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At the end of the Qing Dynasty, Xilaile, a village doctor in Cangzhou, often used strange methods to cure diseases and save lives, which was uncontroversial. Princess Gege of King Jing of Beijing was seriously ill and was declared terminally ill by doctor Wang Tianhe. Lu Zhengming, a close friend of King Jing, brought Xilaile to the capital to treat Princess Gege, and Xilaile used naked fumigation bath to save Princess Gege, which won the praise of King Jing, but caused the jealousy of doctor Wang's teeth, so he tried every means to treat her. Xilaile was already in love with her lover who opened a restaurant in Cangzhou.

Sai Xishi, a beautiful young widow, was even more reluctant to entangle herself with Doctor Wang in this troubled place in Beijing. He refused to stay in Beijing several times, but Jing Wangye and Lu Zhengming finally managed to keep him in Beijing and moved his "Yixiaotang" in Cangzhou to Beijing for business. In Beijing, firstly, Xilaile repeatedly cured all kinds of patients' incurable diseases with strange remedies, which opened the eyes of the people in Beijing and won the reputation of an imperial doctor. Later, he went to the palace to show Zhenfei the stick injury with a wonderful prescription and gained the appreciation of the emperor. This makes it even more difficult for Doctor Wang, who is jealous of the virtuous and talented, to sleep and sleep. He sent someone to burn down the newly built "Yixiaotang". I heard that Hilale was buried in the sea of fire, and Wang Tianhe could not help but suffer from his own conscience and kneel before the Bodhisattva to repent. Unexpectedly, Xilaile escaped from the fire by mistake, and Wang Tianhe was more and more eager to kill her heart. She repeatedly framed Xilaile in front of Empress Dowager Cixi. Xilaile had to compete with Wang Tianhe again and again. Although he dodged Wang Tianhe's plot again and again with his unique cunning, he was still distressed. He was also a medical practitioner. Why did he fight so hard?

In order to let Xilaile stay in the capital to see a doctor for himself, King Jing had Sai Xishi's restaurant "food is the sky" moved to the opposite side of the "Yixiaotang" in the capital, which made his wife Hu, who was jealous of Sai Xishi, very upset. She tried all kinds of tricks to rectify Xilaile, who was in love with her husband. When she was sick, Xilaile was full of wonderful ideas, but there was nothing she could do in front of Hu.

Smith, a German doctor who had been dismissive of Chinese medicine, was dumbfounded when he saw Hilale's strange but miraculous treatment. And Hilale was stunned when he saw Smith with a knife, scissors, saw pliers to cut open his belly. In this case, two practitioners in China, one in the west and the other in the west became friends. Later, when Hilale was in a desperate situation, Smith really saved his life ...

Although Hilale was a country doctor, he was also a risk-averse who worried about the country and the people. He hated the Japanese for killing so many China people in the Sino-Japanese War of 1894-1895, and the Japanese minister. Nave Li Hongzhang looked for him to see a doctor, but he just signed the "treaty of shimonoseki", and Li Hongzhang, who ceded Taiwan Province, was really sarcastic, which provoked Li Hongzhang's great anger and almost killed him ... < P > The apprentice of Hilale, Defu, was white in front of a good girl, so he ran around Qianmen Street wearing a yellow jacket that the emperor gave to his master, and Wang Tianhe made use of the topic to put Hilale and his disciples on death row for deceiving the monarch. Hu, who was in a panic, had to consult with Sai Xishi about the rescue. Sai Xishi ventured into the Shuntianfu Prison, which moved Xilaile to tears. He vowed that as long as he could get out alive, he would immediately marry Sai Xishi and welcome him home as his concubine. Later, Sai Xishi broke into the lobby of punishments, and Tian Kui, who was rescued by Xilaile in Cangzhou in his early years and later became an official in punishments, rescued Xilaile. However, as soon as she arrived at Hu's house, Hilale never dared to talk about marrying Sishi as a concubine, which made Sishi, who was full of hope, very sad. Tian Kui, who is interested in Sai Xishi, courted Sai Xishi, and Sai Xishi said in anger that he would marry Tian Kui. He was so anxious that he was tickled with joy. Jing Wang Ye stepped forward as a matchmaker and ordered Hu to agree to take Xi Xi Le as his concubine. Unexpectedly, Hu would rather die than accept it, and Jing Wang Ye learned Hu's interests and retreated in confusion. In a rage, Sishi closed the restaurant and made a lifelong engagement with Tian Kui. Hilaire was greatly lost and sad.

In the midsummer, there was a plague in Cangzhou, and a large number of victims died of illness. The court sent Doctor Wang as an imperial envoy to supervise it. Doctor Wang colluded with Meng Qinghe, a drug tyrant in Cangzhou, embezzled medicine silver and bought inferior herbs. In addition, the victims wandered around, and the plague disappeared in the east and rose in the west, which could not be repeated for a long time. Xilaile went to Cangzhou with King Jing. He used the method of soaking herbs in wells. No matter where the victims wandered, they had to drink water. As long as they drank well water, they could cure the disease, and the plague was quickly controlled. Doctor Wang felt worse than himself, and his jealousy became more and more intense.

The Reform Movement of 1898 failed. As a friend of the Reform Movement, Lu Zhengming attempted suicide and was dying. The imperial court ordered Xilaile to save Lu Zhengming in order to trace his comrades. Lu Zhengming was afraid that he could not stand the torture and dug up the King Jing who secretly supported the Reform Movement, and begged Xilaile to kill himself. Xilaile was caught in extreme contradictions. He finally gave Lu Zhengming a dead medicine, and was immediately accused by Doctor Wang of being a political disorder. In order to please Empress Cinuo and Doctor Wang, Tian Kui decided to betray his savior and sentenced Xilaile to death. Sai Xishi, who was ready to hold a wedding ceremony with Tian Kui, angrily denounced Tian Kui's ingratitude and left him for Cangzhou. At the critical moment, Hu blamed himself for poisoning Lu Zhengming, and went to Jiuquan for Hilale. Before she died, she entrusted her husband and all her possessions to Sai Xishi ...

In the early years of the Republic of China, Hilale and Sai Xishi, who were sent to Heilongjiang, returned to the capital after more than ten years' absence. Wang Tianhe, an old man, was dying of a strange disease. Lu Zhongken, who accompanied Wang Tianhe for decades, begged Xilaile to save his life. Out of benevolence and righteousness, Xilaile wrote a life-saving prescription for Wang Tianhe with complicated feelings. However, when Wang Tianhe knew that it was the medicine prescribed by Xilaile, he had no face to swallow the life-saving medicine of Xilaile, which had been hunted down and framed by himself for decades, knocked the medicine jar to the ground and died in shame and anger. "Yixiaotang" and "Food is the Sky" reopened, and their business was booming. After suffering, Hilale and Cecily showed their heartfelt smiles.

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