What caused the thrombin time (TT) to increase to 18.2see? Will there be any disease? (The reference range is 1 1.0- 17.8)

Alias:

TT； Tankcrewtrainer

Introduction to thrombin time:

Thrombin time is a simple test to detect the function of coagulation, anticoagulation and fibrinolysis system, especially to know whether fibrinogen in plasma contains enough fibrinogen and whether the result is normal.

Normal thrombin time:

16 ~ 18s； More than 3 seconds beyond the normal control is abnormal.

Clinical significance of thrombin time;

(1) Prolongation: Fibrinogen decreased.

Congenital: congenital absence (low fibrinogen), abnormal fibrinogen, etc.

Acquired: liver cirrhosis, hepatitis, disseminated intravascular coagulation (DIC), fibrin degradation products (FDP), etc.

(2) Shortening: increase of fibrinogen (infection, inflammation, cancer, third trimester, etc. )

Thrombin time-related diseases:

1, β thalassemia (β thalassemia; β -marine anemia; β -globin production disorder anemia)

2. Severe liver disease leads to acquired coagulation factor abnormality.

3. Hemorrhagic diseases (hemorrhagic diseases)

4. Primary Fibrinolysis (Primary Fibrinolysis)

5, respiratory muscle fatigue

6. Pregnancy complicated with thrombotic thrombocytopenic purpura (pregnancy complicated with thrombotic thrombocytopenic purpura)

7. Minimal invasive carcinoma of the cervix (early invasive carcinoma of the cervix; Early cervical interstitial infiltrating carcinoma; Cervical microcarcinoma; Invasive carcinoma under cervical endoscope; Cervical carcinoma in situ with tiny infiltration focus; Local invasive carcinoma of cervix)

8. Acute pancreatitis in children

9, children's disseminated intravascular coagulation (disseminated intravascular coagulation; Diffuse intravascular coagulation; Diffuse intravascular coagulation)

10, hyperthyroidism in children (hyperthyroidism; Hyperthyroidism; Hyperthyroidism; Hyperthyroidism; Hyperthyroidism)

1 1, acute pyelonephritis

12, disseminated intravascular coagulation (disseminated intravascular coagulation; Consumptive coagulopathy; Defibrinogen syndrome; Consumptive coagulopathy)

13, neonatal disseminated intravascular coagulation (neonatal disseminated intravascular coagulation; Neonatal disseminated intravascular coagulation)

14, scleredema neonatorum (frostbite syndrome; Neonatal frostbite; Neonatal sclerosis; Frostbite syndrome; Neonatal scleredema)

15, fulminant liver failure (fulminant liver failure)

16, epidemic hemorrhagic fever (hemorrhagic fever with renal syndrome; Hemorrhagic nephritis nephropathy; Korean hemorrhagic fever; Epidemic nephropathy; Hemorrhagic nephropathy nephritis; Hemorrhagic fever nephrotic syndrome; Hemorrhagic fever with renal syndrome; HFRS； Korean hemorrhagic fever; Epidemic nephropathy; Epidemic nephropathy)

17, fungal stomatitis (oral candidiasis; Thrush; Fungal stomatitis; Mugai; Fungal stomatitis; Soor fungal stomatitis; Thrush; Oral candidiasis)

18, rickettsia rickettsia spot fever (rickettsia rickettsia spot fever; Rocky mountain spotted fever; Rocky mountain spotted fever; Rocky mountain spotted fever; ; Tick-tock heat transfer; Tick-borne typhus; Rocky mountain spotted fever; Typhus, tick-borne; Fibre Manchada; Fiebre petequial rosacea; Sao Paulo typhus)

19, systemic amyloidosis (amyloidosis; Amyloidosis; Amyloidosis; Amyloidosis; Amyloidosis)

20. Postmenopausal cervical cancer

2 1, green monkey disease (African hemorrhagic fever; Marburg-Ebola virus disease; Marburg virus disease; African hemorrhagic fever)

22, septic shock in the elderly (septic shock in the elderly; Septic shock in the elderly; Septic shock in the elderly; Senile septic shock)

23. Hypothyroidism in the elderly (hypothyroidism in the elderly; Elderly hypothyroidism; Hypothyroidism in the elderly; Hypothyroidism in the elderly; Elderly hypothyroidism)

24, hepatomegaly (hepatomegaly; Hepatomegaly; Hepatomegaly; Giant liver disease)

25, cirrhosis (cirrhosis; Cirrhosis; Cirrhosis)

26. Premature separation of placenta (placental abruption; Early placental abruption; Placental abruption; Placental abruption; Placental abruption)

27, hemophilia B (plasma thrombokinase component deficiency; Hereditary factor ⅸ deficiency; Christmas disease; Hemophilia b)

28, hemophilia A (hemophilia A)

29, thrombotic thrombocytopenic purpura (thrombotic thrombocytopenic purpura)

30. hereditary coagulation factor V deficiency

3 1, severe nosocomial pneumonia (nosocomial pneumonia; Hospital pneumonia; Hospital acquired pneumonia; NP)