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Can hepatitis B carriers give birth to healthy babies?
First of all, for female hepatitis B virus carriers, as long as their liver function is normal, they can consider getting pregnant and having children.
How to detect liver function during pregnancy?
Note: During pregnancy, besides having a good rest and regular physical examination, you must also have a liver function examination every one to two months. If you find abnormal liver function, you should go to the liver disease specialist for consultation and treatment in time. In addition, quantitative examination of HBV DNA should be carried out.
Three main ways of mother-to-child transmission of hepatitis B virus
Whether the child is in danger and healthy can be analyzed from three main ways of mother-to-child transmission of hepatitis B virus:
1. intrauterine infection, that is, fetal infection in the mother.
2. Intrapartum infection, that is, during childbirth, the fetus comes into contact with maternal blood, amniotic fluid and secretions containing hepatitis B virus when passing through the birth canal; Or because of uterine contraction, placental villous blood vessels rupture, resulting in a small amount of maternal blood infiltrating into fetal blood circulation and causing infection.
3. Postpartum infection refers to the spread through breastfeeding and close contact in life.
Generally speaking, the probability of the first infection is very small, and the other two cases can be effectively blocked by medical means, that is, the newborn is injected with hepatitis B immunoglobulin (HBIG) within 24 hours after birth (preferably within/0/2 hours after birth), and the dose should be greater than or equal to 100 international unit, and at the same time, the recombinant yeast hepatitis B vaccine is inoculated in different parts.
For male HBV carriers, the most effective method is pre-pregnancy intervention.
I hope the answer will help you. 2 1
Hello! That's a good question!
Once the baby is born, pregnant mothers with hepatitis B virus need to inject hepatitis B immunoglobulin immediately, then inject a second dose of hepatitis B vaccine, and then inject the second and third doses of hepatitis B vaccine at intervals of 1 month and 6 months respectively, which can play an active and passive role in preventing hepatitis B virus and basically completely block it. So the baby of hepatitis B virus carrier is healthy, don't worry!
In addition, I would also like to remind pregnant mothers that if you don't have hepatitis B, but your husband or in-laws have hepatitis B, because they are in close contact with the baby, it is recommended that the baby be immunized actively and passively after birth, that is, injected with hepatitis B immunoglobulin and hepatitis B vaccine after birth!
Hepatitis B is a chronic disease with great harm. China is a big country with hepatitis B, and one in every ten people is a carrier of hepatitis B virus. Some people with hepatitis B virus carriers may never get sick, and some people develop into small three-yang, big three-yang, liver cirrhosis, liver ascites and liver cancer. There is no cure for liver disease in the world now, and it can only be effectively controlled. Getting hepatitis B is equivalent to a suspended death sentence, which greatly reduces people's quality of life. There are several ways of transmission of hepatitis B, including sexual transmission, blood transmission and mother-to-child transmission.
One of the transmission routes of hepatitis B virus is mother-to-child transmission, so a comprehensive physical examination must be carried out before conception. If the man carries hepatitis B virus, his liver function is normal, the woman is not a virus carrier, and other indicators are normal, he can give birth to a healthy baby. If the man is healthy and the woman carries hepatitis B virus, the liver function is normal, the virus content is low and it is not contagious. The baby born at this time is very likely to be healthy. If the woman's virus content is high, she should be treated with antiviral therapy under the guidance of a doctor, and then get pregnant after controlling her condition.
At present, there are three main modes of HBV transmission: blood transmission, mother-to-child transmission and sexual contact transmission. Among them, vertical transmission from mother to child plays an important role in infants infected with HBV. Since 1992, China has begun to implement passive-active immunization to block vertical transmission from mother to child, and the success rate has reached 80% ~ 95%, but there are still 5% ~ 10% of infants who have not been blocked. According to WHO, the failure rate of immunotherapy is 8% ~ 32% at present, and the risk is higher if the mother's HBV DNA is ≥10.7iu/ml or higher. The reason of HBV blocking failure is that hepatitis B E antigen (HBeAg) is positive and HBV DNA level is ≥ 6 ~ ≥6~7log 10 IU/ml.
