What achievements has Japan made in medicine?

Judging from the winners of the Nobel Prize in Medicine over the years, many of them are scientists from Japan. This also directly reflects that Japan is really excellent in medical convenience. For example, Professor yoshinori ohsumi has made great achievements in studying autophagy, so he won the 20 16 Nobel Prize in Medicine. Japan's achievements in medical theory are advanced in medical equipment and scientific research. For example, the most advanced endoscopes, microscopes, CT and electronic endoscopes in the world are basically independently developed.