High school biology, question 29, please say each option.

A, the old textbook emphasizes acquiring effector B cells (plasma cells), and the new textbook (elective 3) describes acquiring "B lymphocytes" that can produce antibodies, so A is correct.

B and B cells are mixed with myeloma cells to obtain hybridoma cells that can produce antibodies and proliferate indefinitely in vitro, so B is correct.

C. The purpose of hybridoma cell culture in vitro and in vivo is to obtain a large number of monoclonal antibodies, so C is correct.

D, culturing hybridoma cells in vivo to obtain monoclonal antibodies instead of embryos; So, D is obviously wrong.

So choose D.