Antibodies produced by cell clones formed by the fusion of mouse myeloma cells and a B cell are called

the answer is a, there should be no doubt about it.

There should be a detailed introduction to monoclonal antibodies in the textbook. Let me talk about options B, C and D..

Polyclonal antibody: natural antigen molecules usually contain multiple different epitopes, so after the antigen stimulates the body, multiple B cell clones are activated, and the resulting antibody actually contains immunoglobulin for each epitope of the antigen, which is called polyclonal antibody. The ways to obtain polyclonal antibodies are: animal immune serum, convalescent patient serum or vaccinated people.

Single-chain antibody: Single-chain antibody is a synthetic antibody expressed in E.coli by genetic engineering technology. It has only one chain of complete antibody, so it is named as single-chain antibody. It is composed of antibody heavy chain variable region and light chain variable region connected by short peptide of 15 ~ 2 amino acids.

chimeric antibody: Take human-mouse chimeric antibody as an example. It is an antibody prepared by genetic engineering technology. The V-region gene of mouse-derived antibody and the C-region gene of human antibody are spliced into a chimeric gene, and then inserted into a vector to transfect antibody molecules expressed in myeloma tissues.