Background: Many people are weak and cannot resist the tendency to avoid problems. They do not want to face problems, but just avoid them. People avoid problems in different ways, and some choose to d

Background: Many people are weak and cannot resist the tendency to avoid problems. They do not want to face problems, but just avoid them. People avoid problems in different ways, and some choose to drink alcohol. Alcoholism may be due to genetic damage. Many people have the bad habit of alcoholism. Drinking a lot of alcohol not only has adverse effects on the body, but also easily leads to family conflicts and is one of the unstable factors in society. But why do some people become alcoholics? According to Xinhua News Agency, genetic experts from the University of Kuopio and the University of Turku in Finland have discovered through long-term research that a mutation in a gene in the human body can lead to excessive drinking and alcoholism. This gene mutation can cause neuropeptide protein defects in the central nervous system of the human body, causing people to have a depressive reaction. This melancholy and unhappy mood often makes people have to vent their depression with the help of something in a cup. The research results of Finnish experts show that Finnish men with abnormal amounts of neuropeptides tend to be greedy and drink significantly more than normal people. In addition, defects in neuropeptide proteins can have broader effects on their eating habits. Popova and Ivanova, experts from the Institute of Cell and Genetics of the Russian Academy of Sciences, believe that damage to the monoamine oxidase gene may be the main reason why some alcoholics binge drink. Ordinary people will experience intoxication such as numbness of the limbs and drowsiness after drinking a certain amount of alcohol. However, alcoholics usually drink a lot and are not prone to these intoxication states. According to the Russian "Izvestia" report, Popova and Ivanova discovered during an alcoholism experiment on mice that when the mice's monoaminooxidase gene was damaged and unable to function, the mice would drink excessively. Further research on the parts of the body affected by alcoholism shows that the monoamino-oxidase gene can produce a protein that controls the concentration of neuromediators such as serotonin, dopamine, and norepinephrine in mice. Therefore, ordinary mice consume a certain amount of alcohol. Afterwards, the nervous system will be excited first, then inhibited, and then appear drunk. In mice with damaged monoamino-oxidase genes, the concentration of neural mediators was much higher than in normal mice. Therefore, after consuming large amounts of alcohol, the genetically damaged mice were still able to remain in a state of euphoria for long periods of time without getting drunk. In addition, this kind of mouse is also very aggressive. Main hazards: Alcoholism is the culprit of causing, inducing, and exacerbating oxidative stress diseases such as type 2 diabetes, hypertension, dyslipidemia (such as high triglycerides), gout, and other diseases. For ninety-seven percent of people, alcohol is the primary means of social interaction—a form of relaxation, relief, and an escape from the stresses of daily life. There's no harm in it, is there? What's more, you may have read that a little stiff drink is good for you. But alcohol's benefits aren't all they're cracked up to be. Sure, a glass of red wine every night has been proven to be good for your heart, but more than two and you start destroying your liver, dehydrating your skin, and killing brain cells that are in short supply. This is what alcohol does to the body: Adds fat. Makes more fat. Three large glasses of wine and a snack of chips/pizza/kebab on the way home will leave you with 0.25 kilograms (1/2 pound) of fat on your body. Because your body will first consume the useless calories (contained in alcohol) and then store the rest as fat, which will affect vision and blur your vision. Alcohol paralyzes your eye muscles, which means your eyes can't focus and calculate distances correctly. At the same time, it also disrupts the normal operation of the brain's coordination system, which means you are more likely to fall. Osteoporosis Alcohol and osteoporosis (brittle bone disease) are linked because heavy drinking causes the body to lose nutrients at an accelerated rate, which means you are losing bones. Bone fragility - slows down the activity of bone-growing cells in the body, harming menstruation. Women who drink a lot of alcohol are more likely to experience premenstrual discomfort due to the high sugar content of alcohol. This can mess up your blood sugar levels and rob you of the nutrients you need to combat PMDD symptoms. Ruins your skin Alcohol can make you look older because heavy drinking dehydrates you and your skin loses its elasticity, causing it to age faster, causing more wrinkles and basically making you look like an old witch.Increased pain Alcohol is a depressant, which means it will