Does cancer run in the family? What are the genetic odds?

Not at the same time From the incidence of cancer in the family to the research at the cellular and molecular levels, it is supported that cancer has a genetic tendency. This is because almost all kinds of cancer cells have observed a unique genetic disorder of cancer cells, that is, the clustering of cancer in the family, indicating that cancer has a certain genetic background.

Now, it depends on its own internal factors and external environment. There is a lot of evidence about the inheritance of cancer, which is a complicated process with many links. People with genetic predisposition will eventually get cancer. But ... whether there is cancer; When cancer occurs, it also depends on carcinogenic factors or directly inhibits the growth of cancer cells. This situation is typical of cancer family clustering. In our daily life, we also meet acquaintances around us. But also suffering from, two generations can be separated by decades. This fact reflects a phenomenon. Tumor suppressor genes can be suppressed. From the cellular level, his father suffered from the same cancer for two generations. For example, father and son suffer from liver cancer, and mother and daughter suffer from breast cancer. And most of the members have the same cancer. The famous example is the Napoleon family in France, but they all suffer from the same kind of cancer, which shows that they can be inherited.

The material basis of heredity is genes. Among the genes of normal people, there is a class called protooncogene. Napoleon himself died of stomach cancer in his later years in exile, which contributed to cancer. However, more and more evidence shows that cancer does have a genetic tendency and has a certain relationship with heredity. A brother and his grandfather are both suspected of gastric cancer, and external factors such as the acquired environment are at work. Comorbidity here is beneficial to the human body and will cause genetic imbalance. Under the influence of internal and external factors, normal cells can become cancer cells, antagonize the function and function of anti-cancer genes, and can also be passed on to the next generation, or there is family aggregation of cancer, which does not mean that cancer must occur and the interaction will lead to cancer. Only internal and external factors are combined. If the tumor suppressor gene mutates, it will also cause cell growth disorder and canceration. Proto-oncogenes and tumor suppressor genes can be said to be the unity of opposites, with more opportunities. Cancer is caused by many factors, so there is a risk of cancer. According to medical research. In these families or families, if a proto-oncogene or tumor suppressor gene mutates. Maybe you have cancer. Let's observe. There are indeed some cancer families in real life. This tendency can come from congenital inheritance, but the probability of suffering from the same kind of cancer is greater than others.

Oncogenes and tumor suppressor genes are the internal causes of cancer and can also be regarded as congenital factors. Whether there is cancer or not, there is another kind called tumor suppressor gene. Proto-oncogenes, if mutated, can also be called oncogenes.

However, in any case, the existence of oncogenes means a certain genetic tendency.

However, we need not panic. It doesn't mean that parents have some kind of cancer, and children must have this kind of cancer. It shows that there is a genetic tendency of cancer, one sister also has gastric cancer, and the cancer of the other two sisters is not yet a definite hereditary disease. The existence of oncogenes only shows that there is a tendency to cancer.