How should urticaria be treated in Nanning?

Urticaria, commonly known as "rash", is a common allergic skin disease. Urticaria is mainly characterized by red or reddish wheals of different sizes, with severe itching, which usually subsides within 4 hours, and within 24 hours at the longest, leaving no trace after fading, but it can occur many times a day. Urticaria recurs within less than one week or six weeks, which is called acute urticaria; If the recurrent attack lasts more than 1.5 months (6 weeks), it is chronic urticaria.

Why is urticaria easy to recur?

At present, the research on the pathogenesis of urticaria is mostly autoimmune theory, and the incidence of autoimmune urticaria has been paid more and more attention by clinical urticaria research. There is sufficient evidence that some patients with chronic urticaria have functional anti-IgE receptor antibodies and/or anti-IgE antibodies, which can degranulate skin mast cells or basophils. In acute attack, about 58% patients have autoantibodies of IgE molecules, and 25% patients have anti-IgE antibodies. The increase of IgE antibodies in serum is the main reason for the secretion of inflammatory mediators such as histamine.

What should I do if urticaria recurs? What drugs are currently being treated?

At present, antihistamines are the basic measures to treat urticaria, especially chronic urticaria. The second generation of non-sedative antihistamine H 1 has strong antihistamine and other inflammatory mediators, so it has a good therapeutic effect on various types of urticaria, and has become the first-line treatment drug for acute and chronic urticaria in recent years. When the conventional dose 1-2 weeks can't effectively control the symptoms, considering the difference of treatment response of different individuals or urticaria types, patients can choose to change varieties or increase the dose by 2-4 times with informed consent; Combined with the first generation of antihistamines, it can be taken before going to bed to reduce adverse reactions; The main adverse reactions of antihistamines are sedation and central depression, such as drowsiness, drowsiness, headache, dizziness, excitement and dry mouth.

Dr. Xie Peishan, Director of R&D of Taiwan Research Center and Institute of Food and Applied Biotechnology of Taiwan Province Provincial University, found that [Xin Min Kang Allergic Probiotics] can participate in IgE-mediated immune allergic reaction. By measuring the influence of human dendritic cells co-cultured with anti-allergic probiotics * * on IL- 12-regulated Th 1 immunity, an anti-allergic probiotic strain with anti-allergic ability was screened out. [Xinmin Kang Allergic Probiotics] By using active and non-pathogenic microorganisms, the ecological balance of intestinal microorganisms, the largest immune organ of human body, is improved, thus promoting the immune tolerance function. Lactobacillus salivarius has the international patent certification for reducing serum IgE allergic antibody. After continuous supplementation for more than three months, the IgE concentration in the body is reduced, so that allergens cannot bind with IgE antibodies in the body, and a series of allergic biochemical reactions no longer occur. Therefore, it can resist IgE antibody and regulate allergic constitution, while drugs can only relieve symptoms and cannot regulate allergic constitution.

Daily nursing care of urticaria

1. Avoid eating foods with high protein content such as shrimp, crab and fish, so as not to aggravate the illness;

2. Pay attention to environmental hygiene in life and don't keep pets;

3, usually pay attention to exercise, live a regular life, keep a good mood and get enough sleep.