My friend was amputated in a car accident and wanted to go to the hospital at the weekend. How to comfort him?

It's best not to say too much about this situation. The lowest and most inferior stage of life is to feel that the whole world is laughing at him and abandoning him. You are not a psychologist. All you have to do is say XX, and I'll come to you, so you can accommodate him to talk about whatever he wants. Stop talking about you. Time is the best medicine to cure. After a while, your friends will get better and bless you.