What are the precautions for ibuprofen sustained-release capsules?

Ibuprofen, the main component of ibuprofen sustained-release capsules, is an inhibitor of cyclooxygenase, which has considerable efficacy in relieving fever and pain. It can be used to relieve mild and moderate pain such as joint pain and dysmenorrhea, and has therapeutic effect on fever caused by common cold and influenza. However, it should be noted that patients with digestive tract ulcer should avoid taking it, and those with a history of bronchial asthma can cause bronchospasm; In addition, pregnant women and lactating women should use it with caution. Experts also reminded that excessive use of ibuprofen sustained-release capsules can cause headache, vomiting and drowsiness, but the symptoms can disappear by themselves after stopping the drug.

Usage and dosage of ibuprofen sustained-release capsules: oral. Adults, 1 capsule once, twice a day (once in the morning and once in the evening), or as directed by the doctor. Ibuprofen sustained-release capsules can inhibit the synthesis of prostaglandin and have analgesic, antipyretic and anti-inflammatory effects. And is a sustained-release dosage form, so that the drug is gradually released in the body. It can relieve pain for 12 hours every time, and it is recommended not to use it repeatedly within 12 hours. If there are special circumstances, it should be taken under the guidance of a doctor.

If ibuprofen sustained-release capsules are used with other drugs, drug interactions may occur, so attention must be paid to:

1. When this product is combined with other antipyretic, analgesic and anti-inflammatory drugs, it can increase gastrointestinal adverse reactions and may lead to ulcers.

2. When this product is combined with anticoagulant such as heparin and dicoumarin, it can prolong prothrombin time and increase bleeding tendency.

3. When the drug is combined with digoxin, methotrexate and oral hypoglycemic agents, it can increase the blood concentration of these drugs, so it is not suitable for combination.

4. When the drug is used with furosemide (furosemide), the sodium excretion and hypotensive effect of the latter is weakened; When combined with antihypertensive drugs, it also reduces the antihypertensive effect of the latter.

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