Those things about the magic medicine for losing weight

Those things about the magic medicine for losing weight

My parents met a stranger and asked the fat man who you were with a smile. During the Spring Festival, this limerick has a great potential in the circle of friends. You can watch a Spring Festival, but you can't describe the bitterness of long meat with "three pounds on holidays". No matter "shut up and stretch your legs", no matter how well you usually do it, it will all go up in smoke when it comes to holidays. So is there a magic medicine that can make people eat and drink without fear, and lose weight once they eat? Of course, there is such a magical medicine, but not in a drugstore, but in an advertisement.

Pick up the common diet pills on the market.

Sibutramine can reduce weight by suppressing appetite and decomposing fat. This medicine can not only make people want to eat, but also break down fat. It looks perfect, right? However, sibutramine has been found to cause serious cardiovascular risk, leading to stroke and heart attack. Therefore, on 20 10, the relevant departments of the European Union, the United States and China have suspended the sale and use of sibutramine. Since using sibutramine to lose weight involves great health risks, what about other magic drugs that claim to lose weight? Let's take a look at the common diet pills on the market.

L-carnitine

L-carnitine, also called L-carnitine, is a substance that the human body can synthesize by itself. In most cells of the human body, there is an organelle called mitochondria, which is where energy is generated.

If mitochondria are compared to engines and fat is compared to gasoline, the function of L-carnitine is to add gasoline to engines. Just like gasoline won't burn without driving, eating more L-carnitine without exercise won't consume fat.

From the point of view of evidence-based medicine, no research can prove that L-carnitine can lose weight, and the US FDA only approves it for L-carnitine deficiency.

In Europe and America, L-carnitine is mainly used as a nutritional supplement, that is, food. If you are healthy and can eat normally, there is no shortage of L-carnitine.

laxative

Laxatives are the most commonly used weight-loss drugs, mainly because they are relatively convenient to obtain and relatively low in price. When laxatives act on the human body, they will excrete the fat that should have been absorbed through the intestine, which is equivalent to reducing the "intake" of food in disguise.

In this way, laxatives seem to have a certain effect on weight loss. But look at the problem comprehensively. Laxatives not only excrete fat, but also amino acids, carbohydrates, vitamins and trace elements in food and probiotics in the intestine are very important substances to maintain health.

Taking laxatives for a long time will not only lead to the lack of vitamins and trace elements, but also lead to the disorder of intestinal flora, even damage the intestinal mucosa and destroy the intestinal immune function. Simply relying on laxatives, not dieting and not exercising, once you stop taking drugs, you will soon get fat again. Think of it this way: taking laxatives to lose weight is not worth the loss.

Dimethyl dipheptyl

At present, there are few studies on healthy obese patients taking metformin, and the evidence level of experimental design is not high. It seems inappropriate to call us healthy obese patients. We should call them ordinary obese people with no other diseases except obesity. German scholars 20 13 found that for ordinary obese people with body mass index greater than 27, they ate 2.5 tips every day for six months: maybe you are not fat at all.

Weight control has always been a compulsory course for beauty lovers. Medical evaluation of "fat and thin" has an index called body mass index, and the calculation is very simple.

Body mass index = weight (kg)+square of height (m2).

The body mass index of healthy adults in China is 18.5~24. Generally speaking, a body mass index greater than 24 is considered overweight, and a body mass index greater than 28 is considered obese.

Take beautiful women as an example. She is 1.65 meters tall and weighs 60 kilograms. After calculation, her body mass index is 22, which is within the normal range, so she is not fat. Taking Gramoxone and A at the same time can reduce the average weight by 6 kg, but the evidence level of this experimental design is low. Kashyap SR and others summarized the possible weight-loss mechanisms of dimethyl double dose, including central nervous system regulation, influencing obesity receptors, strengthening intestinal satiety signal and accelerating fat metabolism. At present, the FDA has not approved metformin for weight loss. Metformin has a strong gastrointestinal adverse reaction. Up to 53.2% people will have diarrhea and 25.5% people will feel sick.

However, in some specific groups, the weight-loss effect of Dimethyl Double Service is still worthy of recognition, including patients with type 2 diabetes, insulin resistance, obesity during pregnancy, polycystic ovary syndrome and so on.

Appendix:

There are safe and effective diet pills. At present, orlistat and Roslin are the first choice of internationally recognized weight loss drugs. Orlistat has a long-term record of safety and effectiveness, especially for patients with dyslipidemia and diabetes. Roxacillin is similar to orlistat, but the safety data of long-term use is limited. However, even orlistat, which has been recognized for its efficacy and safety and has been listed in China, will still produce gastrointestinal adverse reactions such as nausea, vomiting and fatty diarrhea during taking, which will bring inconvenience to daily life.

Diet pills are only suitable for obese people who still can't lose weight through diet control and exercise. Even the safest diet pills have adverse reactions, and the rebound problem can't be avoided after stopping taking them. It is difficult to lose weight easily without changing your living habits by taking diet pills, and there is no shortcut on the way to lose weight.