initially take you to a near-perfect pink state of supreme illusion, and then suddenly pull you back to the present, followed closely by depression. Cirrhosis of the liver Also known as cirrhosis, when liver cells die, the liver tissue begins to form a hard scab, and the liver gradually hardens. This is a direct result of chronic alcoholism, and if you've been drinking almost every day since your twenty-first birthday, it's time to call it quits. Thankfully, the liver has the ability to repair itself, but only if you give it enough time to do so. According to the human aging (oxidation) timetable, the liver should only start to age after the age of 70. However, because people’s alcoholism directly affects the liver, the life span of alcoholics will be greatly reduced. According to the theory of "Yellow Emperor's Internal Classic", the liver system mainly stores blood, and heavy drinking every night (especially from 1:00 to 3:00 in the morning is the liver's "duty" time, when the blood should return to the liver for filtration), causing the blood to flow retrograde throughout the body. Drinking during the day is more harmful and causes the liver to age (oxidize) faster. If liver cirrhosis occurs and the effects are irreversible, in theory, antioxidants such as vitamin E, astaxanthin, and β-carotene can only be used to protect the "remaining cells" of the liver and extend life. First, women get drunk more easily than men of the same weight because our livers produce less of the enzymes that help break down alcohol. Moreover, the fat content of women's bodies is 10% higher than that of men (this is caused by genetic inheritance, so don't panic), but the water content is less than that of men, which means that we cannot handle alcohol as easily as men. question. The Harm of Alcoholism A large number of clinical trials have confirmed that ethanol in alcohol causes the most direct and greatest damage to the liver. It can cause degeneration and necrosis of liver cells. Drinking a large amount at one time will kill a large number of liver cells and cause a sharp increase in transaminases. Long-term drinking can easily lead to alcoholic fatty liver, alcoholic hepatitis, and even alcoholic cirrhosis. According to a scientific research report from the Disaster Prevention Research Office of the Shanghai Institute of Environmental Economics, in the past seven years, the number of patients with alcohol poisoning caused by long-term drinking of large amounts of strong liquor has increased by 28.5 times, and the number of deaths has increased by 30.6 times. It affects digestion. Drinking alcohol can cause stomach problems. Alcohol has a strong stimulant effect on the mucous membrane of the digestive tract. Therefore, drinking a lot of alcohol may make your chest and throat feel disgusting and burning, make it difficult to swallow, and even cause nausea or vomiting. Acid reflux. Because alcohol can cause inflammation or even ulcers on the inside of the digestive tract. Effects on the mucosa of the esophagus and stomach Alcohol has a great impact on the mucosa of the esophagus and stomach, causing mucosal congestion, swelling and erosion, leading to esophagitis, gastritis, and ulcer disease. Alcohol is mainly metabolized in the liver and has a particularly great impact on the liver. The incidence of liver cancer is directly related to long-term alcohol abuse. Studies have shown that 75% of people who drink an average of 160 grams of liquor a day will have severe liver effects within 15 years, and may also induce acute cholecystitis and acute pancreatitis. Increased blood pressure. Drinking alcohol increases blood viscosity. Causes cardiovascular disease, making heart attacks more likely because alcohol increases the levels of bad fats called triglycerides in the blood. Just drink a little more than the minimum amount, even as little as after work. A few cups can raise your blood pressure levels. If you drink heavily on a regular basis, your blood pressure will remain high and will not get better until you stop drinking. Inducing stroke Alcohol affects fat metabolism and increases blood cholesterol and triglycerides. Drinking a lot of alcohol will increase your heart rate and blood pressure, which can easily lead to stroke. Long-term drinking can also cause fatty degeneration of the heart, seriously affecting the normal function of the heart. Alcoholic psychosis: When the alcohol concentration in the blood reaches 0.1, people will be emotionally impulsive; when it reaches 0.2~0.3, it will cause people to behave abnormally; long-term alcohol abuse will lead to alcoholic psychosis. Nutritional imbalance Long-term alcohol abuse can also cause nutritional imbalance in the body and cause multivitamin deficiencies. Because alcohol does not contain nutrients, regular drinkers will lose their appetite and eat less, which will inevitably lead to a lack of multiple nutrients, especially the lack of vitamin B1, vitamin B2, and vitamin B12, which will also affect the absorption of folic acid.

