Can postoperative analgesics produce dependence? How to relieve pain is the best?

1. Will postoperative analgesics produce dependence? How to relieve pain is the best? Dependence will happen, depending on the individual's physical condition. Postoperative analgesia has side effects, which are related to analgesic drugs and methods. Non-steroidal anti-inflammatory drugs and opioid analgesics are commonly used for postoperative analgesia, which have antipyretic, analgesic, anti-inflammatory and anti-rheumatic effects. The main mechanism of analgesia is to inhibit the synthesis of cyclooxygenase and prostaglandin, and its side effects include coagulation dysfunction, renal dysfunction, gastrointestinal bleeding, bronchospasm and so on. Opioid analgesics, also known as narcotic analgesics, are the most commonly used drugs to treat moderate and severe acute and chronic pain. There are two main types of painkillers. The painkillers that most people will buy have some dependence, but it depends on the degree, usually the body, not what people call addiction. So there is really no pain.

Due to the lack of professional medical knowledge, people mistakenly think that human dependence on painkillers is addiction. Many people are frightened by the tears and snot of drug addicts and mistakenly think that this is "addiction", but the symptom of this painkiller is called "withdrawal" and it is a kind of "dependence". Central analgesic: Tramadol is a central analgesic. The analgesic effect of tramadol is better than that of ordinary antipyretic analgesics, but compared with narcotic analgesics, its analgesic effect is only one tenth of that of morphine, and it is mainly used for mild acute pain and postoperative pain. Narcotic analgesics: narcotic drugs are the main drugs, which have good analgesic effect, but they will be dependent on long-term use. This drug is used under a strict system and should not be used at will. It is mainly used for patients with severe postoperative pain and patients with advanced cancer.

3. It is mostly used for postoperative analgesia and can be administered by intravenous, epidural, subcutaneous and peripheral nerve block. The common side effects are mainly related to the drugs used and the analgesic methods. The side effects related to epidural analgesia and opioids also include itching, sedation, dizziness and urinary retention; Hypotension, sensory changes and urinary retention are related to local anesthetics. Unilateral leg numbness and motor block are the side effects of local anesthetics, which are usually related to the displacement of epidural catheter tip to nerve root, which may slow down the speed of catheter withdrawal or infusion.