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Is amoxicillin an antibiotic?
Amoxicillin belongs to penicillin antibiotics, and its mechanism of action is that it binds to pbps on bacterial cell membrane, blocking the synthesis of mucin, damaging cell wall, causing cell rupture and death, and has no effect on the synthesized cell wall, so it is a bactericide in breeding period, with strong activity and low toxicity. The following pharmacists in Yixian introduce the antibacterial spectrum, clinical application, adverse reactions and precautions of amoxicillin:
Antibacterial spectrum:
Amoxicillin belongs to broad-spectrum penicillin, which is acid-resistant and can be taken orally. It has a broad antibacterial spectrum and has strong antibacterial and bactericidal effects on most pathogenic G+ bacteria and G- bacteria (including cocci and bacilli). Among them, Streptococcus pneumoniae, Streptococcus hemolyticus and other streptococcus genera; Aerobic gram-positive cocci such as Staphylococcus and Enterococcus faecalis do not produce penicillinase; Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae and other aerobic gram-negative bacteria and Helicobacter pylori that do not produce β -lactamase have good antibacterial activity.
Some gram-negative bacteria such as Klebsiella pneumoniae, Acinetobacter, Proteus vulgaris and Legionella are resistant to amoxicillin, but amoxicillin is ineffective against mycoplasma and chlamydia without cell walls. When amoxicillin is often combined with β -lactamase inhibitors such as clavulanic acid, the antibacterial effect is obviously enhanced, and clavulanic acid can protect amoxicillin from being hydrolyzed by β -lactamase Amoxicillin and potassium clavulanate have good antibacterial activities against enzyme-producing Staphylococcus and Enterococcus. But it is resistant to methicillin-resistant Staphylococcus (MASA).
Clinical application:
Amoxicillin is suitable for infections caused by the following sensitive bacteria (strains that do not produce β -lactamase):
1, upper respiratory tract infections such as otitis media, sinusitis, pharyngitis and tonsillitis caused by hemolytic streptococcus, streptococcus pneumoniae, staphylococcus or Haemophilus influenzae;
2. Urogenital tract infection caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis;
3. Skin and soft tissue infections caused by hemolytic streptococcus, staphylococcus or Escherichia coli;
4. Lower respiratory tract infections, such as acute bronchitis and pneumonia caused by hemolytic streptococcus, streptococcus pneumoniae, staphylococcus or Haemophilus influenzae;
5. Acute simple gonorrhea;
6. It can be used to treat typhoid fever, other salmonella infections, typhoid fever carriers and leptospirosis; Amoxicillin can also be used in combination with clarithromycin and lansoprazole to eradicate Helicobacter pylori in stomach and duodenum and reduce the recurrence rate of digestive tract ulcer.
According to the Guiding Principles for Clinical Application of Antibacterials, amoxicillin can be used for the following infectious diseases:
1. Acute bacterial pharyngitis and tonsillitis: The main pathogen of infection is group A hemolytic streptococcus, and amoxicillin/kloc-0 can be taken orally for 0/0 day.
2, acute bacterial otitis media, sinusitis: initial treatment can be oral amoxicillin. For example, local Haemophilus influenzae and Moraxella catarrhalis producing β -lactamases can take amoxicillin/clavulanic acid orally.
3. Mild chronic obstructive pulmonary disease: empirical medication can choose amoxicillin or amoxicillin/clavulanic acid.
4. Bronchiectasis complicated with infection: Amoxicillin/clavulanic acid can be selected, and there is no risk of Pseudomonas aeruginosa infection.
5. Community-acquired pneumonia: The initial treatment can be amoxicillin or amoxicillin/clavulanic acid.
6, urinary tract infection: optional amoxicillin or amoxicillin/clavulanic acid.
7. Bone and joint infection: amoxicillin or amoxicillin/clavulanic acid can be selected.
8. Oral and maxillofacial infection: amoxicillin or amoxicillin/clavulanic acid should be selected.
9. Eradication of Helicobacter pylori: Triple therapy with proton pump inhibitor (such as omeprazole) and another antibacterial drug (such as clarithromycin or metronidazole) is used to eradicate Helicobacter pylori.
Main adverse reactions:
1, allergic reaction symptoms: drug fever, urticaria, rash and asthma may occur, and anaphylactic shock is rare.
2. Symptoms of digestive system: common symptoms such as diarrhea, nausea and vomiting, and occasional gastrointestinal reactions such as pseudomembranous colitis.
