When is it most appropriate to take antihypertensive drugs when suffering from hypertension?

These are two questions. 1. When did you start taking antihypertensive drugs for hypertension? The second question is, if you take antihypertensive drugs for a long time, when is the most appropriate time to take antihypertensive drugs every day?

First, when should I start taking antihypertensive drugs when I have high blood pressure?

First of all, I tell you that if you have high blood pressure, you don't have to take antihypertensive drugs. For newly discovered hypertension, and the blood pressure is not higher than 160/ 100, there are no complications of diabetes or hypertension, such as heart failure, angina pectoris, myocardial infarction and renal failure. At this time, you can temporarily stop taking antihypertensive drugs, and first control your blood pressure through a healthy lifestyle, that is, low-salt diet, quitting smoking and drinking, persisting in exercise, controlling your weight, and avoiding staying up late. If your blood pressure can be reduced to 130/80 within three months, you can continue to live a healthy life to control your blood pressure without taking antihypertensive drugs.

If the blood pressure is still higher than 140/90 after 3 months, consider taking antihypertensive drugs, which is the first case of taking antihypertensive drugs.

Secondly, if hypertension is found to be higher than 160/ 100, or complicated with diabetes, heart failure, myocardial infarction, renal failure, cerebrovascular disease, etc., then antihypertensive drugs must be taken immediately to control blood pressure.

This is when you get high blood pressure and start taking antihypertensive drugs.

2. When is the best time to take antihypertensive drugs every day?

1, I suggest you take long-acting antihypertensive drugs.

Long-acting antihypertensive drugs, once a day, are convenient to take and relatively stable in blood pressure; Short-acting antihypertensive drugs not only need to be taken 2-4 times a day, but also have unstable blood pressure.

Most people take antihypertensive drugs in the morning.

Long-acting antihypertensive drugs are theoretically long-acting sustained-release drugs, so they can be taken at any time, but real cases tell us that most people take antihypertensive drugs in the morning, and the effect is better.

Our 24-hour blood pressure rhythm has two peaks and two valleys, that is, it rises at 6~ 10 in the morning, drops at 2~3 in the afternoon, rises again at 4~6, and then slowly drops to the lowest point at 2~3 in the morning.

Most people have high blood pressure in the morning, which is called morning peak blood pressure. The phenomenon of early peak significantly increases the risk of cardiovascular and cerebrovascular events in the morning in patients with hypertension. In other words, the risk of angina pectoris, even myocardial infarction, stroke and other malignant events is greatly increased in patients with poor blood pressure control in the morning.

Therefore, it is generally recommended that hypertensive patients take antihypertensive drugs in the morning, so that their blood pressure can be basically controlled satisfactorily and various cardiovascular and cerebrovascular emergencies can be prevented in the morning.

3. The latest research has a new formulation

A randomized controlled study in European Heart Journal selected 20,000 people for more than 6 years of follow-up. The study said that antihypertensive drugs were best taken before going to bed. The study found that taking medicine before bed can reduce cardiovascular events by 45% compared with people who take medicine in the morning.

Of course, this is just a study, and there is no conclusion at present. Whether it is necessary to take it before going to bed needs more evidence.

4. What should I do?

1) If you are taking antihypertensive drugs now and your blood pressure is stable, don't change them, just take them according to the time when you are taking antihypertensive drugs.

2) If your blood pressure is unstable after taking antihypertensive drugs, you can find a professional doctor to analyze the reasons. If it is caused by improper medication time, it needs to be adjusted.

The ideal medication time should be individualized, and it is best to decide the medication time according to the 24-hour blood pressure curve. Especially for patients with unsatisfactory blood pressure control, 24-hour ambulatory blood pressure monitoring should be carried out, and doctors should adjust the medication time accordingly.

3) For blood pressure that is difficult to adjust, it is best to bring a ambulatory blood pressure monitor to observe the fluctuation of blood pressure, and then adjust the medication plan and time.

Because everyone's specific situation is different, there is no uniform standard for the time to take antihypertensive drugs. The principle is that after we take antihypertensive drugs, our blood pressure will be more stable, so we should take them at this time.

For most people, first take long-acting antihypertensive drugs in the morning, and then make further adjustments if the effect is not good.

But more importantly, you should monitor your blood pressure. Otherwise, how do you know if your blood pressure is stable?