What does non-invasive DNA mean by low risk?

Being able to have a healthy baby is the common wish of all pregnant women, and every family is most worried about the health of the fetus during pregnancy. Therefore, pregnancy examination is the most critical. So, what are the pregnancy examination items? What does non-invasive DNA mean by low risk?

What do you mean by low risk of non-invasive DNA? Non-invasive prenatal genetic testing is to collect pregnant women's peripheral blood (5ml), extract free DNA, and obtain the risk of fetal chromosome aneuploidy (2 1- trisomy, also known as Down's syndrome, 18- trisomy and 13- trisomy) by using the new generation high-throughput sequencing technology combined with biological information analysis. The best detection time of this method is the first and second trimester of pregnancy, and it has the characteristics of non-invasive sampling, no risk of abortion, high sensitivity and high accuracy.

The results showed that fetal free DNA could be detected in the peripheral blood of pregnant women from the fourth week of pregnancy. With the increase of gestational age, the content of fetal free DNA also increases. After pregnancy 12 weeks, by extracting free DNA from pregnant women's peripheral blood, we can accurately judge whether the fetus has chromosome diseases by using the new generation of gene sequencing technology combined with bioinformatics analysis methods.

The traditional serological screening method calculates the results according to the age, gestational age, hormone level and weight of pregnant women, which has high false positive rate and great risk of missed detection.

Traditional prenatal diagnosis adopts invasive sampling methods, such as villus sampling, amniocentesis and fetal umbilical vein puncture. Although these operations can diagnose whether there is chromosomal aneuploidy in the fetus, puncturing the wound may lead to risks such as infection and abortion.

One week after pregnancy check-up, I went to a trusted hospital for the first check-up and got the maternal and child health manual. Most expectant mothers check 1 time every 4 weeks, every 2 weeks after 28 weeks, and every week after 36 weeks until delivery.

The items of prenatal examination in early pregnancy are generally gynecological endoscopy, vaginal discharge, cervical curettage, gynecological three-diagnosis examination, ultrasound examination and so on.

Other inspection aspects are selected according to their own conditions. If you have heart, liver, kidney, thyroid and other diseases, you need to consult a doctor to find out whether continuing pregnancy will increase the risk.

Early pregnancy examination is mainly to determine the gestational age and confirm the time of pregnancy. Many women are not allowed to menstruate, and the date of ovulation is not exact. If the gestational age is not determined in time in the early pregnancy, it is difficult to calculate the delivery date in the later period, and it is impossible to monitor whether the fetal growth and development are normal and the placental function.

Early pregnancy examination can check whether it is intrauterine or ectopic pregnancy. Ectopic pregnancy is very dangerous because of its high incidence. If ectopic pregnancy breaks, internal bleeding will cause life crisis.

Prenatal examination in early pregnancy can also preliminarily evaluate the physical condition of pregnant women with basic medical diseases such as hypertension, hyperglycemia and nephritis. If so, it depends on the severity, whether treatment is needed, whether pregnancy can continue, how much harm it will do to pregnant women, and take necessary measures as soon as possible to ensure the safety of expectant mothers during pregnancy.

Because of the abnormal phenomena that are easy to appear in the first trimester: threatened abortion, vaginal bleeding and abdominal pain, these situations may also be ectopic pregnancy, so you should see a doctor in time. If it is threatened abortion of intrauterine pregnancy, it should be handled in time to ensure the normal development of the embryo.

Therefore, I hope that every pregnant mother should take good care of her baby and her body and do regular check-ups in time.

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