China's 20 15 edition of "Guidelines for the Prevention and Treatment of Chronic Hepatitis B" points out that tenofovir disoproxil fumarate and Teflon can be taken in the 24th to 28th week of pregnancy if the HBV DNA level is more than 2.0×106 iu/ml (/kloc-0 /×107 copies/ml). But I still need to see a doctor.
In short, hepatitis B carriers can give birth to healthy babies, but it is useless to play immunoglobulin during pregnancy!
If it's a woman
1 Go to the hospital for physical examination, liver function test, etc. , mainly listen to the doctor's advice.
Pregnancy preparation is more careful than the average woman.
Listen to the doctor's advice after pregnancy and have a mother-to-child blocking needle.
After the child is born, get hepatitis B vaccine and anti-hepatitis B immunoglobulin, and listen to the doctor to see if you can breastfeed.
In this way, the probability of mother-to-child transmission will drop a lot, but everything is not absolute.
If it is a male, it will generally not be passed on to the child, and normal pregnancy will do. Spouses must check five items of hepatitis B, get hepatitis B vaccine, and strengthen the injection regularly after having antibodies. Take hepatitis B vaccine after the child is born, and be careful not to spread blood.
Most importantly, follow the advice of professional doctors.
Can couples with hepatitis B virus give birth to healthy babies? The answer is yes! First of all, let's take a look at the two halves of hepatitis B. The two halves of hepatitis B are: 1: hepatitis B surface antigen, 2: surface antibody, 3:e antigen, 4:e antibody and 5: core antibody. Clinically, it is usually said that Big Sanyang 1, 3,5 are positive, and Small Sanyang 1, 4,5 are positive. Positive surface antigen is hepatitis B carrier, and what we call hepatitis B vaccine is: hepatitis B surface antibody.
People with antibodies are generally not infected when they come into contact with hepatitis B patients.
Second, talk about the route of transmission of hepatitis B: Pregnant women with hepatitis B are injected with hepatitis B immunoglobulin in the third trimester according to the textbook before version 20 17. Intramuscular injection of hepatitis B immunoglobulin within 24 hours after delivery, once at full moon and once every six months, the blocking rate can reach 99%. Later, after 20 17, the textbook said that there is no need to inject immunoglobulin during pregnancy, as long as the baby is injected once every 24 hours after birth. So now we all inject once every 24 hours after the baby is born.
Third: hepatitis B carriers and couples are not contagious. The most contagious is hepatitis B big three-yang, followed by hepatitis B small three-yang. I have a relative who is hereditary big three-yang. At that time, people may be too ignorant, and ignorant people have nothing to hide! Both her mother and her brother have big three-yang, so pregnant women with hepatitis B who are not blocked will pass 100% to the fetus. Later, when she was 24 when she was pregnant with her first child, she had a detailed prenatal examination. She is Xiao Sanyang, who was injected with immunoglobulin in the third trimester. Infants are injected with immunoglobulin 24 hours after birth, once at the full moon and once every six months. Now the child is six years old, and there are hepatitis B antibodies in both halves of the physical examination every year, which shows that this baby is a healthy baby!
Therefore, pregnant women must pay attention to prenatal examination during pregnancy, not blindly. However, after delivery, in order to prevent the nipple from being sucked by the newborn and infecting the baby, the general hepatitis B mother should not breastfeed. If you insist on breastfeeding, you need to test the DNA of HBV. If it is positive, don't insist on breastfeeding!
Hello, I'm Man Huajun, and I'm glad to answer your questions! First of all, let's briefly introduce hepatitis B!
The discovery of hepatitis B pathogen is a milestone in the history of science. 1965, Bloomberg and his colleagues found a precipitate in the serum of Australian aborigines and named it Australian antigen. Subsequent studies confirmed that Australian antigens were directly related to hepatitis B virus (HBV) infection. In 1970s and 1980s, a large number of epidemiological studies showed that chronic HBV infection was closely related to the occurrence of chronic liver disease, liver cirrhosis and liver cancer.
