Can AIDS be cured?

(1) thomas cech, a recent Nobel Prize winner and a professor at the University of Colorado, said: They are studying how to make anti-HIV drugs into missiles and aim them at the precise target in cells-HIV RNA. Once it hits the target, the antiviral agent will split the RNA in two, making it harmless. They used this targeted ribozyme to complete the experiment of destroying the virus in mice. Soon, they will do human experiments.

(2) American scientists unexpectedly found that neomycin is the most effective antiviral drug in aminoglycosides to block the reproduction of HIV, and its function is the first step to interfere with the sequential activities of virus proliferation, so that the virus collapses and cannot continue to proliferate. However, because neomycin has certain toxic and side effects, it is necessary to develop a preparation with the same antiviral effect and lower toxicity as neomycin.

(3) A British pharmaceutical factory claims that an anti-cancer drug (EFB) they developed can kill human white blood cells infected with HIV in test tubes, but it does not harm normal cells. The potential of this drug to treat AIDS is being tested.

2. Study on drugs to block the combination of virus and human cells;

(1) The virus and cellular immunity research group of Pasteur Institute in France has successfully developed a substance that destroys the molecular recognition function of CD 26 protein, but the "vitality" of this substance needs to be improved. It is reported that this anti-AIDS drug will be put into use in about two years.

(2) After half a year's in vitro experiment, a research team of French National Research Center found that CD4 molecules can block the "entrance" of lymphocytes, thus preventing HIV from invading normal cells, and there is no toxic side effect on cells. In vivo experiments will be done on monkeys soon.

(3) Recently, a multi-headed SPC molecule was discovered in the Biochemistry and protein Engineering Laboratory of the Research Center of the University of Marseille, which can intervene when HIV contacts CD4 receptor to prevent HIV from combining with cells.

(4) Researchers at the University of Texas in the United States used a protein contained in HIV to make drugs, which effectively prevented HIV from invading normal cells outside the human body, but no in vivo tests have been conducted.

3. Preparations for protecting or restoring immune function:

(1) A research team in the United States used human protein therapy containing interleukin 12 to restore the immune system of HIV-infected people to prevent the development of AIDS. Only in vitro experiments were done and human experiments were started.

(2) Biological response immunomodulator: Ecuadorian doctor Edwin Ceballos invented a new anti-AIDS drug BIRM, which is a biological response immunomodulator. The analysis and experiments of many laboratories in the United States prove that it can prevent HIV from destroying the immune system. The Ecuadorian Medical Association approved all the test results. Pharmaceutical factories in Germany and Switzerland have obtained the right to mass production and will soon be put on the market.

(3) Gene therapy: American scientist David Weiner conducted gene therapy experiments with mice, rabbits and monkeys, and the results were good. He implanted HIV gene into lymphohistioma, and then transplanted it into mice through lymphohistioma. After 40 days, antibodies and T lymphocytes appeared in mice, indicating that the immune system had a positive resistance to HIV. The results of rabbit experiments show that the time required to produce immune response is shorter than that of mice. The monkey experiment also achieved good results. Gene therapy based on genetic cells is highly praised by experts and is generally regarded as the "future hope" of AIDS treatment.