What is the main reason for the increase of bacterial drug resistance?

The increase in drug resistance is mainly due to the long-term use of antibiotics.

Generally speaking, similar to human immunity to diseases, drug resistance is the "resistance" and "immunity" of pathogens to killing drugs, and this ability comes from drug resistance genes. With the use of antibiotics since World War II, especially the low-dose abuse of antibiotics, the drug resistance of pathogens has been greatly enhanced.

When antibiotics are used for a long time, most sensitive strains are constantly killed, and drug-resistant strains reproduce to replace sensitive strains, thus increasing the drug resistance rate of bacteria. This is the main reason for producing drug-resistant bacteria.

Extended data

Related reasons for the increase of drug resistance caused by long-term use of antibiotics;

1, China's medical system is not perfect.

2. Doctors' medication habits and medical technical level are not perfect. Any overtime, excessive, symptomatic or not strictly standardized use of antibiotics belongs to antibiotic abuse.

3. There are hundreds of pharmaceutical manufacturers that produce the same antibiotic, and there may be vicious competition in market sales, leading to unreasonable use of antibiotics.

4. The rapid application of antibiotics in aquaculture leads to antibiotics everywhere in the air and soil around farms, surface water and groundwater, and retail meat and poultry. These antibiotics can accumulate in the human body through various channels.

Baidu encyclopedia-drug resistance