What does frozen man mean?

Frozen people are caused by a disease. When mentioning frozen people, many people may feel weird. What causes frozen people and what are the symptoms when the disease occurs. Literally speaking, frozen people seem to be refrigerated. In fact, cryosurgery turns into motor neurone disease. Because the patient's motor neurons are damaged, the patient's body, body, and chest and abdominal muscles atrophy or weakness.

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1. Causes of the disease

The causes of amyotrophic lateral sclerosis are still unclear. 20% of cases may be related to genetic inheritance and genetic defects. In addition, some environmental factors, such as excessive heavy metal aluminum poisoning, may cause damage to motor neurons. The current main theories that cause damage to motor neurons are:

1. The accumulation of neurotoxic substances and the deposition of phosphate in the middle of neuron cells will lead to damage to neuron cells in the long run.

2. Oxygen free radicals damage nerve cytoplasm.

3. The lack of nerve cell growth factors prevents neuronal cells from continuing to grow and develop.

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2. Clinical symptoms

Early symptoms are mild and easily confused with other diseases. Patients may only feel some symptoms such as weakness, muscle twitching, and easy fatigue, and gradually progress to general muscle atrophy and difficulty swallowing. Eventually respiratory failure results.

Based on clinical manifestations, it can be roughly divided into two types:

1. Physical onset type

The first symptom is idiopathic atrophy and weakness of the limb muscles, and finally This causes respiratory failure.

2. Medulla bulbar onset type

Difficulty in swallowing and speaking occurs in the early stage, and rapidly progresses to respiratory failure.

3. Treatment

Make a diagnosis as soon as possible, provide neuroprotection and supportive treatment as soon as possible, such as Riruta and other drugs, and maintain regular follow-up.

1. General treatment methods

Supportive therapy: medication and moderate exercise. For example, pay attention to the functions of the respiratory system and digestive system. If there is a lot of saliva, a small amount of antihistamine drugs can be given; if there is a lot of phlegm in the cough, atomization and phlegm-reducing drugs can be given; if the mood is depressed, antidepressant treatment can be given. In addition, you should turn the bed frequently to avoid bedsores. If there is an eating disorder, a nasogastric tube or percutaneous gastrostomy (PEG) is given.

2. Special treatment method

At present, the internationally recognized and the only drug approved by the US Food and Drug Administration (FDA) to treat amyotrophic lateral sclerosis is Liru. Too (Rilutek), and must be applied as soon as possible.

3. Inspiratory treatment

When breathing is not smooth at the beginning, you can use ordinary CO2 or a bipositive pressure ventilator (BiBAP) to assist in inhalation. When further respiratory failure occurs, A tracheotomy is required and an artificial ventilator is used.

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4. Research results

At present, the international community is trying to use neurotrophic factors, antioxidants such as vitamin E, vitamin C and Its creatine, CoQ10, etc. are used in conjunction with Rilutek to prevent amyotrophic lateral sclerosis. However, the treatment described has yet to be confirmed by clinical studies. In addition, experts have also carried out experimental scientific research on gene therapy for this disease.

A frozen person is a person whose muscles all over his body gradually lose strength for no reason, as if they were frozen. . . Finally died of respiratory failure, this is called ALS, not frozen person