What is the cause of diabetes?

1, genetic factors: Diabetes has familial genetic susceptibility. However, this heredity still needs the role of external factors, mainly including obesity, reduced physical activity, unreasonable diet structure, virus infection and so on. 2. Obesity: Obesity is an important cause of diabetes. It is particularly easy to cause type 2 diabetes. Especially people with abdominal obesity. The main mechanism is that there is obvious hyperinsulinemia in obese people, which can reduce the affinity between insulin and its receptor, lead to the obstruction of insulin action and trigger insulin resistance. This requires islet β cells to secrete and release more insulin, which leads to hyperinsulinemia. This is a vicious circle of glucose metabolism disorder and β cell dysfunction, which eventually leads to serious β cell dysfunction and type 2 diabetes. 3. Insufficient activity: Physical activity can increase the sensitivity of tissues to insulin, reduce weight, improve metabolism, reduce insulin resistance, relieve hyperinsulinemia and reduce cardiovascular complications. Therefore, the reduction of physical activity has become an important factor in the pathogenesis of type 2 diabetes. 4, diet structure: high-fat diet can inhibit metabolic rate, make weight gain and obesity. Obesity leads to type 2 diabetes, and the incidence of diabetes in meat eaters is significantly higher than that in vegetarians. Mainly related to the high fat content in meat and the high calorie in protein. Therefore, the diet should be diversified, maintain a nutritional balance, and avoid overnutrition. 5. Psychoneurological factors: Psychoneurological factors play an important role in the occurrence and development of diabetes, and have been recognized by Chinese and foreign scholars in recent years. Because mental stress, emotional excitement and psychological pressure will cause a large increase in the secretion of some stress hormones, which are not only hormones that raise blood sugar, but also hormones that fight insulin. The long-term release of these hormones will inevitably lead to endocrine and metabolic regulation disorders, hyperglycemia and diabetes. 6. Virus infection: Some patients with type I diabetes get sick after suffering from colds, mumps and other viral infectious diseases.