What's the next jingle of Cefalgar wine?

Cephalosporin with wine, the next sentence says go.

"Cephalosporin with wine, leave when you say it." Everyone is familiar with this jingle, but few people know why cephalosporin and wine can't be taken together, and some even don't think so. They think they have a special constitution and it's okay to drink it.

In fact, the reason why cephalosporins can't be taken with wine is because they will have a disulfiram-like reaction, which is usually called the sulfur-like reaction of abstinence. Disulfiram is an anti-alcoholism drug, and drinking alcohol after taking it will cause serious discomfort, thus achieving the purpose of abstinence.

How long is it safe between cephalosporin and wine?

Since cephalosporin and wine can't be taken together, how long can the interval between them ensure safety? This problem needs to be viewed in two ways.

Cephalosporin can inhibit the activity of acetaldehyde dehydrogenase, and the inhibited acetaldehyde dehydrogenase takes 4~5 days to recover. Therefore, for the sake of safety, it is best to take cephalosporin for 7 days before drinking, or eat alcoholic foods and drugs, such as alcoholic chocolate, drunken crab, Huoxiang Zhengqi water and so on.

It is found that a healthy adult weighing 70 kg can handle 7 grams of pure alcohol in 1 hour, but the enzymes that metabolize alcohol in the body are limited. The oxidative metabolism of adult males who deal with alcohol day and night is limited to 8 bottles of beer with a capacity of 633 ml. If you drink three bottles of beer in a row within 1 hour, it will take about 9 hours for the influence of alcohol to disappear completely, even for people who drink a lot, it will take 6~9 hours.