3, blood system symptoms: occasionally eosinophilia, leukopenia, thrombocytopenia, anemia and so on.
4, occasionally appear excitement, anxiety, insomnia, dizziness and abnormal behavior and other central nervous system symptoms.
5. Long-term use of this drug may lead to double infection of candida or drug-resistant bacteria.
Precautions for medication:
1, penicillin skin test must be carried out before using amoxicillin, and those who are positive are prohibited.
2. Amoxicillin is a prescription drug. Patients should not take it by themselves, let alone take it for a long time.
3. Use with caution those with allergic history such as asthma and hay fever.
4, such as anaphylactic shock, should be on-site rescue, keep the respiratory tract open, oxygen inhalation and application of adrenaline, glucocorticoid and other treatment measures.
5. Amoxicillin requires high storage environment, and should be stored in a cool, dark and dry place in a dark and sealed way.
6. Severe digestive system adverse reactions, such as diarrhea and vomiting. , must stop immediately.
7. When amoxicillin is combined with contraceptives, it will interfere with the intestinal and liver circulation of contraceptives, thus reducing its curative effect.
8. Allopurine uric acid synthesis inhibitors (such as allopurinol) can increase the risk of skin adverse reactions caused by amoxicillin.
Q: Is amoxicillin an antibiotic?
First of all, let's understand what "antibiotics" are. Antibiotics are substances produced by microorganisms that can inhibit or kill other microorganisms. Antibiotics and synthetic antibacterial drugs are collectively called antibacterial drugs because they can inhibit or kill bacteria.
By inhibiting the synthesis of bacterial cell wall, amoxicillin can make bacteria quickly become spheroids, dissolve and rupture, thus playing a role in sterilization. Therefore, amoxicillin is an artificial semi-synthetic antibiotic in antibacterial drugs and belongs to broad-spectrum penicillins. It has bactericidal effect on both gram-negative bacteria and gram-positive bacteria. Can be used for treating sinusitis, otitis media and lower respiratory tract infection caused by Haemophilus influenzae and Moraxella catarrhalis infection; Urinary tract and reproductive system infections caused by Escherichia coli, Klebsiella and Enterobacter; And skin and soft tissue infections caused by methicillin-sensitive Staphylococcus aureus, Escherichia coli and Klebsiella.
Q: Under what circumstances can children take amoxicillin when they have a cold?
What we commonly call "cold" is called acute upper respiratory infection in medicine, which is referred to as upper respiratory inflammation caused by various reasons and is the most common disease in children. It often happens when the seasons change and the temperature changes greatly, especially in winter and spring. Generally, the onset is more urgent, which can be manifested as sneezing, stuffy nose, runny nose and throat discomfort. Some children may also have hearing loss due to eustachian tube obstruction, and may also have symptoms such as tears, dull taste, poor breathing, cough and a small amount of expectoration. Usually, the symptoms are mild, the fever is not obvious or only low fever, except for infants and young children.
Because the immune function of infants and young children is not yet fully mature, infants and young children often have mild catarrh symptoms in the nasopharynx, and the systemic symptoms are serious, which can cause sudden onset, high fever, cough, loss of appetite, abdominal pain, vomiting, diarrhea, irritability, and even febrile convulsions.
More than 90% of colds are caused by virus infection, and the course of disease is mostly self-limited. Generally, it is not necessary to use antibacterial drugs, and it can be cured by symptomatic treatment. A small number of children can have primary or secondary bacterial infection on the basis of virus infection, and only use antibacterial drugs when there are symptoms of bacterial infection. If the total number of white blood cells, neutrophils and/or C-reactive protein in children's peripheral blood picture increase, accompanied by runny nose or cough with yellow pus and phlegm, hearing loss, earache, etc. It is believed that there may be bacterial infection and antibacterial drugs need to be given under the guidance of a doctor.
So under what circumstances do you eat amoxicillin?
Because of the anatomical and physiological characteristics of children's respiratory system, bacterial infection is secondary to cold, which often causes otitis media, sinusitis, tonsil pharyngitis, retropharyngeal abscess, cervical lymphadenitis, laryngitis, tracheitis, bronchopneumonia and so on. Among them, bacterial otitis media, sinusitis and tonsillitis are recommended to be given oral amoxicillin for initial treatment, as shown in the following table.