Impact on the Fetus Harm to the Fetus Female alcoholism is more harmful. Studies have found that women's brains shrink faster than men's after becoming dependent on alcohol. Alcohol also has toxic side effects on sperm and eggs. Whether the father or the mother drinks alcohol, it will cause adverse consequences such as developmental malformations and mental retardation in the next generation. If pregnant women drink alcohol, alcohol can enter the fetus through the placenta and directly poison the fetus, affecting its normal growth and development. Families where the husband is a frequent alcoholic have a much higher average number of abortions than other families. Harm to Society Alcoholism is also extremely harmful to society because alcoholism is a pathological or abnormal behavior that can constitute a serious social problem. Alcoholics usually regard alcoholism as an important way and way to vent the strong psychological potential energy caused by inner conflicts and psychological contradictions. Alcoholics often turn to alcohol in order to eliminate worries and relieve psychological feelings such as emptiness, timidity, guilt, and failure. If the whole society turns a blind eye to the phenomenon of alcoholism and does not take effective measures to dissuade it, drunkards may endanger social security and cause us to encounter theft, murder, divorce after domestic violence, etc. This is not sensational. There are as many as 4 million cases of alcohol-related accidents filed in our country every year; 100,000 people die in car accidents across the country every year, and more than one-third of traffic accidents are related to alcohol abuse and drunk driving. Affects Muscles Long-term alcohol abuse can lead to muscle weakness. American researchers recently reported in The Journal of Cell Biology that they have cracked the secret of how alcohol abuse harms the body at the molecular level. Chronic alcohol abuse affects a key mitochondrial protein, preventing mitochondria from repairing themselves and affecting the ability of muscles to regenerate. Mitochondria mainly provide energy to human cells. In cells of many tissues, damaged mitochondria repair themselves by fusing with other mitochondria to exchange materials. Skeletal muscles also rely on mitochondria to provide energy, but most researchers previously believed that skeletal muscles do not have this self-repair mechanism. The reason is that the muscle cell fibers are very crowded and the mitochondrial space is over-squeezed, so that there is basically no chance for contact between mitochondria. Fusion. To investigate whether mitochondria in muscles could indeed fuse and regenerate, researchers at Thomas Jefferson University in the United States first devised a method to label mitochondria in the skeletal muscles of experimental mice with two different colors. Specifically, the researchers created a mouse model whose mitochondria consistently expressed red, but mitochondria damaged by lasers turned green. The observations showed that green mitochondria not only mixed with red mitochondria, exchanging contents, but were also able to move to other areas where only red mitochondria had previously existed. The researchers say the results are exciting because they "demonstrate for the first time that mitochondrial fusion occurs in muscle cells." Further research showed that a protein called Mfn1 plays the most important role in mitochondrial fusion in skeletal muscle cells, and long-term alcohol abuse can destroy it. In experimental mice that drank alcohol regularly, Mfn1 levels were reduced by as much as 50% and mitochondrial fusion was significantly reduced, thereby affecting muscle regeneration. Once Mfn1 levels return to normal, mitochondrial fusion also returns to normal. Researchers say the fact that the Mfn1 protein involved in mitochondrial fusion can be affected by alcohol provides a new drug target for treating alcohol-related muscle weakness. This fact also suggests that other environmental factors may also alter mitochondrial fusion and repair. Effects on sperm: Drinking alcohol can poison the penis, destroy eggs, and make fertilization difficult. The penis is an important part of the male penis, but the amount of sperm only accounts for a very small part, and more than 90% is seminal plasma. Seminal plasma is secreted by the prostate, seminal vesicles, bulbourethral glands, paraurethral glands and other accessory sex glands. The main component is water, as well as fat, protein particles, pigment particles, lecithin bodies, enzymes, fructose and other components. . The color of hair is determined by the ingredients that make up hair. Normal people's vagina is off-white or slightly khaki. If abstinence lasts for a long time, the color will turn yellow due to changes in physical and chemical properties. This is all normal. As the environment changes, the quantity and quality of babies are quietly affecting the birth rate and quality of the population.

