Question How big is the vaccine? Read the answer

On March 18, 2016, some media broke the news that since 2010, Pang Mouwei and her daughter in Jinan, Shandong Province were suspected of illegally selling vaccines and illegally purchased 25 kinds of second-class vaccines for children and adults. Strict cold chain storage and transportation were sold to 18 provinces and cities across the country, with the amount involved reaching 570 million yuan. On March 19, 2016, the Shandong Provincial Food and Drug Administration announced: Based on the information obtained by the Jinan Food and Drug Administration in assisting the public security organs in detecting the illegal vaccine operation case of Pang Mou and others, *** sorted out the vaccine and drug supply to Pang Mou and others. There are 107 online clues for biological products and 193 offline clues for purchasing vaccines and biological products from Pang and others, involving 24 provinces and cities across the country. The 24 provinces and cities involved are: Anhui, Beijing, Fujian, Gansu, Guangdong, Guangxi, Guizhou, Hebei, Henan, Heilongjiang, Hubei, Jilin, Jiangsu, Jiangxi, Chongqing, Zhejiang, Sichuan, Shaanxi, Shanxi, Shandong, Hunan, Liaoning, Inner Mongolia, and Xinjiang. On March 20, 2016, the Shandong Food and Drug Supervision Department verified the list of vaccine varieties seized in Pang’s illegal vaccine operation case provided by the police and found that there were 12 types of vaccines, 2 types of immunoglobulins, and 1 therapeutic biological product. kind. The specific list is as follows: There are no Category 1 vaccines among the 12 vaccines, and all are Category 2 vaccines: Freeze-dried human rabies vaccine (Vero cells), polio fire-extinguishing vaccine, Haemophilus influenzae type B conjugate vaccine, live attenuated meningococcal meningitis B Vaccine Mumps live attenuated vaccine Freeze-dried Japanese encephalitis inactivated vaccine (vero cells) Recombinant hepatitis B vaccine (CHO cells, Hansenula yeast) Group A and C meningococcal conjugate vaccine ACYW135 meningococcal polysaccharide vaccine Chickenpox Live attenuated vaccine Oral live rotavirus vaccine Hepatitis A inactivated vaccine (human diploid cells) 2 immunoglobulins: rabies patient immunoglobulin Hepatitis B human immunoglobulin 1 therapeutic biologic: bacterial lysate Problems What are the problems with vaccines? Vaccines, children must be vaccinated from birth! It stimulates the human immune system through the "antigens" contained in it to produce antibodies to protect human health. The core of any vaccine is its "antigen" part. In order to ensure the biological activity of the antigen, most vaccines should be stored in a constant temperature environment of 2 to 8°C. Whether it is high temperature, freezing, or even long-term light exposure, it may affect the effectiveness of the vaccine and even cause the vaccine to become inactive and ineffective. Some of the vaccines sold by Pang Mouwei are expiring vaccines, and the warehouse where the vaccines are stored has only two freezers for freezing ice cubes. Pang Mouwei placed the entire vaccine in the warehouse without refrigeration. When shipping to the downstream line, he divided the vaccine into foam boxes, put it in ice cubes, wrapped it and sent it to all parts of the country through express companies. At the scene where Pang Mouwei and her daughter were arrested, it was raining lightly and the temperature was several degrees Celsius lower than usual. However, the thermometer in the warehouse where the vaccines are stored shows that the room temperature is close to 14°C. The biggest cause of panic in the news exposure of illegal vaccines is that the vaccine failed due to lack of cold chain storage and was sold everywhere. Question Are vaccines fatal? Wang Yuedan, deputy director of the Department of Immunology at Peking University School of Medicine, commented, "This is killing people." So is injecting a problematic vaccine really fatal? The primary risk when vaccinating vaccines that have not been stored in the cold chain at 2°C-8°C or expired vaccines is ineffective immunity. Invalid vaccines will cause the human body to be unable to obtain normal immunity. The vaccines involved this time include "meningitis for children, chickenpox" , vaccines for polio and influenza for adults, rabies, hepatitis A” and more. If you are injected with an ineffective vaccine and therefore do not have the immunity you should have, you will of course face a higher possibility of death! For example, fatal infectious diseases such as rabies can be avoided by vaccination. However, vaccination with defective vaccines results in ineffective immunity, and the recipients may become infected and die. Should you vaccinate your baby? Parents who have doubts can directly choose a reliable institution for re-vaccination, or they can wait for vaccination. After the case is further clarified, they can compare the vaccination points with the problems found and the vaccination history of their children to decide whether to vaccinate accordingly. of reseeding. Based on the principle of caution, if parents are still worried about the current Class II vaccines, then just wait. This time delay will generally not affect the effectiveness of the vaccine.

It’s better to wait until things become clearer and try to avoid those problematic vaccines. In addition, formal epidemic prevention centers in first-tier cities, where vaccine management has always been strict, basically do not have to worry about problematic vaccines. You can choose an epidemic prevention institution that you think is reliable enough for vaccination. Who is the initiator? As the primary suspect in the case, Pang Mouwei had a "record" of illegally operating vaccines. 47-year-old Pang Mouwei was originally a doctor at Mudan People's Hospital in Heze City, Shandong Province, and ran the Dongcheng District Epidemic Prevention Clinic in Mudan District of the city. In 2009, Pang Mouwei was sentenced to 3 years in prison, suspended for 5 years, and fined 500,000 yuan for illegally operating Class II vaccines for human use, involving 4.89 million yuan alone. However, while on probation, Pang "returned to his old business" and made his illegal vaccine business bigger and more rampant. This time, a total of 25 types of vaccines for children such as meningitis, chickenpox, and polio, as well as vaccines for adults such as influenza, rabies, and hepatitis A, and more than 20,000 vaccines in more than 100 boxes were seized in Pang's rented warehouse. Since 2010, for more than five years, Pang Mouwei, her mother and her daughter purchased influenza, hepatitis B, and rabies at low prices from more than 70 pharmaceutical company salesmen or vaccine dealers in more than 10 provinces and cities, including Shaanxi, Chongqing, and Jilin. Waiting for 25 kinds of human vaccines (some vaccines on expiration date), and then selling them at a higher price to 247 people in 18 provinces, municipalities, and autonomous regions, including Hubei, Anhui, Guangdong, Henan, and Sichuan. The cumulative transaction amount reached 570 million yuan, including 260 million yuan in payments and 310 million yuan in receipts. Why was Pang Mouwei able to commit such a large-scale crime? Why was he only sentenced to 3 years in prison and 5 years suspended when he was first involved in the case? Why, instead of repenting during the probation period, did he intensify his behavior and commit even crazier behaviors? How much harm have problematic vaccines caused to society, families, and children themselves in the past five years? What will happen to the vaccines that have been leaked? We will follow up on the report further.