Matters needing attention of hemoperfusion device:

1 No need to sterilize again before use. Pay attention to check whether the casing of the perfusion device is damaged or expired. If so, it is forbidden to use.

2 Don't drain the perfusate from the perfuser, so as not to discharge it again (press 6. 1.2).

3 This product is fragile, so it should not be tightened too hard; When exhausting, it is forbidden to knock with metal instruments to prevent damage.

Closely observe the changes of patients' temperature, pulse, respiration and blood pressure, pay special attention to the decrease of blood pressure caused by the decrease of blood volume at the initial stage of perfusion, and take corresponding measures. 5 In order to prevent fever and chills during perfusion, dexamethasone 5mg- 10mg can be given intravenously at the beginning of perfusion.

At the beginning of perfusion, some patients may have chills due to blood loss and low ambient temperature. Once it happens, it can be treated symptomatically to avoid condensation.

Coagulation will greatly reduce the perfusion effect and even be forced to terminate perfusion. The reasons are as follows: first, the amount of heparin is insufficient (heparinization of perfusion device and heparinization of whole body) and the heparinization time of perfusion device is short; Second, the blood flow is insufficient, and it is easy to coagulate below 100ml/min; Third, the ambient temperature is low. When arterial pressure rises, find out the reason and deal with it in time. If necessary, replace the perfusion device to continue perfusion.

Due to the decline of platelets in different degrees during HP treatment, platelets should be checked routinely if secondary HP treatment is needed.

It is suggested that plasma perfusion should be used for patients with severe liver disease accompanied by coagulation disorder, such as severe hepatitis and liver failure, so as to reduce the risk of thrombocytopenia.

When 10 hemoperfusion is combined with hemodialysis and hemofiltration, the perfusion device should be connected in series in front of the dialyzer, otherwise coagulation will easily occur.

1 1 In order to prevent blood coagulation, patients with hypercoagulability can be washed quickly every 30 minutes during perfusion, and the perfusion device can be rotated.

12 if conditions permit, low molecular weight heparin can be used for systemic heparinization.

13 has no bubble detection. When only one blood pump is used for hemoperfusion, it should be closely observed to prevent air from entering the patient's body.

14 Very few patients should immediately stop perfusion and give symptomatic treatment once they have allergic phenomena within a few minutes of perfusion.