damage to the reproductive system; Old people are prone to Alzheimer's disease.

4, gastroenteritis, drinking a lot of beer, causing damage to the gastric mucosa, causing gastritis and peptic ulcer, and symptoms such as epigastric discomfort, loss of appetite, bloating, acid reflux.