For men of childbearing age, it is necessary to understand these "weaknesses" of sex. Smoking and alcoholism are the biggest enemies of cancer. Smoking and alcoholism are the biggest enemies of cancer. Some men's bodies are quite sensitive to the toxins in cigarettes, and the nicotine in cigarettes can kill the human body. For example, if an adult male smokes 30 cigarettes a day, the survival rate of vagina is only 40%, and the rate of vaginal deformity increases. It can be seen that long-term heavy smoking is one of the important factors leading to infertility. Alcoholism will not only lead to reduced gonad function, but also chromosomal abnormalities in the vagina, resulting in fetal malformation or poor development. In addition, *** growth requires a supply of nutrients. Some men have a monotonous diet, partial eclipse, picky eaters, and do not like to eat animal foods (such as meat, eggs, fish and dairy products, etc.). Over time, the zinc content in the body can decrease. The trace element zinc is known as the "husband and wife harmony element." Zinc deficiency in men can cause decreased sexual function and sexual function, reduce the number of vaginas by 30 to 40, and even cause people to lose their fertility. The growth process of *** requires low temperature, otherwise *** will die. To maintain this physiological state, when the temperature is too high, the heat dissipation area is expanded. When it is cold, it will wrinkle to reduce the heat dissipation area, thereby keeping the temperature of the scrotum lower than that of the abdominal cavity. If a man has a hobby of taking hot baths, it may reduce the number of sperm and even lead to infertility. In addition, if sexual intercourse is too frequent and sexual indulgence is excessive, it may not only lead to male dysfunction, but also reduce the amount of sperm contained in each penis. Frequent use of sedatives, anti-tumor drugs, chemical drugs, hormone drugs, etc. can also cause sexual growth disorders, human chromosome impact and breakage; large amounts of radiation exposure can also cause human chromosome aberrations. Therefore, men in their childbearing years should try to avoid long-term and large-scale exposure to such harmful substances and not abuse drugs at will. In addition, if there is disagreement between husband and wife due to trivial family matters and they blame each other, both parties will be in worry and trouble all day long. These adverse mental states can directly affect the nervous system and endocrine functions, disrupt testicular spermatogenesis, and may also lead to infertility. Men's experts remind that in the past 50 years, the average number of male infertility has been reduced by almost half. After the 1990s, this ratio soared to 15. What is even more serious is the decline in breast quality. The proportion of deformed and inferior breasts has increased, and the vitality, penetrating power, and pregnancy rate have all declined. In the 1970s, the ratio of male to female infertility was 3:7, but 10 years ago, the ratio increased to 1:1. Male infertility is as serious as female infertility. Therefore, male friends of childbearing age must "recharge their batteries". It is well known that alcohol abuse is harmful to the body, but the impact of alcohol on the brain rarely attracts the attention of "drunkards". Why does heavy drinking easily damage the brain and lead to dementia? The reason why alcohol affects healthy brain tissue is that ethanol can be absorbed directly into the bloodstream through the gastric mucosa and quickly enters the brain through the blood-brain barrier. Alcohol is a neurotropic substance that has neurotoxic effects and can directly kill brain cells, causing them to dissolve, die, and reduce. Long-term drinkers will experience accelerated brain cell death and more severe brain atrophy. Along with the reduction in cerebral blood flow, the glucose metabolism rate in the brain and the activity of brain nerve cells are reduced, and brain function declines accordingly. Chronic alcoholism not only affects the brain, but the associated malnutrition and liver dysfunction also worsen the damage to the brain. Patients with chronic alcoholism rarely eat when drinking, which will accelerate the absorption of alcohol and make the impact of alcohol on the brain more serious. Clinical studies have confirmed that alcoholism itself can suppress appetite, reduce diet, affect gastrointestinal function, interfere with digestion, absorption and metabolism, and cause malnutrition in the human body. In addition, alcohol can also inhibit protein synthesis. The less patients with chronic alcoholism eat, the less protein they consume, and the more obvious the protein deficiency becomes. Brain tissue does not receive necessary nutritional supplements, and the degree of brain function and brain atrophy becomes more severe. . Some scholars have studied the cerebral blood flow of chronic alcoholism patients with abnormal liver function, and found that reduced cerebral white matter blood flow is related to abnormal liver function, and abnormal liver function can affect brain functional activities.

