What is the effect of selling "COVID-19 specific drugs" online? How much is the specific medicine in COVID-19?

Recently, some media reported that "COVID-19 specific drugs" have been sold on some Internet medical platforms in the form of online prescription drugs. In the face of epidemic situation, COVID-19's "vaccine+specific medicine" is considered as the last combined means of human epidemic prevention. The reporter interviewed several citizens who had bought COVID-19 oral medicine before, and got a detailed understanding of the use experience of the medicine.

Cough symptoms are relieved after taking it.

Miss Chen, who lives in Chengdu, told reporters that it was her husband who bought Pfizer oral drugs. He is currently working in the United States. After her husband was recently infected with COVID-19 virus, he developed symptoms of fever, headache and cough. After taking antipyretics at home, I went to the hospital. After consulting the doctor, he was given Pfizer's oral medicine. The doctor ordered him to take it twice a day for three days.

Photo courtesy of respondents

When she learned that the domestic price was 2980 yuan, she said that the price seemed to be cheaper than that in the United States. "My husband seems to need $530 to buy a box." She told reporters that after taking the medicine, his cough symptoms eased a lot and his body was still recovering. She said that doctors have repeatedly reminded that they must take it according to the doctor's advice, and it is not allowed to increase the dosage or the patient to buy the medicine himself.

Wang Guiqiang, director of the Department of Infectious Diseases of the First Hospital of Peking University, introduced that Pfizer's oral anti-COVID-19 drug Paciclovir て/Ritonavir tablets is a small molecule drug, belonging to a mixture and an oral drug. Drugs inhibit the protease level of the virus, block the virus replication cycle and reduce virus replication, thus resisting the virus through this link.

The reporter learned that on February 1 1 2022, the State Pharmaceutical Products Supervision and Administration conducted an emergency review and approval according to the relevant provisions of the Drug Administration Law and the Special Approval Procedure for Drugs, and conditionally approved the import registration of the combined packaging of Nimat Wei tablets and ritonavir tablets in COVID-19, Pfizer; /kloc-in March, 2005, National Health Commission issued the "Revised Essentials of novel coronavirus's Diagnosis and Treatment Plan", which showed that in March,/kloc-0, 2007, the State Administration of Pharmaceutical Products approved the floating of "simmering spoon" and "plutonium for record" of paciclovir tablets, and the first batch was 2.65438+.

At the press conference of the State Council Joint Prevention and Control Mechanism held on April 1, Wang Guiqiang said that the drug is suitable for light, common, heavy and high-risk groups. The use of these two drugs aims at early intervention, blocking the development of the disease and reducing the risk of severe illness and hospitalization. He stressed that the drug is only used in designated hospitals, and it needs to be used in strict accordance with the instructions under the guidance of a doctor to observe the effect. At the same time, we should observe the side effects and consider the interaction between small molecules of drugs.

Domestic COVID-19 oral medicine: "On the first day of entering the cabin, I ate Aftab."

So far, only two products have been approved as antiviral drugs in COVID-19, besides the Pfizer Nimavir Tablets/Ritonavir Tablets mentioned above, there are also alfredin tablets from real creatures.

Previously, A Fuding had been removed from the shelves after a short online sale. It is understood that AZF tablet is the only domestic COVID-19 oral drug approved for marketing in China, which is a product of Henan Ruier Biotechnology Co., Ltd. This drug was originally used to treat adult patients infected with HIV- 1 with high viral load. In July this year, it was approved for the treatment of ordinary adult patients in novel coronavirus. However, this new indication is conditionally approved, and patients should use drugs in strict accordance with the instructions under the guidance of doctors.

Miss Qiu, who lives in Zhengzhou, Henan Province, was listed as a secret contact in June 19 10 and was transferred to the isolation hotel. On June 2 1 day, after the nucleic acid test was positive, she was transferred to a local cabin. She introduced that on 2 1 that night, she was arranged to take three tablets of afudin and needed to take it on an empty stomach at night. She told reporters that her symptoms were mild, mainly manifested as cough and muscle aches, but because the nucleic acid result was always positive, it didn't turn negative until165438+1October 7.

Photos of instructions for taking afudin tablets were provided by the interviewees.

Another oral medicine imported from COVID-19: the price is nearly 5,000.

Mr. Xu, a native of Taiwan Province Province who works in Guangzhou, was unfortunately "recruited" by Taiwan Province Province when he returned to Taiwan Province Province for a holiday a while ago. "I have a splitting headache, like a big truck running over my head." He described himself as having obvious symptoms and feeling unwell that day. Knowing that COVID-19's oral medicine was sold in Taiwan Province, he inquired about it in many ways. Finally, he asked someone to buy 10 box of oral drug monapivoxil from Merck.

Photo courtesy of respondents

Monapivoxil is the first authorized oral anti-COVID-19 drug in the world, which belongs to a new ribonucleoside analog prodrug. It is used to treat adult patients with novel coronavirus test positive, diagnosed as mild to moderate COVID-19's disease and potentially serious risk.

Mr. Xu told reporters that he bought the medicine at a price of NT$ 20,000 per box. After taking it, the headache symptoms are slightly relieved, but it still takes about 5 days to "turn negative". The reporter learned through public information that a course of treatment for Merck in European and American markets costs 700 dollars, or 4,700 yuan.

What is the effect of specific drugs? Experts advise not to hoard medicine blindly.

In a previous media interview, Mei Tsinghua, director of the Pharmacy Department of the Second People's Hospital of Guangdong Province, said that there is no specific medicine in COVID-19 at present. At present, the two drugs collected in designated hospitals in Guangzhou can mainly prevent patients with mild and moderate symptoms from progressing to severe symptoms to some extent. As far as hospital equipment is concerned, these two drugs are enough. He appealed to people that the resources of any drug are limited. I am most afraid that everyone will rush to prepare medicines and use unnecessary medicines. If you take the medicine according to the doctor's advice, it will definitely be enough.

Du Nan Aoyi reporter Lin Shiyan