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Blush after drinking
Let's talk about the reason for blushing first. Many people think that it is caused by alcohol, but it is not. It's caused by acetaldehyde. Acetaldehyde can dilate capillaries, and the dilation of facial capillaries is the cause of blushing. Therefore, people who blush after drinking alcohol show that they can quickly convert ethanol into acetaldehyde, indicating that they have efficient alcohol dehydrogenase in their bodies. But don't forget that there is another enzyme, acetaldehyde dehydrogenase. People who blush after drinking only have the former enzyme but not the latter, so acetaldehyde accumulates rapidly in the body and cannot be metabolized, so their faces turn red for a long time. However, everyone has experience. 1-2 hours later, the red color will gradually disappear. This is because P450 in the liver slowly converts acetaldehyde into acetic acid, and then enters the TCA cycle and is metabolized.
What about people who drink too much? These people tend to get whiter and whiter, and at some point they suddenly fail and get drunk. That's because these people don't have high-activity alcohol dehydrogenase and acetaldehyde dehydrogenase, and mainly rely on the slow oxidation of P450 in the liver (because P450 is a group of oxidases with low specificity). So, why does such a person give people the feeling that they can drink? At that time, because they diluted alcohol with body fluids, the older they were, the more they felt they could drink. In general, when the alcohol concentration exceeds 0. 1%, they will be in a coma. For most southerners, it is half a catty of white wine, while northerners can drink 8 liang to 1 catty of white wine because of their big size. But no matter who it is, if the face is getting whiter and whiter, it is best not to exceed half a catty, otherwise there may be acute alcoholism.
What if a person has both highly active alcohol dehydrogenase and highly active acetaldehyde dehydrogenase? He/she is the legendary wine basket. How to judge whether he/she is a wine basket? See if you are sweating like a pig. Because if these two enzymes have high activity, alcohol will quickly turn into acetic acid and enter TCA cycle to generate heat, so a lot of heat will cause sweating. You can only admit that you are unlucky when you meet such a person, even ten or eight normal people can't beat him. Fortunately, there are not many such people, about 65438+ one in ten thousand.
One thing to remind everyone is that people who blush after drinking are not easy to hurt their liver, while people with pale wine are particularly easy to hurt their liver. Red-faced people generally don't give up drinking, so they drink less and get sleepy after drinking. After sleeping for 15-30 minutes, they will be full of energy again. People with white faces often don't know their bottom line and drink too much in high excitement until they get drunk. The alcohol in their bodies accumulates without the treatment of highly active enzymes, which leads to liver damage. Alcoholic liver injury generally only occurs in these people. Red-faced people can drink even if they vomit several times in a row, while white-faced people need more time to rest, because the metabolism of alcohol takes a day or two.
By the way, according to relevant research, people in Jiangsu and Zhejiang provinces (descendants of the ancient State of Wu and the State of Yue) seem to be the origin of the blush gene, which means that most of these people carry highly active alcohol dehydrogenase. Most northerners are white faces. So if you were born in the north and your face is red, what does it mean? The answer is obvious, because the red face gene is a dominant gene.
Drink plenty of boiled water when drinking (it is also a kind of water mixed in wine, hehe), and never drink tea water.
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The blood vessels of the human body are dominated by two kinds of nerves, one is called sympathetic nerve, which can promote vasodilation when excited; The other is called parasympathetic nerve, which can make blood vessels contract when excited and dilate when inhibited. Usually, these two nerves coordinate with each other to control the contraction and expansion of blood vessels. Alcohol can excite sympathetic nerve, inhibit parasympathetic nerve, and make blood vessels expand greatly than usual. Facial skin is thin and there are many capillaries, so people will turn red after drinking.
Why do some people blush and others turn pale when drinking?
