Can AIDS be detected in the incubation period?

Aids can be detected in the incubation period. HIV antibody testing is a common AIDS screening method. Positive means infection, negative means no infection. This judgment is the "common sense" of most people on AIDS testing.

However, a recent paper published by Peking Union Medical College Hospital in an international professional academic journal subverts this "common sense". This paper published the first confirmed AIDS patient with negative HIV antibody test but positive HIV "nucleic acid test" in China. This is also the world's first case of adult HIV-negative AIDS complicated with pulmonary Kaposi's sarcoma.

The patient's HIV antibody testing and confirmation tests in many hospitals in many places failed to make a clear diagnosis. Later, through nucleic acid testing in Union Medical College Hospital, it was found that there was a highly replicated HIV virus in the body, which was diagnosed as the late stage of AIDS. This case reveals the important value of HIV nucleic acid detection in AIDS diagnosis.

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With the development of biotechnology, people pay more and more attention to nucleic acid detection. It can directly detect HIVRNA and detect HIV infection before serological changes are found, which is more sensitive than P24 antigen detection. Simply put, after the virus infects the human body, it can generally be found through a series of tests, and the virus nucleic acid can be detected at the earliest.

The existing serological detection methods such as enzyme-linked immunosorbent assay (ELISA) detect antigens or antibodies, while nucleic acid detection technology detects viral nucleic acids, so virus infection can be found earlier. It takes about 42 days to detect HIV in normal blood, and HIV nucleic acid detection shortens the "window period" of HIV detection to 1 1 day.

Nucleic acid detection technology can shorten the "window period" of hepatitis B and hepatitis C virus detection from 50 days and 72 days to 25 days and 59 days respectively. Therefore, blood safety can be better guaranteed.

Zhongxin. com-Sheikh found that the first negative AIDS patient in China was positive for nucleic acid test.

Baidu Encyclopedia-HIV nucleic acid detection