How to treat Parkinson's disease

Parkinson's disease is a neurodegenerative disease in middle-aged and elderly people, which can have motor symptoms and non-motor symptoms. Parkinson's disease is more common after the age of 60, with slightly more males than females. Motor symptoms often start from one upper limb, gradually affect the same lower limb, and then affect the opposite upper limb and lower limb. Motor symptoms include static tremor, myotonia, bradykinesia and postural balance disorder. Non-motor symptoms are also common and important clinical signs, which can occur years before or even after motor symptoms, including sleep disorders and autonomic nervous dysfunction. It is suggested that patients can supplement endogenous dopamine by improving dopamine status, for example, drugs such as dopamine receptor agonists can be used for treatment. In addition, surgery can also be performed, which can be used as a supplementary treatment for drug treatment. Parkinson's disease (PD) is a common neurodegenerative disease in middle-aged and elderly people, which is characterized by the loss of dopaminergic neurons in substantia nigra striatum and Lewy bodies. It is common in people over 60, but it occasionally appears in young people in their twenties. The main clinical symptoms are tremor, myotonia, bradykinesia, loss of posture reflex and abnormal balance. , the specific performance is the following symptoms:

1. Tremor: Typical patients show static tremor, mostly originating from the distal end of one upper limb. It is characterized by slow, moderate or thick tremor, which is aggravated when patients are nervous, excited, tired and anxious, and disappears after falling asleep;

2, myotonia: can appear in the early stage of the disease, mainly affecting the muscles of the trunk and proximal limbs. When the patient moves passively, the joint resistance increases and the limb can appear gear-like rigidity;

3, slow movement: spontaneous movement is reduced, the movement is slow and clumsy, such as lack of facial expression and blinking movement, similar to mask face. When walking, the upper limb swing decreases or disappears, writing becomes smaller and smaller, gait is flustered, speech is too slow, and swallowing is difficult;

4, posture reflex loss and abnormal balance: easy to fall, or even stand independently. When I changed from standing position to sitting position, my whole body fell into the chair. When the patient is in an unstable posture with the head forward and the trunk forward or backward, it is difficult to keep upright and easy to fall;

5. Other symptoms: depression, anxiety, depression, dementia, pain, hypoesthesia, sleep disorder, cognitive disorder, constipation, slow urination, postural hypotension, blepharospasm, etc. Patients with advanced stage may even have hallucinations.