Some people blush easily when they drink. Is there something wrong with their body?

It is too powerful to convince people of wine, but it is difficult. Liu Xiaomi must keep a glass of beer and cheer, "Okay." It is definitely enough. In less than three minutes, Liu Xiaomi's feelings were 33,354 people, But rednecks are thick. She thinks she is allergic to alcohol and because of this, she doesn't like drinking, she drinks a lot. Some people are hitting her, "Blush explains drinking!"

In recent years, it has been circulated online that drinking blush is actually an early warning to the body that he is at a relatively high risk of cancer. "Drink wine blush, be so serious and put it on," many young people don't believe it. However, Dr. Li Changqing from Qilu Hospital of Shandong University said that this is really not a joke and has a research certificate.

This is a blush, which may be the "appearance" of three major diseases! Expert: I am not a joke

Why are you blushing?

In order to drink blush, many people think that they are allergic to Liu Xiaomi, because these two people are very common. However, alcohol allergy, in addition to facial red symptoms, is often accompanied by these symptoms: 1. Itching of the face or body, 2. Rash, 3. Facial swelling, 4. Some may have nausea and vomiting, such as gastrointestinal angiography. If you are diagnosed with alcoholism, you need to strictly abstain from drinking and avoid other alcoholic foods.

In fact, alcohol allergy is a minority, and more people who drink blush are genetic mutations. This must be said from a range of populations in the human body where alcohol is present.

We know that the component of wine is alcohol, except water, which is ethanol. Alcohol enters the body through a three-step metabolic reaction:

First, alcohol needs acetaldehyde dehydrogenase to catalyze it into acetaldehyde.

In the second step, aldehyde dehydrogenase 2 (ALDH2) successfully turns it into relatively non-toxic acetic acid.

In the third step, acetic acid breaks down to form carbon dioxide and water into the excrement.

Among them, aldehyde dehydrogenase is a protein; aldehyde dehydrogenase 2 (ALDH2) refers to the gene responsible for acetaldehyde dehydrogenase.

Aldh2 is usually found in Westerners, but many Asians have one or two variants of the Aldh2 gene. Carrying the defective gene results in the inability to metabolize it efficiently, and acetaldehyde will then accumulate in the liver and blood, causing capillaries to swell, causing reactions such as blushing, nausea, and skipping speed. Data exist to suggest that there may be a third gene in Chinese that is defective in the production of active acetaldehyde dehydrogenase 2.

How to determine if there are any ALDH2 gene mutations? Through two questions, it can roughly judge:

Question 1: Will there be an immediate red reaction after drinking a glass of beer exceeding 180 ml?

Question 2: If you have a red reaction, do you have beer face?

If the answer to either of the above two questions is "yes", it indicates that you may be a carrier of a defective ALDH2 gene. What disease is easy to drink?

The red face reaction after drinking alcohol is a common cause of the inability to decompose acetaldehyde in the body. The reason is the mutation of the Aldh2 gene. As long as you don't drink alcohol, it seems to have no adverse effects on the body. However, following some research, scientists have discovered that drinking blush may have potential health risks.

1. High blood pressure

Excessive drinking is one of the risk factors for high blood pressure. South Korea's South Central National University found that a study of 1,763 men who were prone to blushing and even a small amount of alcohol could raise high blood pressure. People who drank 4 drinks a week were at risk for high blood pressure. In people without blushing, just 8 or more cups per week increased the risk of high blood pressure. Therefore, scientists suggest that people who drink alcohol will pay more attention to drinking control to prevent high blood pressure.

Due to ALDH2 mutation, alkaline decomposition caused by alcohol-containing metal hydroxyl groups, as well as large accumulation in the liver and blood, not only causes skin tendencies, inflammation, but also causes certain damage to the liver, thereby causing alcohol It can cause hemorrhagic liver damage and cerebrovascular disease.

2. Esophageal cancer

About drinking facial easy food, esophageal cancer has been circulating. As early as 2009, studying Brooke et al.

It was found that if you drink alcohol, if you don't stop your face, then they will increase the risk of respect cancer rather than drinking alcohol. Later, related studies in Japan and Taiwan showed that two-thirds of alcoholic Aldh2 mutants may be present in esophageal cancer patients.

Li Changqing said that drinking blush is because acetaldehyde has not been decomposed, which may damage human DNA, and any factor that repeatedly damages DNA may cause cancer.

As mentioned before, the Aldh2 mutation can be a change, and the blush reaction should be light; it can also be both changes, and the blush reaction should be severe. According to Chinese scholars, in 2010 and 2011, it was found that drinkers with ALDH2 mutations are a high-risk group for esophageal cancer, and the risk of esophageal cancer will not increase in ALDH2. That is, drink a little red, but drink it more carefully. The reaction to drinking red wine is mild. Don't expect to improve your alcohol intake through "exercise". This behavior will put you closer to cancer.

3. Gastric cancer

Research on Aldh2 gene mutations. A study by the University of Tokyo in Japan found that people carrying Aldh2 gene mutations will increase the risk of gastric cancer even if they drink a small amount.

Alcohol is an irritant to the stomach, especially a large amount of drinks, or drinking a large amount is enough to cause gastric bleeding. Chronic damage in the stomach may be buried in cancer. At present, high risk factors for gastrointestinal cancer are known, including excessive drinking, Helicobacter pylori infection, overeating, long-term smoke, fumigation, and mental stress.