When do dogs get vaccinated and why do they get sick after vaccination?

Dogs should be vaccinated when they are healthy, because the immunity of dogs is very low 7- 10 days after vaccination.

When the dog is sick, wait until the dog is fully recovered. The vaccine can be given without the number of days, but it can be delayed for a few days. Dogs can be given when they are cured, usually when they are puppies.

Canine vaccine is a good way to prevent canine infectious diseases. It has been proved that in most cases, vaccines have a strong protective effect on dogs, and many dogs have avoided getting sick because of vaccination. However, some parents have a fever and a cold after taking their dogs for vaccination. What is the reason?

Canine vaccine is a good way to prevent canine infectious diseases. It has been proved that in most cases, vaccines have a strong protective effect on dogs, and many dogs have avoided getting sick because of vaccination. However, the protection rate of vaccine is not 100%, and it should be 90% ~ 95% in theory. Some parents have a fever and a cold after taking their dogs for vaccination. What is the reason? So, let's talk about what factors may affect the effectiveness of the vaccine.

1. When should dogs be vaccinated?

(1) specific immunization program

Generally speaking, dogs are vaccinated in the 7-8 weeks after birth. If they miss the time, they can also be vaccinated.

Multiple injections of the first needle: two doses of the first needle are injected from the 7 th to 8 th week after birth, and four doses of the first needle are paid attention to for dogs over two months old.

Second needle reuse: inject the second needle quadruple after the first needle interval 15 days.

Multiple injections of the third needle: 6 injections of the third needle every second needle 15 days.

The fourth injection: the fourth injection of rabies vaccine one week after the third injection.

(2) Dogs over 2 months old are vaccinated.

If it takes 60 days for dogs to start vaccination, they can directly inject 2 doses of quadruple+1 six-needle+1 needle rabies vaccine. The inoculation interval is the same as the first time.

(3) Vaccination of adult dogs.

1 year later, you need to give dogs a shot for six couples and rabies a shot every year. The injection time is counted from one year after the injection last year. 1 week later, dogs should be injected with six pairs first.

It is worth noting that the time for dogs to be vaccinated is mandatory. Generally, the interval of inoculation is 15 days. If you forget to inject, you can postpone the vaccination for up to one day, otherwise the previously injected vaccine is likely to fail.

Second, why do dogs get sick after vaccination?

1. Dogs produced insufficient antibodies after vaccination.

Whether the vaccine can prevent diseases depends on whether the vaccine can stimulate dogs to produce antibodies and the number of antibodies. It is generally believed that infectious diseases can only be prevented if the serum antibody is greater than 10 international unit per milliliter. About 30% of dogs showed antibodies after inoculation 1 month, and the antibody reached the highest level after complete inoculation 1 month. In other words, it does not mean that dogs are immune to the diseases targeted by the vaccine immediately after vaccination. According to the research, the level of antibody produced by dogs to vaccine can be divided into four groups: non-response group, accounting for about 5% of the injection times, mostly due to genetic reasons; Low reaction group. It accounts for about 10% of the injection, which is related to heredity, age, obesity, immunity and other factors, and it is in a moderate reaction group. About 65% injection, high reaction group. About 20% of the injections. Dogs in non-response group and low response group may still get infectious diseases after vaccination.

The dog was infected with the virus before vaccination.

Even if the dog is examined before vaccination, all the indicators are normal, and it may still be undetectable because it is in the incubation period. Antibodies produced by vaccines are only effective against viruses in blood, but not against viruses entering cells. Therefore, if you are infected with the virus before vaccination, vaccination is ineffective.

3. Improper storage or use of vaccine will lead to vaccine failure.

Vaccines are not suitable for freezing, which will destroy the molecular structure of vaccines. If stored at about 37℃, it should not exceed 1 month, and if stored at about 4℃, it should not exceed 1 year. If the storage time is too long, the immune effect will be reduced. If you keep it at home, you can keep it in the freezer of your home refrigerator. In addition, the vaccine injection is more effective in the dog's neck and not suitable for injection in the dog's buttocks. There is more fat in buttocks, but less immunocompetent cells. The antibody concentration produced after injection is low, and the antibody drops rapidly.

4. When the dog is in poor health, some drugs are being used.

When the dog is in poor health, such as parasites, high fever, and being treated with drugs, vaccination will cause immune failure. Therefore, it is necessary to immunize dogs under the premise of health in order to improve the chances of successful immunization. However, don't think that everything will be fine after vaccination. It is best to do a full set of tests after vaccination. In addition, the virus will mutate, and even if it is vaccinated against diseases caused by the mutated virus, it will have no effect. Pay attention to the continuity of vaccination, and the time interval should not exceed one year. It is best to vaccinate the next vaccine one or two months in advance. Because the immunity after vaccination will gradually weaken over time, and in the end, the immunity is already very weak.

6. Dogs under stress are likely to lead to vaccine failure.

Because pets have weak immunity in emergency, animals are not suitable for vaccination under stress. The change of living environment or food is a kind of pressure for puppies. Therefore, we will encourage dogs to get vaccinated after getting familiar with the new environment for half a month.

7. Dogs lack certain vitamins, which affects the immune synthesis of the body.

Antibody is an immunogenic globulin. When the body is malnourished, such as vitamin A or E deficiency, it will also inhibit the normal protein synthesis of the body, thus reducing the immune response.