What is erythema wave wound?

Lupus Erythematosus is an autoimmune disease, with slow onset, hidden onset and diverse clinical manifestations. The disease can involve many systems and organs of the body, and many autoantibodies can be found in the blood and organs of patients. Lupus erythematosus is an autoimmune disease, belonging to connective tissue diseases, which can be divided into discoid lupus erythematosus (DLE), systemic lupus erythematosus (SLE), subacute cutaneous lupus erythematosus and deep lupus erythematosus. Diagnostic criteria of lupus erythematosus in China

1. Butterfly erythema or discoid erythema: flat or fixed erythema appears on the neck, which usually does not involve nasolabial groove and discoid erythema. The raised erythema is covered with horny scales and hair follicle damage, and skin atrophy may occur in the focus.

2. Photosensitive X 10'/L or hemolytic anemia: skin allergy caused by sunlight.

3. Oral mucosal ulcer: painless ulcer in oral cavity or nasopharynx.

4. Non-deformed arthritis or multi-joint pain: Non-erosive arthritis involving two or more peripheral joints, characterized by joint swelling, pain or exudation.

5. Pleurisy or pericarditis: chest pain, pleural friction or pleural effusion; Pericarditis, abnormal electrocardiogram, pericardial fricative sound or pericardial effusion

6. Epilepsy or mental symptoms: non-drug or metabolic disorder, such as uremia, ketoacidosis or electrolyte disorder; Psychosis: Non-drug or metabolic disorder, such as uremia, ketoacidosis or electrolyte disorder.

7. proteinuria, tubular urine or hematuria: proteinuria >; 0.5g/dl or 3+; Cell casts can be red blood cells, hemoglobin, granular casts or mixed casts.

8. White blood cells are less than 4x 10'/L or platelets are less than 100.

9. Fluorescent antinuclear antibody is positive.

10. Anti-double-stranded DNA antibody positive or lupus cell positive.

1 1. Anti-Sm antibody is positive.

12.o decrease

13. Skin lupus band test (non-lesion site) was positive or renal biopsy was positive.

Those who meet any four of the above 13 can be diagnosed as lupus erythematosus.

Discoid lupus erythematosus: it mainly invades the skin and is the lightest type of lupus erythematosus. A few cases may have mild visceral damage, and a few cases (about 5%) may turn into systemic lupus erythematosus. At the initial stage of skin injury, there are one or several bright red spots, ranging in size from mung beans to soybeans, with scales attached to the surface, and then gradually expanding, showing a round or irregular shape, and the edge pigment is obviously deepened, slightly higher than the center. The center is pale, atrophic and low-lying, and the whole lesion is discoid (hence the name discoid lupus erythematosus). The damage is mainly distributed in sun-exposed parts, such as face, helix and scalp, and a few can involve upper chest, back of hand, forearm, lips and oral mucosa. Most patients have no symptoms, but it is difficult to completely disappear. The new injuries can be gradually increased or unchanged for many years, and the injuries are symmetrically distributed, or they can be merged into blocks, and the injuries in the middle part of the face can be merged into butterflies. Discoid lesions worsen after sun exposure or fatigue. Damage to the scalp can lead to permanent hair loss. Old injuries occasionally develop into squamous cell carcinoma of the skin.

Deep lupus erythematosus, also known as lupus panniculitis, is also the intermediate type of lupus erythematosus. Skin lesions are nodules or plaques, located in deep dermis or subcutaneous adipose tissue, with uncertain size and quantity, normal or reddish skin color, solid texture and no activity. Injuries can occur anywhere, the most common are cheeks, hips, arms, followed by calves and chest. After chronic treatment, it can last for several months to several years, leaving skin atrophy and depression after healing. Deep lupus erythematosus is unstable and can exist alone, and then it can be transformed into discoid lupus erythematosus, systemic lupus erythematosus or both.

Systemic lupus erythematosus is the most serious type of lupus erythematosus. The vast majority of patients have multiple system damage at the onset, and a few patients develop from other types of lupus erythematosus. Some patients are accompanied by other connective tissue diseases, such as scleroderma, dermatomyositis, Sjogren's syndrome, etc., forming various overlapping syndromes. The clinical manifestations of systemic lupus erythematosus are diverse and complicated, and most of them are severe, which may endanger the lives of patients due to lupus nephritis, lupus encephalopathy and the side effects of long-term large-scale medication.