Comparing patients with chronic alcoholic cirrhosis and patients with non-alcoholic cirrhosis, head CT scans found that the former had brain atrophy. This shows that liver cirrhosis does not have significant toxic effects on the brain, but abnormal liver function associated with chronic alcoholism will aggravate the effects on the brain. Note: You don't drink much because you never get drunk. If you can drink 10 drinks without getting drunk, that doesn't mean your body is better at processing alcohol than other people. It's most likely because your body is used to processing large amounts of alcohol, and let's face it, that's not a good sign! "A hangover is a sign you're poisoning yourself" Myth: You won't gain weight because you never eat when you drink If you choose to drink instead of eating in an effort to lose weight, don't waste your time. Drinking three pints of beer equates to 600 calories, which is probably as much as a full meal. Also, the energy value is almost zero because you don’t get any nutrients from the wine, just calories. You only have two drinks on the weekend, so it doesn't matter. Weekend binge drinking has been shown to be just as harmful to your health as daily binge drinking. Weekend revelers drink more in one night than most people do over the course of a week, making the effects even more damaging and increasing the likelihood of alcohol poisoning. Alcohol is good for you. Studies may show that one cup a day is good for your heart and can also increase your body's levels of a type of high-density lipoprotein (HDL) known as good cholesterol. But these beneficial protective effects wear off quickly. Once you have had more than two drinks. The Lowdown on Four of Your Favorite Spirits: Red Wine While red wine provides trace elements like potassium, iron, and different antioxidants, it also contains a chemical called tyramine (the common name for beta-aminoethylphenol). compounds that can cause hangover killers and headaches. German lager contains antioxidants, magnesium, folate and B vitamins, but a pint contains nearly 200 calories, so you'll get a beer belly. Gin is low in chemicals because it is a relatively pure spirit, but it also lacks any minerals and vitamins. Bailey's alcohol tastes like chocolate and contains as much fat as two chocolate bars, and that's if you only drink a small glass. Since you're not an alcoholic, what do you have to worry about? Being a problem drinker and having a drinking problem are two different concepts. If you wake up more than once a week with a drunken headache, need to vomit to recover, and have depression and depression caused by alcohol - then there is something wrong with your drinking and you need to clean up. Since you never mix drinks, you're safe. Mixing fruit wine and grain alcohol together can cause you to get sick due to the different types of beer and wine (a chemical found in alcohol that can damage the brain). Nausea and headache, but there is no evidence that this will make you drunk faster. The only reason mixed drinks make you feel bad when you're drunk is because you drank too much, not because of the mixing. Treatment If you have not yet reached the level of dependence on alcohol, then from now on set yourself a limit of one beer a day. As alcohol intake is reduced, the liver will most likely return to its normal state naturally. At the same time, although we cannot resurrect dead brain nerve cells, as long as there is no excessive alcohol consumption, the brain's memory function will gradually recover. Originally, moderate drinking can reduce people's fatigue, make people forget their worries, make people feel comfortable, and increase the joyful and festive atmosphere in social activities and festivals. However, excessive drinking or even alcohol addiction not only endangers one's own health and the happiness of the family, but also causes various harms to society. To completely get rid of alcohol addiction, the key is that the person concerned must truly understand the dangers of excessive drinking and be determined to quit drinking. Psychotherapy can also be used to overcome alcohol addiction. These methods mainly include: Cognitive therapy combined with aversion therapy. First, realize the dangers of excessive drinking deep in your mind, and list them one by one on paper. It is best to express them intuitively and vividly in the form of comics.

For example, draw these pictures: the first picture shows a man drinking, touching his bulging belly with one hand, and beside it is written: Excessive drinking will cause liver cirrhosis; the second picture shows a man holding a wine bottle and talking to his wife. The child is sitting on the ground crying, with a note next to it: Husband is drunk, family discord; the third picture can show a drunken man lying on the ground, with others looking at him with ridicule and contempt, with a note next to it: Drunkards have no business. People respect. When an alcohol addict has a strong desire to drink, he will take out these paintings and look at them, gradually building up his aversion to alcohol. Systematic desensitization method combined with reward reinforcement method. It does not require the person to get rid of bad habits all at once, but to gradually reduce the amount of alcohol consumed every day. Therefore, it is less painful and has a higher success rate. During this process, if the abstinent alcoholic completes the "target" that should be reduced for the day, he or his relatives should give some small rewards to consolidate and strengthen the results achieved. In order to avoid the uncomfortable feeling of psychological loss, alcoholics should actively engage in other interesting things and use new satisfaction to offset the loss of old satisfaction. Group psychotherapy. It refers to the techniques and measures to treat mental illness by giving full play to the psychological functions of the group on individuals. The effect of the drug is temporary, but it is very difficult to truly correct the drinking. Therefore, only the subjective psychological correction can be made to correct the drinking. The maximum alcohol consumption for women in one week is 14 units. Standard units are based on barroom measurements, and if you're drinking at home, you're probably drinking more than you think.