Note: Amoxicillin-clavulanic acid: The ratio of amoxicillin to potassium clavulanate is 7: 1, and clavulanic acid is a β -lactamase inhibitor. The effective combination of the two can effectively enhance its antibacterial activity, which is more effective for drug-resistant bacteria and has better antibacterial effect.
refer to
Expert consensus on standardized diagnosis and treatment of common cold in children in China (20 13)
Diagnosis and treatment of acute tonsillitis in children: guidelines for clinical practice (formulated on 20 16)
Diagnosis and treatment of acute infectious rhinosinusitis in children —— Clinical practice guidelines (20 14)
Guiding Principles for Clinical Application of Antibacterials (Version 20 15)
Author: Wang Jingyu, member of Pharmacy Department and Pharmacy Network of the First People's Hospital of Chenzhou City, Hunan Province.
Authoritative interpretation of pharmaceutical affairs network, unauthorized reprint, plagiarism will be investigated.
Amoxicillin is the most common drug in our life, and it is also the favorite drug used by ordinary people. When we have redness, swelling, pain, sore throat, sometimes stomachache and discomfort, we think we have inflammation and take amoxicillin orally.
We usually describe amoxicillin as an anti-inflammatory drug, but this statement is wrong. In fact, it is an antibiotic, and it is the most commonly used semi-synthetic penicillin broad-spectrum antibiotic. By inhibiting the synthesis of bacterial cell wall, bacteria can quickly become spheroids to dissolve and rupture, which has a strong and rapid killing effect on both gram-negative bacteria and positive bacteria.
Anti-inflammatory drugs are drugs that inhibit the inflammatory process, that is, anti-inflammatory drugs, which can be divided into non-steroidal anti-inflammatory drugs or steroids, also known as hormones. Non-steroidal anti-inflammatory drugs: aspirin, metamizole, acetaminophen, etc.
Answer clearly! Amoxicillin is an antibiotic, so the use of amoxicillin needs to be carried out under the guidance of a doctor and requires a prescription from a doctor. It is best not to use antibiotics indiscriminately, which will cause flora imbalance or drug resistance, and it is not good for the body itself!
Amoxicillin can be said to be the most classic and successful antibiotic, without one. If penicillin is the master who founded β -lactam antibiotics, amoxicillin is definitely a milestone. It is not only the most widely used semi-synthetic penicillin, but also a kind of penicillin drugs with a wider antibacterial spectrum. The first generation of penicillin antibiotics can only target cocci and a few bacilli among a variety of Gram-positive bacteria in a variety of pathogens, while amoxicillin not only has a good effect on cocci, but also has a good antibacterial effect on a variety of bacilli, greatly expanding the antibacterial spectrum of penicillin antibiotics.
Applicable to the following infectious diseases:
(6) It can be used to treat typhoid fever, other salmonella infections, typhoid fever carriers and leptospirosis; Amoxicillin can also be combined with clarithromycin and lansoprazole to eradicate Helicobacter pylori in stomach and duodenum and reduce the recurrence rate of digestive tract ulcer.
It can be seen that the anti-infection scope of amoxicillin includes upper and lower respiratory tract, urinary tract and abdominal organs, and it has a good effect on various cocci and most bacilli.
Amoxicillin not only has a broad antibacterial spectrum and good bactericidal effect, but also can be widely used and administered through various routes. As we all know, the absorption efficiency and degradation of various drugs in gastrointestinal tract are different, and the amount of some drugs absorbed into blood after oral administration is less than 30%, which greatly limits the use of drugs. In this regard, amoxicillin can be said to be far ahead, and the amount absorbed from the gastrointestinal tract is more than 90% of the oral dosage.
Although amoxicillin is a safe and effective drug, it also has many shortcomings, such as side effects and drug resistance, and it cannot be used with many drugs, among which the following points need special attention.
1, penicillin allergy is prohibited.
2. It may cause leukopenia and thrombocytopenia. Use with caution in patients with hematological diseases.
3. Allergic diseases such as asthma, eczema, hay fever and urticaria; Herpes virus infection, especially infectious mononucleosis (which can increase the risk of skin adverse reactions); It should be used with caution
4, pregnant women and lactating women and children under 3 months with caution. After being applied to pregnant women in the third trimester of pregnancy, it can reduce the concentration of bound estrogen in plasma, but has no effect on free estrogen and progesterone. This product can be excreted through breast milk, and the baby can be sensitized by the nursing mother after using this product.
5. When amoxicillin is combined with contraceptives, it will interfere with the intestinal and liver circulation of contraceptives, thus reducing its curative effect.
