Breast cancer immunohistochemistry results, please help explain

The following text is just typed by hand, no copying is required. The current stage is T2N0M0. Although it is not very early stage, it can still be regarded as early to mid-stage. If you persist in treatment, the effect will be good.

I will send you a picture, which is the survival analysis of the patient. It can be seen that the 5-year survival rate of such patients is 94%, the 10-year survival rate is 87%, and the 15-year survival rate is . 81%. The above is the patient’s prognosis, to give you reassurance first. Among cancers, the treatment effect is almost the best. Let’s talk about treatment:

1. Chemotherapy. Stage IIA invasive ductal carcinoma requires chemotherapy. Your doctor has chosen a relatively mild and effective plan that is suitable for you, which should be TC4 times. This side effect is minor. A white blood cell count of 1.3 indicates severe bone marrow suppression and requires white blood injections. There are domestic and imported drugs. The imported drugs are more expensive and more effective. Some people will have severe bone pain when they get this injection. I suggest you buy some painkillers from a large drugstore for your mother. Take the painkillers to relieve the pain for a day or two and then it will pass. White blood cells are very low! ! Very! ! Dangerous? It is easy to get infected. Do not go to crowded places. It is recommended to wear a mask. If someone in the family has a cold, do not stay in contact with them for too long. It is recommended to review the blood routine every 3-4 days after the next chemotherapy, and change it to 4-5 days until 14 days after chemotherapy.

2: Radiotherapy, breast-conserving surgery must undergo radiotherapy, otherwise the local recurrence rate will be as high as 50% within 2 years. There are many methods of radiotherapy, and the choice is based on the family's financial situation. No matter which one you choose, be sure to do it. Only breast-conserving + radiotherapy can achieve the same therapeutic effect as modified radical mastectomy.

3: Endocrine therapy: Both ER and PR are strongly positive, and the effectiveness of endocrine therapy is 60-70%. You are not a professional and do not understand the meaning. The effectiveness of 60-70% means that even if About 70% of patients do not undergo chemotherapy but only use endocrine therapy. This shows how effective endocrine therapy is. Even now when we go to meetings, many experts mention that the current treatment of breast cancer is not traditional. Comprehensive treatment centered on surgery, but comprehensive treatment based on endocrine therapy. Plan: If the patient is not menopausal, use tamoxifen or raloxifene for 5 years. If the patient is menopausal, use the following plan

1) Tamoxifen or raloxifene for 5 years? Or

1) Tamoxifen for 2-3 years + aromatase inhibitor (letrozole, anastrozole or exemestane) for 3-2 years, total ***5 years

2) Instead of tamoxifen, use aromatase inhibitors (letrozole, anastrozole or exemestane) for 5 years

4. Molecular targeted therapy, patient Her2++, clinical It is still uncertain whether the gene is amplified, and FISH needs to be done to confirm. This test costs 2,000 yuan in Guangzhou. But overall, only about 10% of patients with two plus signs of Her2 are true positive. If they are positive and have good family conditions, they can receive Herceptin treatment, which costs only 300,000 yuan a year. Fortunately, there are free drugs in Guangzhou According to the plan, 150,000 is about the same.

One final point: You must encourage the patient. Your strong support is the greatest help to her.