How to resolve the contradiction between uncle and mother-in-law in life?

Maybe there is something wrong with her. Let your wife persuade her, for example, analyze your difficulties for her and let her try to understand you.

But it's your mother-in-law. I think you can try to be more considerate and tolerant of her.

Is there anything you can't do well? Like arguing with her.

Just like taking medicine at work for you to buy, I think you can say that you are at work and buy it for her after work. If it's important, take it right away, and you can buy it for her right away. I think we can prioritize things.

She asked her daughter to go home. If it is too frequent, you can talk to your wife.

Some things, such as buying a car, can remain silent. If you don't agree to buy a house, you can keep silent.