How long after operation is the best time for radiotherapy and chemotherapy, chemotherapy or radiotherapy first?

Chemotherapy is divided into combined chemotherapy and single chemotherapy. It is often interpreted as simple chemotherapy, while combined chemotherapy refers to the combination of surgery and radiotherapy to achieve the purpose of eliminating tumor cells. This kind of surgery combined with chemotherapy is also divided into preoperative chemotherapy and postoperative chemotherapy. Today, we will talk about the difference between the two. Is chemotherapy good before operation or after operation?

Preoperative chemotherapy

Let's start with preoperative chemotherapy. Before 1980s, amputation was the only treatment for malignant tumors of bone and soft tissue, and the 5-year survival rate of patients was only about 20%. However, in the past 30 years, the 5-year survival rate of patients has increased to 60%~70%, which is largely due to the development of chemotherapy technology in addition to the progress of surgical technology. For malignant tumors of bone and soft tissue, chemotherapy-surgery-chemotherapy is usually used in clinic. Preoperative chemotherapy, medically known as neoadjuvant chemotherapy, has the following functions: 1. Reduce the tumor volume, create conditions for surgery and improve the resection rate; 2. Kill most tumor cells and reduce the chance of tumor cells spreading during operation; 3. Kill tiny tumor cells in the distance; 4. Improve the success rate of limb salvage surgery and reduce the recurrence (if the patient goes to the hospital too late and has lost the opportunity of limb salvage, there is no need for preoperative chemotherapy)

Postoperative chemotherapy

Postoperative chemotherapy is mainly to completely kill those tumor cells, and postoperative chemotherapy is mainly to completely kill those tumor cells, because some tumor cells will inevitably not be cleaned up after surgery, and can only be completely cleaned up through chemotherapy. Without chemotherapy, the probability of occurrence is higher and the probability of recurrence is higher.

In fact, preoperative chemotherapy and postoperative chemotherapy bring the same pain to patients. Chemotherapy is to send chemotherapy drugs into the body by injection or oral administration, which will bring stimulation to the gastrointestinal system, so there will be symptoms such as vomiting and diarrhea during chemotherapy. Because chemotherapy drugs are not specific, they can kill tumor cells and cause damage to normal cells, so abnormal hemogram and fever will occur. Therefore, it is suggested that chemotherapy should be supplemented with Shenbaiyi, which can reduce the side effects of chemotherapy by increasing white blood cells, inhibiting chemotherapy vomiting, improving appetite and enhancing patients' immunity. Of course, you also need corresponding diet care.