Is there any information that washing powder or other poisons enter the blood through the skin? thank you

After being stained with washing powder, your hands will feel greasy, which is difficult to remove by washing with water, and your skin will feel itchy and burning when it comes into contact with a high concentration of washing powder solution. I read a document that about 0.5% of the cleanser on the skin will penetrate into the blood. If there is a wound on the skin, the permeability will increase by more than 10 times. Chemical detergent toxins enter the human body, which will reduce the concentration of calcium ions in the blood, acidify the blood and make people easily tired. Because the harm of this kind of pollution is not obvious in a short time, it is often ignored. However, trace pollution continues to enter the body, and every little makes a mickle will have serious consequences, leading to various pathological changes in the human body. It seems that when washing clothes, people's hands should not directly touch washing powder. It is a good idea to wear a pair of rubber gloves.