What are the phenomena of pesticide poisoning?

The phenomenon of pesticide poisoning is not particularly rare around us. The occurrence of pesticide poisoning has seriously endangered the health and life safety of patients and friends. Therefore, we must attach great importance to the occurrence of this disease. What are the specific symptoms of pesticide poisoning?

Pesticide poisoning is one of the main causes of poisoning and accidental death, most of which are acute life poisoning, mainly caused by accidental ingestion or suicide and pesticide abuse. Pesticide poisoning caused by environmental pollution in production mainly occurs in packers produced in pesticide plant and pesticide users in rural areas. When spraying pesticides or dispensing drugs in the field, and overhauling the application tools, the skin is easily polluted by pesticides, and it is easy to cause acute poisoning through absorption through the skin and respiratory tract.

What are the specific symptoms of pesticide poisoning?

1. Skin and mucous membrane irritation symptoms After oral intake, the oral mucosa and throat are stimulated, causing pain, mild burns and ulceration, forming oral ulcers; The root of the eye is polluted and there are signs of conjunctivitis; Undiluted preparations pollute the skin, causing itching and erythema when stimulated locally, and a few patients have skin allergies.

2. Digestive tract reaction is often the main symptom of acute oral poisoning. In addition to swelling and swelling of oral mucosa, nausea, vomiting and epigastric pain often occur, and in severe cases, gastrointestinal bleeding and diarrhea occur.

3. Respiratory system injury can cause cough and asthma, and it is difficult to clear the mirror of the lungs. (5) Pulmonary edema, cough, chest tightness, dyspnea, and severe cases may die of respiratory failure.

4. In addition to tachycardia or bradycardia, cardiovascular injury often leads to a drop in blood pressure. In the early stage, the decrease of blood pressure may be the influence of the decrease of blood volume, but in the later stage, it is the effect of the poison itself. Dogs were injected with pure glyphosate and surfactant respectively, and it was found that the blood pressure of those injected with surfactant decreased. Creatine kinase (CK) increased in some cases.

5. Nervous system symptoms are generally not seriously damaged except dizziness, fatigue and sweating; However, when high-dose oral poisoning is serious, abnormal consciousness, convulsion and coma may also occur.

6. Liver and kidney damage is generally mild, which can often be recovered automatically, but individual patients may cause serious kidney damage or even acute renal failure due to hemolysis.

Clinical manifestations:

1, clinical manifestations of acute poisoning can be divided into three categories:

(1) Muscarinic symptoms: It can appear in the early stage, mainly manifested as loss of appetite, nausea, vomiting, abdominal pain, diarrhea, salivation, sweating, blurred vision, miosis, increased respiratory secretions, and pulmonary edema in severe cases.

(2) Nicotine-like symptoms: when the illness gets worse, the whole body feels tense, the speech is unclear, the muscles in the chest, upper limbs, face and neck and even the whole body tremble, the chest feels oppressive, the heart rate is accelerated, the blood pressure is increased, and in severe cases, respiratory paralysis occurs.

(3) Central nervous system symptoms: dizziness, headache, fatigue, restlessness, ataxia, coma and convulsion in severe cases, which are often life-threatening due to respiratory center or respiratory muscle paralysis.

(4) Delayed neuropathy: Generally, from the 8th day to14th day after the symptoms of acute poisoning are relieved, sensory disturbance occurs, followed by weakness of lower limbs until flaccid paralysis of the distal lower limbs, and in severe cases, upper limbs may be involved, mostly bilaterally.

2. Chronic poisoning is very common among workers in pesticide plant.

The prominent manifestations are neurasthenia syndrome and decreased cholinesterase activity. Some organophosphorus pesticides can cause bronchial asthma, allergic dermatitis and contact dermatitis.