How to join Chinese bone marrow bank?

18-45 years old, in good health and willing to donate hematopoietic stem cells, you can contact the local Red Cross Society (a provincial branch of the database) or register in a local blood donation car (station). Or go to the local third-class hospital to register.

6-8 ml blood was taken from the designated place, and after HLA typing test, all relevant data were entered into the computer database of China Bone Marrow Bank. In this way, you become a volunteer to donate hematopoietic stem cells.

The whole process of donating peripheral blood hematopoietic stem cells;

The process of donating hematopoietic stem cells can be divided into the following ten steps.

(1) Application for preservation: fill in the registration form for donating hematopoietic stem cells, and leave blood samples for HLA testing. Those who meet the storage conditions and wish to donate hematopoietic stem cells should first go to the blood donation point or place designated by the hematopoietic stem cell donor database management center and its branches that have the registration conditions for donating hematopoietic stem cells.

Fill in the Consent of Voluntary Donation of Hematopoietic Stem Cells and the Registration Form of Hematopoietic Stem Cell Donation and related materials, and leave a blood sample (about 8 ml) for HLA typing and other items. Usually: at the same time of blood donation, you can apply for registration to donate hematopoietic stem cells. When applying for registration, in addition to physical and mental health and age, you need to meet the storage conditions.

It is also necessary to confirm that he has a detailed understanding of blood science knowledge and common sense of donating hematopoietic stem cells at the time of application, and he can fulfill his donation promise without hesitation after careful consideration and matching.

(2) Storage of information and test data: those who intend to donate hematopoietic stem cells fill in the Consent of Voluntary Donation of Hematopoietic Stem Cells, the Registration Form of Hematopoietic Stem Cell Donation and related materials, and leave blood samples for HLA typing and other items, and then the database management center of hematopoietic stem cell donors and its branches will manage them.

Blood samples will be sent to the designated laboratory of China Bone Marrow Bank as soon as possible for HLA typing and other items testing, and then the qualified volunteer donor information and HLA typing test data will be entered into the national volunteer donor database for donating hematopoietic stem cells, waiting for patients who need hematopoietic stem cell transplantation to get back the matching.

Since then, the applicant has truly become a voluntary donor of hematopoietic stem cells in China Bone Marrow Bank. After that, the voluntary donors of hematopoietic stem cells should keep the updated telephone number, QQ number, e-mail address and mailing address with the database management department.

Keep in touch smoothly. In a sense, whether and when the information of voluntary donors can be donated after storage depends on fate and luck.

(3) Relocation after preliminary HLA matching: When a voluntary donor is found in the hematopoietic stem cell donor database to match the HLA of a patient who needs bone marrow transplantation, the relevant staff of the database management center and its branches will quickly contact the matching voluntary donor to explain the situation. If it is confirmed that the physical and mental condition of the voluntary donor is in line with the commitment to continue donating.

We will mobilize them, explain the donation collection methods, possible problems and solutions in the collection process, and hope that they will continue to fulfill their commitment to donate hematopoietic stem cells and cooperate with their work.

(4) Take blood samples again for high-resolution matching compound test: When it is confirmed that the voluntary donors meet the conditions of continuous donation and are willing to fulfill the commitment of donating peripheral blood hematopoietic stem cells after mobilization again, professionals will take blood samples again, and then send the blood samples to the high-resolution matching laboratory designated by China Bone Marrow Bank for HLA high-resolution matching compound test.

When the high-resolution matching compound test determines that the HLA of the volunteer donor matches the HLA of the patient who needs hematopoietic stem cell transplantation and meets the requirements of transplantation conditions, the volunteer donor is invited to sign the donation consent and donation agreement, and the database management center and its branches will arrange for the pre-harvest physical examination in the designated hospital.

(5) Pre-harvest physical examination: For the voluntary donors of hematopoietic stem cells who meet the high-resolution matching compound test, if they feel healthy and are willing to continue to fulfill their commitment to donate peripheral blood hematopoietic stem cells, necessary physical examinations will be arranged for the voluntary donors of hematopoietic stem cells, and the physical and mental conditions of the voluntary donors will be evaluated by specialists.

After evaluation, it is confirmed that the physical and mental conditions of voluntary donors meet the requirements of donating hematopoietic stem cells. China Bone Marrow Bank Management Center will notify the hospitals that apply for matching for voluntary donors and patients, and then the hospitals, databases and collection hospitals that transplant hematopoietic stem cells for patients will formulate collection and transplantation plans.