Hepatitis B is not a genetic disease, but a DNA virus, which mainly attacks healthy liver cells. Its main transmission routes include vertical transmission from mother to child, sexual contact transmission and blood transmission. Mother-to-child transmission mainly occurs in the perinatal period, and most of them are exposed to the blood and body fluids of HBV-positive mothers during childbirth.
Hepatitis B is not caused by genetic mutation, so it will not be passed on to children. At the same time, IVF is fertilized in vitro and then put back into the uterus for development; So, it's not genetic. But if the mother is infected with hepatitis B or a patient, we should pay attention to the vertical transmission from mother to child.
So what should we do about vertical mother-to-child transmission? First of all, before doing IVF, it is necessary to have a physical examination for hepatitis B patients, usually during pregnancy. It is necessary not only to look at the pregnant fetus, but also to check the liver function. Especially for hepatitis B patients, antiviral treatment is needed to effectively inhibit the replication of hepatitis B virus in the body. Suppress the virus at a low level; Secondly, for pregnancy and childbirth, we must do a good job of mother-to-child blocking, and now the technology of mother-to-child blocking is very developed; Generally divided into three stages: before production, during production and after production:
In this way, it is effective to successfully block the mother-to-child transmission of hepatitis B.
Hepatitis B Vaccine The development and use of hepatitis B vaccine in China has also gone through two stages: blood-borne hepatitis B vaccine and recombinant hepatitis B vaccine. China's blood-borne hepatitis B vaccine was successfully developed in 1985, and was approved for marketing in 1986. Because of the potential danger of this vaccine, the Ministry of Health stipulated that the production of blood-borne hepatitis B vaccine should be stopped from 1998 to June 30, 2000. Domestic CHO vaccine for hepatitis B was approved for trial production in 1992 and officially produced in 1996. 1997 domestic recombinant yeast hepatitis b vaccine was officially produced. At present, all vaccines used in China are genetically engineered vaccines.
In short, with such advanced technology, hepatitis B patients want a healthy baby, and mother-to-child blocking, hepatitis B vaccine and immunoglobulin can greatly reduce the occurrence of mother-to-child transmission. Therefore, hepatitis B patients and virus carriers must actively treat, develop good living habits, and cooperate with the current mother-to-child blocking technology to have a healthy baby!
Hepatitis B virus carriers can get pregnant completely, so don't worry about it. Generally, when pregnant for 7, 8 and 9 months, it can be blocked by injecting hepatitis B immunoglobulin. Normal and correct use of hepatitis B immunoglobulin can prevent fetal inheritance, and there is no need to worry at all, and the fetus needs to be injected with hepatitis B immunoglobulin and hepatitis B vaccine in time after delivery.
Many women with hepatitis B virus carriers are afraid to get pregnant because they are worried that their hepatitis B virus will be transmitted to the next generation.
If the patient is only positive for hepatitis B surface antigen, or a little positive, and the DNA of hepatitis B virus is negative, he can get pregnant, so the hepatitis B virus in the patient is in a stable state at this time. After pregnancy and delivery, newborn babies can be vaccinated with hepatitis B vaccine within 24 hours after birth to avoid being infected with hepatitis B virus.
If the patient is diagnosed as a big three-yang disease and HBV DNA is positive, the doctor suggests that such patients should be treated first, and then get pregnant after HBV DNA is negative. This practice is not only for the baby's health, but also for the patient's own life safety. A large number of clinical cases show that there are many cases of hepatitis B virus carriers turning into liver cancer, so patients with hepatitis B must pay attention to their own situation.
Hepatitis B virus carriers can get pregnant completely, so don't worry. In general, when they are 789 months pregnant, they can be blocked by injecting hepatitis B immunoglobulin. Normal and correct use of hepatitis B immunoglobulin can prevent fetal inheritance, and there is no need to worry at all, and the fetus needs to be injected with hepatitis B immunoglobulin and hepatitis B vaccine in time after delivery.
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