What are the early symptoms of diabetic nephropathy? Can you sum it up for me?

First, proteinuria This is the first sign of diabetic nephropathy. When persistent proteinuria occurs, the glomerular filtration rate begins to decrease. With the development of the disease, the amount of urinary protein gradually increased, which was consistent with the severity of renal lesions. When the glomerular filtration rate is significantly lower than normal, a large amount of proteinuria can rapidly develop into renal failure. If the 24-hour urinary protein is less than 3 grams, and the amount of urinary protein does not increase significantly, the progress of renal failure will become slow. 2. About half of the patients with edema and nephrotic syndrome have edema, which may be hypoproteinemia caused by a large number of protein loss in urine, but the older they are, the more edema caused by other reasons, and about 20% of patients will have nephrotic syndrome. Third, hypertension Hypertension Because aldosterone, a substance that constricts blood vessels, is produced in the kidney, when the kidney is sick, the increase of aldosterone will cause uncontrollable hypertension in patients, which often occurs in patients with renal failure. When diabetic patients find that their blood pressure rises, they should not use antihypertensive drugs first, but look for the reasons for the increase. Fourth, in the early stage of renal failure, in order to meet the needs of glucose excretion, glomerular filtration rate increased, and blood urea nitrogen and creatinine levels were normal. After persistent proteinuria, the concentrations of blood urea nitrogen and creatinine increase, resulting in renal insufficiency, which can develop into end-stage renal failure within several years. In addition, diabetic nephropathy is often accompanied by various complications, such as heart failure and cystitis, which often affect renal function. Acute renal failure can also occur when ketoacidosis and hyperosmolar coma are accompanied by circulatory failure. Five, leg cramps The kidney secretes a hormone that regulates calcium and phosphorus metabolism. When the renal function declines, the decrease of this hormone will hinder the reabsorption of calcium, leading to the decrease of blood calcium and bone mass, which is prone to osteoporosis and fracture. Calcium deficiency caused by this kind of kidney disease is generally ineffective in supplementing calcium. When the early symptoms of diabetic nephropathy in middle-aged and elderly people are calcium deficiency symptoms such as leg cramps, don't forget to check the renal function. These are the early symptoms of diabetic nephropathy. If there is a problem, it is necessary to treat it with medicine and diet in time. Hengji Yuetai Capsule is suitable for diabetic nephropathy. Hengji Yuetai Capsule can promote β cell regeneration, regulate islet secretion function, lower blood sugar steadily and prevent complications.