What are the benefits of umbilical cord blood? Who wants to talk about it?

Umbilical cord blood is the blood left in placenta and umbilical cord after fetal delivery, umbilical cord ligation and disconnection, and is usually discarded. In recent ten years, it has been found that umbilical cord blood contains hematopoietic stem cells that can rebuild human hematopoietic and immune systems, and can be used for hematopoietic stem cell transplantation to treat more than 80 diseases. Therefore, umbilical cord blood has become an important source of hematopoietic stem cells, especially unrelated hematopoietic stem cells. It is also a very important human biological resource.

function

Umbilical cord blood contains a lot of stem cells, which are the seeds of life. They will differentiate into various cells of the human body and bear various fruits-blood cells, nerve cells, bone cells and so on. With the development of science and technology, medical experts have developed a method to treat diseases by using stem cells from umbilical cord blood.

Stem cells are cell groups with self-renewal, high proliferation and multi-directional differentiation potential. These cells can maintain the characteristics and quantity of their own cells through division, and can further differentiate into various tissue cells, thus playing an active role in tissue repair.

Medical research in recent 30 years has found that umbilical cord blood is rich in hematopoietic stem cells (HSC), which can rebuild human hematopoietic and immune system, and can be used for hematopoietic stem cell transplantation to treat blood system, immune system, genetic metabolism and congenital diseases. Therefore, umbilical cord blood has become an important source of hematopoietic stem cells, widely used in clinic and a valuable human biological resource.

Storage meaning

Cure a disease

Worldwide, umbilical cord blood has been used to treat various types of leukemia, aplastic anemia, lymphoma, multiple myeloma, neuroblastoma, mucopolysaccharidosis, thalassemia, myelodysplastic syndrome, primary immunodeficiency disease, chronic granuloma and other more than 80 diseases.

According to the "Management Standard of Umbilical Cord Blood Hematopoietic Stem Cell Therapy Technology (Trial)" issued by the Ministry of Health of China, the indications of umbilical cord blood hematopoietic stem cell therapy technology include the following 10 categories:

By the end of 20 13, the number of cases of umbilical cord blood transplantation in China has exceeded 1000, and the number of cases of umbilical cord blood transplantation has increased year by year, about 150 cases per year. However, compared with the leading regions in the world, umbilical cord blood transplantation in China is in its infancy. With the increase of cord blood storage and the maturity of transplantation technology, cord blood transplantation in China will gradually approach the international level.

Cord blood bank provides cord blood for treating 37 diseases such as leukemia, lymphoma, aplastic anemia, hemophagocytic syndrome, chronic granuloma, Gaucher's disease and neuroblastoma.

Treatment prospect

clinical trial

2 1 century is the century of biology, and cell therapy, as a biological therapy method, has opened up a brand-new idea for the treatment of human diseases. By the end of May 20 14, 928 clinical studies related to umbilical cord blood had been registered with the National Institutes of Health (NIH).

Autoimmune diseases:

Sun god

lupus erythematosus

multiple sclerosis

Cardiovascular and cerebrovascular diseases:

Congenital heart disease

Heart repair and recovery

Ischemic attack

Nervous system diseases:

cerebral palsy

Hypoxic ischemic encephalopathy

autism

Traumatic brain injury

spinal cord injury

hearing loss

Amyotrophic lateral sclerosis (spinal cord)

Alzheimer's disease (Alzheimer's disease)

Malignant diseases:

mastocarcinoma

renal carcinoma

Congenital diseases:

Duchenne muscular dystrophy

Baker's muscular dystrophy

cystic fibrosis

Other diseases:

1 type diabetes mellitus

AIDS

Cartilage repair

Severe limb ischemia

One person saves, and the whole family benefits.

The utilization rate of umbilical cord blood of relatives at home is 25%-50%, which increases the chance of finding a donor in their own home.

Acquisition method

Umbilical cord blood collection is different from traditional bone marrow collection. It does not need anesthesia, is painless and has no side effects. Therefore, it has no adverse effects on mother and baby, and belongs to "waste utilization, turning waste into treasure".

The collection needs to be completed by professional qualified medical personnel. After the baby is born, collect umbilical cord blood with a sealed blood bag filled with anticoagulant.

The collector must be a doctor or nurse with professional qualifications and trained in cord blood collection.

Storage step

1. Before delivery, pregnant women should contact the local umbilical cord blood preservation institution.

2. Sign the Letter of Intent for Donating Umbilical Cord Blood Hematopoietic Stem Cells/Umbilical Cord Blood Hematopoietic Stem Cells Storage Agreement, and receive the umbilical cord blood collection instrument.

3. When pregnant women give birth, umbilical cord blood is collected by medical staff.

4. The pregnant woman calls the cord blood bank immediately after delivery, and the successfully collected cord blood will be transported to the cord blood bank within 24 hours by a professional blood collector driving a special blood collection vehicle.

Umbilical cord blood bank uses the most advanced equipment to prepare and test umbilical cord blood.

6. The umbilical cord blood that passed the test was finally stored in a liquid nitrogen tank at-196℃ to ensure the activity of umbilical cord blood.

7. The customer will receive the "cord blood test report" within 60 working days after the baby is born.