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Antiviral treatment of hepatitis B
Advantages and disadvantages of antiviral treatment for hepatitis B
Hepatitis B virus is a common treatment method, so what are the advantages and disadvantages of hepatitis B virus treatment?
Antiviral therapy has two advantages in the treatment of hepatitis B:
On the one hand, chronic hepatitis B virus is the most important factor of virus activity;
On the other hand, it is very important that people with high virus are prone to cirrhosis and liver cancer. After antiviral treatment and long-term virus control, this kind of patients will reduce the chances of cirrhosis and liver cancer, which has been confirmed in the clinical treatment of patients in the past. It is also found in clinical research that it is very important to control the virus for a long time.
Interferon needs subcutaneous injection during use. Ordinary interferon is injected three times a week during use, and once a week if patients use long-acting interferon. The side effects of interferon are also very obvious, including flu-like symptoms and decreased peripheral blood picture.
How long does it take for hepatitis B antiviral treatment?
Hepatitis B antiviral treatment needs a cycle, usually how long does it take?
There is no definite treatment time for hepatitis B antiviral therapy, but there are certain treatment goals. One is normal liver function, one is negative for serum virus, and the third is negative for E antigen. These three indicators are the end point of treatment. In order to prevent recurrence, it is necessary to continue taking the drug for 9 to 12 months after reaching these three goals, and observe it regularly every 3 months.
At present, the most effective measure for hepatitis B in clinical medicine is antiviral therapy, because there is no specific medicine to completely eliminate hepatitis B virus, and only taking antiviral drugs can control the development of hepatitis B virus and reduce its infectivity. However, how long it takes to treat hepatitis B virus depends on the patient's condition. But generally speaking, it takes a long time to take medicine to reduce the infectivity of the virus.
The best time for antiviral treatment of hepatitis B
The sooner the antiviral treatment for hepatitis B, the better. When is the best time for antiviral treatment of hepatitis B?
Hepatitis B is usually treated with antiviral therapy, and its indications are mainly determined according to the levels of serum HBV DNA, serum ALT and the severity of liver diseases. At the same time, combined with the patient's age, family history, accompanying diseases and other factors, after comprehensively evaluating the risk of disease progression, decide whether to start antiviral treatment. Dynamic evaluation has more clinical significance than single detection. For HBeAg positive patients, it is recommended to observe for 3-6 months after the ALT level rises. If there is no spontaneous HBeAg seroconversion, it is recommended to consider antiviral treatment.
Antiviral treatment of hepatitis B is an important part of hepatitis B treatment. When chronic hepatitis B patients or hepatitis B virus carriers have persistent or repeated abnormal liver function, mainly when alanine aminotransferase rises to more than twice the upper limit of normal value, antiviral treatment should be carried out.
Indications for antiviral treatment of hepatitis B
There are certain standards for antiviral treatment of hepatitis B, so what are the indications for antiviral treatment of hepatitis B?
The indications of antiviral therapy for hepatitis B can be summarized as follows: As long as hepatitis B is in active period, antiviral therapy is needed. After hepatitis B virus infection, it can be manifested in many different disease states, among which hepatitis B virus carriers or active hepatitis B are more common. Only active hepatitis B can cause inflammatory damage and fibrosis of the liver, so antiviral treatment is needed.
China's hepatitis B related guidelines clearly stipulate the indications for antiviral treatment: for patients with big three positive diseases, alanine aminotransferase reaches more than twice the upper limit of normal value, and the virus amount is greater than the sixth power of 10, so antiviral treatment is needed; For Xiao Sanyang, alanine aminotransferase is more than twice the upper limit of normal value, and the virus amount is more than the fifth power of 10, which requires antiviral treatment; For hepatitis B cirrhosis, no matter what the liver function is, as long as the virus amount is positive, antiviral treatment is needed.
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