Reflections on "Working Cell"

"Working Cell" was originally born in teacher Shimizu's essay manuscript.

The reason is that my sister thinks senior high school biology is too obscure (in fact, I think it's okay, they are all people who have experienced nine-year compulsory education and don't talk much), so please ask teacher Shimizu, "If you can draw these cartoons to teach me, it will be much easier to understand."

Miss Shimizu: Well, I think so. (Start liver draft)

So working cells were born because of such an idea.

First of all, the style and production of this cartoon are excellent. After the animation, the drawing of scenes and characters has maintained a high level that is not lost to the original comics. Color animation works also have a good grasp of tone allocation and quality. The author has also made a lot of efforts in personnel design. The main working cells are anthropomorphic, and at the same time, the functions of the cells themselves are combined with images and settings, such as the migration and phagocytosis of white blood cells. A child can shoot antibodies indefinitely with a spray gun because of the small image of platelets and the ability of B cells to produce antibodies. This animation is a successful work for all ages, and it has become a comic drama in 20 18.

At the same time, the work unit is good at making popular science knowledge interesting and easy to understand with personification and scene transformation. For example, the introduction of neutrophil family has expanded my understanding of cell morphology: monocytes are still immature cells after entering blood vessels, but they also have the strongest phagocytic ability among neutrophils, and will deform into macrophages after leaving blood vessels; Basophils stay in the blood for a short time, and the granules of cells contain histamine, heparin and allergic slow-reaction substances, which become mast cells after entering connective tissue and mucosal epithelium. At the same time, I also learned some relatively unpopular knowledge. For example, although eosinophils have weak phagocytic ability to bacteria and pathogens, they have strong phagocytic ability to antigen-antibody complexes, which can effectively fight parasites in parasites. Dopamine particles attached to the surface of NK cells can activate the killing activity of LAK- 1 molecule on its surface, thus effectively attacking cancer cells, malignant tumors and viruses. T cells, helper t cells, etc. It needs to be cultivated and trained in the thymus to have the ability to be a weapon of the immune system. Their predecessor is pluripotent stem cells and so on.

Finally, I think this animation has profound humanistic significance. The initial T cells that have never been activated can't attack and devour bacteria and infected somatic cells, feel desperate and powerless to themselves, and show their understanding of human self-identity. Eosinophils were criticized by other cells because of their weak phagocytosis, and finally showed their talents in fighting gastric parasites, reflecting their persistence in self-worth. Black T cells and neutrophil families are responsible for defending members of the body, such as red blood cells and somatic cells, but they don't understand each other, even alienate and misunderstand each other, pointing out the communication problems between different groups in human society today. Cancer cells were born in the period of somatic cell division, and there are replication errors. As soon as he got his life, he was immediately hunted down by other immune cells, survived after seeing his partner killed with his own eyes, and then infected the tissues in his body through crazy proliferation in an attempt to violently surround the unsuspecting immune cells and make them die. As a living individual, cancer cells show a strong desire to live, hoping that they can live like normal cells and not be hated, but the existence of cancer cells is a great harm to the human body itself. White blood cells said to him when cancer cells were seriously injured: "I think you are also a cell." The same is true of human society. The emergence and existence of different kinds is pitiful, but it is also hateful. Just like killing or isolating a patient infected with an incurable infectious disease and leaving him to fend for himself, in order to save the lives and interests of most people, heretics are often deprived of their right to exist. In the end, when the owner of the body is in danger, the cell desperately takes all measures to save the body. Although most working cells will die in this disaster, in order to preserve the world that once existed, working cells persist in working until the last moment.

Bacterial invasion will lead to hemolysis of a large number of red blood cells, cold will lead to infection of a large number of somatic cells and become the target of immune cells, parasitic infection will lead to apocalypse animals in the body, pollen allergy will lead to histamine flooding in the body, heatstroke will lead to the end of drought in the world of cells, an intake of antibiotics can launch an indiscriminate attack on cells and viruses, and a scratch will open a bottomless pit in the body and cause a large number of bacterial invasion. In the face of such an uneasy day, cells are still trying to live strong for you and rely on their own strength to solve heavy and dangerous challenges for them. What we can do is to cherish our health, not only for ourselves, but also for the 37.2 trillion cells in your body that live very hard.