(6) Hematopoietic stem cell mobilization agent injection: After the collection and transplantation plan is made, the transplantation hospital, the database management center and its related institutions, and the collection hospital should prepare for the collection and transplantation simultaneously as planned.

Those who intend to donate peripheral blood hematopoietic stem cells need to receive subcutaneous injection of hematopoietic stem cell mobilization agent (also known as inducer, granulocyte colony stimulating factor, G-CSF) in the collection hospital or collection center 4-5 days before collection to induce a large number of red bone marrow hematopoietic stem cells to enter peripheral blood, and accept the monitoring and supervision of the collection hospital.

In the United States, the first injection of mobilization agent was in a hospital or clinic, and there was no problem after the first injection. Donors inject other injections at home (just like diabetics inject insulin themselves), and donors go to the collection center to donate on the morning of collection.

(7) Collection of peripheral blood hematopoietic stem cells: When the density of hematopoietic stem cells in peripheral blood reaches an ideal state (generally on the fifth day after injection of hematopoietic stem cell mobilization agent), collection begins. The process of collecting hematopoietic stem cells, like blood donation, is to puncture venous vessels at the elbow of the donor's arm.

Then, the blood flowing in the blood vessels is separated and peripheral blood hematopoietic stem cells are extracted from it. The process is the same as that of collecting platelets by blood donation machine, except that mobilization agent and needle need to be injected and stay in the blood vessel for a longer time (the whole process is about 3-5 hours), and more blood is processed (separated).

The amount collected depends on the weight of patients and donors and the number of hematopoietic stem cells needed for transplantation. If the patient needs fewer hematopoietic stem cells and the donor is heavier, it is enough to collect hematopoietic stem cells once.

If the number of hematopoietic stem cells collected at one time cannot meet the needs of patients, hematopoietic stem cells will be collected again the next day, and the suspension of hematopoietic stem cells will be about 200 ml each time. Usually, each therapeutic dose of hematopoietic stem cell suspension contains 5- 10g hematopoietic stem cells.

(8) Post-harvest observation: after the needle is pulled out after collection, continue to observe and rest according to the doctor's requirements. After resting for 2 hours, you can relax around the blood collection room without abnormal symptoms. Other precautions are basically the same as donating platelets collected by machine.

(9) Follow-up: review the physical examination and follow-up according to the doctor's requirements and prescribed items.

(10) Commendation, friendship and voluntary service: When holding charitable activities such as donating bone marrow and hematopoietic stem cells, we should respect honor and downplay property. In 2008, the Ministry of Health, the China Red Cross Society and the Ministry of Health of the General Logistics Department of the People's Liberation Army of China commended Chinese mainland for donating hematopoietic stem cells (including bone marrow donor) over the years.

Every donor of hematopoietic stem cells has won the National Award for Free Donation of Hematopoietic Stem Cells. Since then, hematopoietic stem cell donation has been formally incorporated into the national voluntary blood donation recognition system.

Under normal circumstances, the relevant state departments will hold a national commendation meeting for blood donation every two years. All localities will also create conditions, take advantage of various opportunities to commend hematopoietic stem cell donors, and organize corresponding networking parties, seminars and exchange activities to promote the spirit and behavior of loving their posts and dedication.

Bone marrow donor:

Every bone marrow bank in the world has a certain proportion of hematopoietic stem cell donors who go back on their word and lose it when donating. The effective way to reduce the rejection rate and the rate of repentance is that every volunteer donor should carefully understand the knowledge of blood science and the common sense of donating hematopoietic stem cells when registering. Familiar with the donation process.

Do a good job in the ideological work of spouses and immediate family members, and then fill in the registration form of voluntary donation of hematopoietic stem cells to ensure that patients who need hematopoietic stem cell transplantation can donate without hesitation when matching.

Donating hematopoietic stem cells doesn't cost anything.

There is no need to pay any fees for applying for registration as a voluntary donor, and if one day the patient is successfully matched, the donor does not need to pay any fees. These expenses are composed of government lottery public welfare fund, donations from organizations and individuals, and collection expenses paid by the donee according to national standards.

Reference to the above contents: China Bone Marrow Bank-Notes for Donating Hematopoietic Stem Cells after Joining China Bone Marrow Bank