Let's talk about the reason for blushing first. Many people think that it is caused by alcohol, but it is not. It's caused by acetaldehyde. Acetaldehyde can dilate capillaries, and the dilation of facial capillaries is the cause of blushing. Therefore, people who blush after drinking alcohol show that they can quickly convert ethanol into acetaldehyde, indicating that they have efficient alcohol dehydrogenase in their bodies. But don't forget that there is another enzyme, acetaldehyde dehydrogenase. People who blush after drinking only have the former enzyme but not the latter, so acetaldehyde accumulates rapidly in the body and cannot be metabolized, so their faces turn red for a long time. However, everyone has experience. 1-2 hours later, the red color will gradually disappear. This is because P450 in the liver slowly converts acetaldehyde into acetic acid, and then enters the TCA cycle and is metabolized.
What about people who drink too much? These people tend to get whiter and whiter, and at some point they suddenly fail and get drunk. That's because these people don't have high-activity alcohol dehydrogenase and acetaldehyde dehydrogenase, and mainly rely on the slow oxidation of P450 in the liver (because P450 is a group of oxidases with low specificity). So, why does such a person give people the feeling that they can drink? At that time, because they diluted alcohol with body fluids, the older they were, the more they felt they could drink. In general, when the alcohol concentration exceeds 0. 1%, they will be in a coma. For most southerners, it is half a catty of white wine, while northerners can drink 8 liang to 1 catty of white wine because of their big size. But no matter who it is, if the face is getting whiter and whiter, it is best not to exceed half a catty, otherwise there may be acute alcoholism.
What if a person has both highly active alcohol dehydrogenase and highly active acetaldehyde dehydrogenase? He/she is the legendary wine basket. How to judge whether he/she is a wine basket? See if you are sweating like a pig. Because if these two enzymes have high activity, alcohol will quickly turn into acetic acid and enter TCA cycle to generate heat, so a lot of heat will cause sweating. You can only admit that you are unlucky when you meet such a person, even ten or eight normal people can't beat him. Fortunately, there are not many such people, about 65438+ one in ten thousand.
One thing to remind everyone is that people who blush after drinking are not easy to hurt their liver, while people with pale wine are particularly easy to hurt their liver. Red-faced people generally don't give up drinking, so they drink less and get sleepy after drinking. After sleeping for 15-30 minutes, they will be full of energy again. People with white faces often don't know their bottom line and drink too much in high excitement until they get drunk. The alcohol in their bodies accumulates without the treatment of highly active enzymes, which leads to liver damage. Alcoholic liver injury generally only occurs in these people. Red-faced people can drink even if they vomit several times in a row, while white-faced people need more time to rest, because the metabolism of alcohol takes a day or two.
By the way, according to relevant research, people in Jiangsu and Zhejiang provinces (descendants of the ancient State of Wu and the State of Yue) seem to be the origin of the blush gene, which means that most of these people carry highly active alcohol dehydrogenase. Most northerners are white faces. So if you were born in the north and your face is red, what does it mean? The answer is obvious, because the red face gene is a dominant gene. Many people turn red after drinking, which is the result of alcohol acting on the central nervous system.
After drinking, the stomach will absorb some alcohol, and the liver can also metabolize and filter some. Excessive drinking exceeds the digestive capacity of the stomach and the metabolic capacity of the liver. Residual alcohol flows into the brain with blood, and the normal function of brain cells has changed, thus promoting the expansion of facial subcutaneous blood vessels, increasing blood volume and turning red. If you continue to drink when you are blushing, your heart will speed up, your blood vessels will expand and your blood pressure will drop. In order to ensure the blood supply to the main organs in your body, you must shrink the capillaries and raise your blood pressure. Therefore, the blood flow around the face is blocked, the blood volume is reduced, and the face is blue.
For people who drink a lot, blood vessels are constantly expanding and contracting. With the passage of time, blood vessels will become very fragile, and facial capillaries may rupture, resulting in little red dot on the skin. For example, rosacea is a chronic skin disease caused by long-term expansion of local blood vessels, which has a lot to do with alcoholism.
Residual alcohol in blood will lead to changes in brain function and also affect human muscle activity. So drunken people walk unsteadily and speak vaguely.
If you drink with empty clothes, alcohol will have a greater impact on the human body, because there is nothing in your stomach to dilute alcohol at this time, resulting in more alcohol flowing from your blood to your brain.
The effect of alcohol will also increase the secretion of adrenaline, make the central blood vessels contract and raise blood pressure. So alcoholism can also induce hypertension.
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