What is the difference between atropine and epinephrine? Ask God for help

Atropine is a M-choline receptor blocker. The mechanism of action is to competitively antagonize the agonistic effect of acetylcholine or choline receptor agonists on M cholinergic receptors. The main pharmacological effects are: 1. Inhibiting gland secretion (mainly salivary glands and sweat glands) M3 receptors. 2. Dilate pupils, increase intraocular pressure, and regulate paralysis of eyeball muscles. 3. It has a relaxing effect on a variety of visceral smooth muscles. 4. Increase your heart rate. 5. Anti-vasodilator in small doses and dilation of blood vessels in large doses. 6. Mainly stimulating effect on the central nervous system. It is mainly used clinically for 1. colic caused by visceral smooth muscle spasm 2. Preoperative administration to inhibit intraoperative gland secretion in surgical patients. 3. Ophthalmology is often used for optometry and fundus examination. 4. Treat bradyarrhythmia caused by vagus nerve excitement. 5. Give large doses of medication to patients with septic shock to expand capillaries and improve microcirculation. 6. Used to antagonize organophosphorus pesticide poisoning. Epinephrine: Epinephrine is an adrenal alpha and beta receptor agonist. The main pharmacological effects are: 1. Excite myocardial β1 β2 receptors, increase myocardial excitability, and relax coronary blood vessels. 2. Acts on α receptors in vascular smooth muscles to constrict blood vessels in skin, mucous membranes and gastrointestinal tract, and acts on β2 receptors in blood vessels to constrict blood vessels in liver and skeletal muscles. 3. Blood pressure. The effect of epinephrine on blood pressure is mainly determined by receptors. When α and β receptors are stimulated at the same time, vasoconstriction and an increase in blood pressure occur. If an α-blocker is given first and then epinephrine is given, the main manifestation is a hypotensive effect. 4. Improve body metabolism, accelerate liver glycogen decomposition, and increase blood sugar. Main clinical applications: 1. Allergic diseases (1) Drug of choice for anaphylactic shock (2) Acute bronchial asthma attack (3) Angioneurotic edema 2. Cardiac arrest Stop: Epinephrine, atropine, and lidocaine are called Qianxin triple injections. 3. Treatment of glaucoma: Reduce intraocular pressure. To sum up, their differences are: 1. The receptors are different, one is the cholinergic M receptor. One is adrenal alpha and beta receptors. 2. The types of anti-shock are different, one is anti-septic shock and the other is anti-anaphylactic shock. 3. When using ophthalmic medications, one increases intraocular pressure and the other decreases intraocular pressure. 4. Atropine is the first choice for organophosphorus pesticide poisoning. 5. Atropine has an inhibitory effect on secretory glands, but epinephrine has no effect. 6. Adrenaline accelerates metabolism and increases blood sugar. 7. Atropine has an exciting effect on the central nervous system, but epinephrine has no effect on the central nervous system. Their main similarities are: 1. Both can relax vascular smooth muscles and regulate blood pressure. 2. Both have positive effects on the heart, speed up the heart rate, increase myocardial excitability, and increase cardiac output. 3. Have antispasmodic effects on smooth muscles and can be used for Visceral spasm are two completely different drugs with different action sites and mechanisms. The reason why they are compared is that they happen to be similar in some effects. But fundamentally, if you want to clearly understand the functions of these two drugs, I suggest you take a look at what cholinergic M receptors are and what cholinergic N receptors are. What are adrenal alpha receptors and what are adrenal beta receptors. What is the effect they have on the body after exciting them. What is their main distribution throughout the body? Because in clinical work, our choice of such neuroreceptor agonists is determined based on the symptoms we want to treat and the receptors at the site where they occur. It is not a matter of rote memorization of which medicine to treat which disease.