6. Allopurine uric acid synthesis inhibitors can increase the risk of skin adverse reactions caused by amoxicillin.
7. Even if the penicillin skin test is negative, the allergic phenomenon cannot be completely avoided.
At present, the drug resistance of amoxicillin is serious. Although it is a penicillin antibiotic with a wide antibacterial spectrum, its antibacterial range is relatively narrow compared with azithromycin and fluoroquinolones. Therefore, if the effect of using this drug is not good, you must go to the hospital for further examination, so as not to delay the diagnosis and treatment of the disease.
Thank you for inviting me! Amoxicillin is an antibiotic, and it is a penicillin family antibiotic!
Is amoxicillin an antibiotic?
Amoxicillin is an antibiotic. Commonly used antibiotics include penicillin, azithromycin, erythromycin, amoxicillin and cephalosporin.
Does amoxicillin treat colds?
Hehe, amoxicillin is an anti-inflammatory drug, not a cold medicine, and of course it can't treat colds.
Can you eat amoxicillin for a cold?
Sure, but it depends on what kind of cold it is. The common cold can be treated by taking anti-cold drugs and antipyretic and analgesic drugs. If the flu symptoms are severe and you have a high fever, you can take amoxicillin and antipyretics.
Since Taobao data is an antibiotic, what is its efficacy?
Clinically, amoxicillin is widely used in respiratory tract infection, urinary tract and biliary tract infection, typhoid fever and so on caused by sensitive bacteria. , especially the bronchial secretory duct.
Amoxicillin is the most direct therapeutic drug for bronchitis patients, which is generally not easy to relapse after the course of treatment, and has a high curative effect and absorption on children's pneumonia.
Necessary warm tips:
Remember, penicillin allergy and amoxicillin allergy are forbidden!
Remember, only bacterial infections need antibiotics, and antiviral drugs are enough for common virus infections.
Remember, amoxicillin itself is not very toxic to human body. The main way of excretion is through urine. If you stop taking it, drinking water or glucose water often can make the drug excrete faster.
This is amoxicillin, remember its function.
Amoxicillin is an antibiotic.
Amoxicillin is one of the most commonly used semi-synthetic penicillin broad-spectrum β -lactam antibiotics, which belongs to penicillin and must be an antibiotic.
Try not to use antibiotics when children have a cold. The abuse of antibiotics will bring great harm to the body, and may even be irreversible. Antibiotics are the choice after a bad cold. If it is mild, don't take medicine if you can drink water, and don't take antibiotics if you can take ordinary medicine.
You can't take amoxicillin for toothache when you have a cold.
Amoxicillin is an antibiotic.
Antibiotics are drugs that specifically fight bacteria. Commonly used types are penicillins, cephalosporins, fluoroquinolones, aminoglycosides, macrolides, glycopeptides and so on.
The amoxicillin we usually use belongs to penicillin. Penicillins are a large class of antibiotics, the simplest of which is penicillin, and there are many others, such as oxacillin, piperacillin, amoxicillin and mezlocillin. Anything with the word penicillin belongs to penicillin. The reason why it is called XX penicillin is because the name of penicillin is penicillin, which translates to penicillin, so penicillin is penicillin. Since then, penicillin antibiotics have had the suffix "penicillin", so they are all called "penicillin", so the words "penicillin" are all penicillin antibiotics.
The antibacterial spectrum of amoxicillin is similar to that of ampicillin. It is a broad-spectrum antibiotic, which can kill many kinds of Gram-positive bacteria and Gram-negative bacteria. Mainly used to treat urinary system, respiratory system, biliary tract, intestinal infection, meningitis, endocarditis and so on. But the bacteria in these parts are only effective if they are sensitive to amoxicillin. If they are resistant or insensitive, they are ineffective.
Children can also use amoxicillin, which is relatively safe. But amoxicillin can cause anaphylactic shock and rash. A skin test must be done before use. If you are allergic to penicillin, you must disable it. Asthma patients and urticaria patients should also be used with caution. Of course, careful use does not mean that it cannot be used. It should be used under the guidance of a doctor. If penicillin such as amoxicillin is not suitable, cephalosporin can be considered.
But not all children should take amoxicillin when they have a cold, and they only need to use it if they are suspected or clearly infected by bacteria. Don't use antibiotics as soon as you have a fever, which will easily lead to drug resistance of bacteria and is not good for children.
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