In this way, aspirin can prevent thrombosis and myocardial infarction, while paying attention to side effects.

Friends with cardiovascular and cerebrovascular diseases will definitely be familiar with aspirin, because aspirin is the most basic drug for ischemic cardiovascular and cerebrovascular diseases.

We have all heard of acute myocardial infarction and acute cerebral infarction. In fact, the essence of these two critical diseases is caused by thrombus blocking blood vessels. Let me briefly talk about how blood clots are formed.

For various reasons, such as heredity, unhealthy diet, obesity, sedentary, uncontrolled three highs and so on, vascular garbage will accumulate in blood vessels, which is what we call atherosclerosis. These vascular wastes are constantly piled up on the inner wall of blood vessels and wrapped by the inner wall of blood vessels. With the increase of garbage. One day, this plaque wrapped in blood vessels may not be wrapped. Under some stimulation, the inner wall of blood vessels may rupture, resulting in plaque rupture, which may lead to bleeding.

After human bleeding, the hemostasis mechanism will be started immediately, and platelet aggregation plays an important role in the hemostasis process. After platelets participate in hemostasis, the ruptured plaque will begin to coagulate and form a blood clot, which is called intravascular thrombosis. This is the process of thrombosis. Once a thrombus is formed, blood vessels may be blocked. Obstruction in cardiovascular system is called myocardial infarction, and obstruction in cerebrovascular system is called cerebral infarction.

Just now we said that platelet aggregation was involved in thrombosis, so we tried to stop platelet aggregation, didn't we stop thrombosis? Aspirin is an anti-platelet aggregation drug, which is the antithrombotic effect of aspirin.

Some people say that aspirin is not a medicine for fever, pain and arthritis. Yes, this aspirin and aspirin for preventing thrombosis are both aspirin, but the difference is that different doses of aspirin have different effects.

100 years ago, aspirin was mainly used to treat arthritis, which required taking a large dose of aspirin, that is, taking more than 4000mg of aspirin every day, which had anti-inflammatory and anti-rheumatic effects. Later, it was found that moderate dose of aspirin, that is, 500 ~ 3000 mg/day, has antipyretic and analgesic effects, and is often used to treat fever, headache, toothache, neuralgia and muscle pain caused by colds.

Later, it was found that low-dose aspirin, 75~300 mg/ day, has anti-platelet aggregation effect and can be used to prevent cardiovascular and cerebrovascular thrombotic diseases. So at present, we suggest that aspirin 100mg should be given once a day for ischemic cardiovascular and cerebrovascular diseases.

At present, there are three main forms of aspirin: ordinary aspirin 25mg, enteric-coated aspirin 100mg and aspirin effervescent tablets. Enteric-coated tablets 100mg is an acid-resistant protective layer coated with common aspirin. Insoluble in acid environment in stomach, but only soluble in alkaline environment in intestine can significantly reduce its gastrointestinal side effects. It is the best dosage form for long-term use and should be taken on an empty stomach.

The mid-term results show that aspirin can reduce the risk of myocardial infarction by 44%, the incidence of the first fatal myocardial infarction by 66%, the incidence of the first myocardial infarction by 665,438+0% and the incidence of the first cerebral infarction by 58%.

Therefore, to prevent thrombosis, it is necessary to take aspirin orally for a long time, about 100mg, but it must be taken under the guidance of a doctor because aspirin has side effects.

1, the most common gastrointestinal symptoms: gastrointestinal symptoms are the most common adverse reactions of aspirin, and the more common symptoms are nausea, vomiting, epigastric discomfort or pain. Oral aspirin can directly stimulate gastric mucosa, causing epigastric discomfort, nausea and vomiting, and even gastrointestinal bleeding. Therefore, it is necessary to observe whether the stool color turns black for a long time. If yes, please seek medical attention in time.

2, nephrotoxicity: aspirin can cause hematuria nitrogen and blood creatinine to increase.

3, blood system damage: aspirin can inhibit platelets, so that coagulation factors are not easy to release, thus prolonging the bleeding time. The above blood injuries can be manifested as external manifestations such as ecchymosis of limbs, bleeding gums and nosebleeds. Observe the whole body appearance and check the blood routine regularly.

4. Allergic reaction: About two thousandths of patients may have asthma, urticaria, angioneurotic edema or shock. Patients who have difficulty breathing after taking aspirin are generally called aspirin asthma.

Aspirin is the basic medicine for friends who prevent thrombosis. Everyone needs to understand that aspirin is not used to relieve angina pectoris or improve symptoms. Simply put, it doesn't mean you have angina pectoris. If you take aspirin, you won't have it. The role of aspirin is to prevent further stenosis of blood vessels, angina pectoris, myocardial infarction and cerebral infarction.

Aspirin is the basic drug for thrombosis treatment. After decades of experiments with a large number of clinical data, it is still the pillar to prevent thrombosis!

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