Why do some people succeed in IVF the first time? Is there any secret to success?

The success of in vitro fertilization is affected by many factors. A friend of mine failed three times because his health was so bad that he could not survive within three months each time.

What factors affect the success of in vitro fertilization?

1. The age of the woman is the main factor in the success of IVF.

Since the quality of eggs will gradually deteriorate with age, the success rate of IVF is highest among those aged 25-35 years old.

>The success rate and live birth rate of IVF at the age of 40 years old greatly reduced.

2. The influence of various infertility factors

The woman’s severe endometriosis and polycystic ovaries will affect the success of IVF.

Severe oligospermia and azoospermia on the part of the man, or excessive sperm abnormalities will also affect the success rate of IVF.

3. The condition of the woman’s uterus

Whether the endometrium is healthy is the most important factor affecting embryo implantation.

Endometrial damage, adenomyosis, endometritis, endometrial polyps or other lesions of the endometrium may affect embryo implantation, and endometrium that is too thin or too thick will not affect embryo implantation. Suitable for transplantation!

Before in vitro fertilization, it is necessary to check the condition of the uterus and adjust the uterine environment.

4. Are the DNA chromosomes abnormal?

For patients with DNA chromosomal abnormalities, even if the embryos are successfully cultivated, the failure rate and miscarriage rate are higher.

5. Are excellent embryos produced?

Excellent embryos are the main prerequisite for successful IVF. The six-level grading method of embryos: novel embryos of levels I to IV can be used for test tube transplantation, and levels I and II are excellent embryos.

6. Strengthen exercise and enhance physical fitness.

Not only is it beneficial to improving the quality of sperm and eggs, it is also beneficial to the survival rate of excellent embryos and improving the success rate of test tubes!

7. Mentality is very important!

Maintain a positive and optimistic attitude, believe that the baby will come, and do not be overly anxious. Bad mood has a great impact on the successful implantation and development of the embryo!

It is impossible to say whether or when in vitro fertilization will be successful. This is related to many factors, such as mothers’ own physical constitution, age, cause of disease, etc., as well as differences in medical technology. Therefore, the price of successful IVF for two different mothers may be very different.

Generally, a successful test-tube baby costs about 15,000 yuan at one time. If the condition is complex and requires three or four test-tube babies, the cost may be tens of thousands.

Sometimes IVF is like winning the lottery. Some people fail seven or eight times, while some people succeed once. Of course, during the test tube process, doctors will definitely choose the best quality embryos for implantation.

As for mothers’ poor physical condition before IVF, doctors will also help mothers adjust their bodies to the best condition for conception. At the same time, doctors will clearly inform you of some of the pros and cons during the conditioning process. Relax your mind, and being too nervous will also affect the implantation of the embryo on the endometrium.

After the test tube is completed, you need to lie down and rest for a period of time, but the length of time varies from person to person. Some women have to lie down for more than half a month after IVF, and some only need to lie down for two or three days. Try not to do physical work at ordinary times, and keeping your mood comfortable is the best state.

In addition to chance, the most important factors for the success of IVF are of course the mother's physical condition and the condition of her husband's sperm.

Let’s talk about the man’s semen first. If the husband is older, has bad habits of smoking and drinking, is obese and does not like to exercise, and has poor sperm motility, even if he chooses higher-quality sperm, the quality of the final fertilized egg may still be It is poor and cannot survive in the female body.

As for the woman’s situation, it’s more complicated.

1. Endometrial conditions

If you have experienced intrauterine adhesions during induced abortion or dilation and curettage surgery for other reasons, resulting in damage to the endometrium;

If there is endometrial hypoplasia and the endometrium is thin;

Both of the above may lead to poor endometrial receptivity, and the fertilized egg cannot implant and grow in the endometrium. In vitro fertilization fail.

Therefore, once endometrial lesions are found, IVF should be performed after gynecological clinical treatment improves, which can improve the success rate.

2. Uterine body conditions

If there is adenomyosis, uterine fibroids, adenomyoma;

If there is a septate uterus, unicornuate uterus , bicornuate uterus and other congenital uterine developmental abnormalities.

The above two conditions may lead to abnormal uterine anatomy and affect the further growth of fertilized eggs.

Therefore, once serious adenomyosis and other lesions are found, drug or surgical treatment should be used to improve the condition before in vitro fertilization is performed. if. If a septate uterus has congenital abnormal uterine development, uterine repair and plastic surgery can be performed before transplantation if necessary.

3. Endocrine conditions

If a woman has luteal insufficiency, hyperprolactinemia and other female hormone abnormalities, the risk of miscarriage will easily increase after pregnancy.

The presence of metabolic diseases such as insulin resistance and diabetes will also increase the risk of miscarriage.

Therefore, if hyperprolactinemia is found before pregnancy, drugs should be used to normalize the condition before in vitro fertilization; if metabolic syndrome exists, the metabolic syndrome should be improved before conception can occur.

4. Psychological factors

The process of pregnancy is very complicated, and psychological factors also have an important impact. Women experience more social pressure than men regarding infertility. Haste makes waste, and anxiety is also detrimental to pregnancy. Know how to properly relieve stress and regulate emotions.

It is not easy to get pregnant, so I cherish it very much. I hope that all mothers who undergo in vitro fertilization can have healthy children. If there are underlying diseases, be sure to go to the corresponding department for treatment and get better before proceeding with IVF. Don’t just be quick and urgent.

Hello, I am glad to have the opportunity to answer your questions and hope that our answers will be helpful to you.

First of all, there are many factors that will affect IVF. The details vary from person to person. Some people may be able to succeed in one go, while others may have to go through a long process. Of course, the specific influencing factors It can be summarized as follows:

First, the age of a woman

Generally speaking, the older the age, the lower the probability of fertilization. Among them, women aged 25-35 years old The probability is relatively high at that time, but if you are over 35 years old, your ovarian function and egg quality will significantly decline. At this time, the success probability of IVF will significantly decrease.

Second, the difference in ovarian reserve function

Ovarian reserve function refers to the number of primordial follicles contained in the ovarian cortex. It represents the level of female egg quality and quantity. , so this is also very important.

Third, the causes of infertility are different

This depends on what causes your infertility, such as oligoasthenozoospermia, azoospermia or Those with a large number of deformed sperm are more serious, so the success rate is lower. However, if there is no big abnormality, just advanced age or other factors, then it is easier to succeed.

Third, immune factors

Abnormally increased activity of systemic or local natural killer cells may have a toxic effect on the embryo and is not conducive to implantation, so the success is relatively low. Strangely, the better immunity you usually have, this time it becomes a disadvantage.

Fourth, the mental aspect

Those who are good at relieving stress, or who are relatively relaxed from psychological pressure, are often more likely to succeed in IVF, but if they are more anxious, or often stay up late and work overtime, Then it will be more difficult.

“Why have I failed many times of in vitro fertilization? Others can succeed in one attempt”, “Why didn’t I react after taking the ovulation injection?”, “What is the reason? Others can succeed.” I can’t succeed,” and other questioning words.

At present, IVF is a very important way to treat infertility, and there are many people in demand. Although the success rate is gradually increasing every year, some people still fail repeatedly, and some people succeed once. What is this? Why? What reasons can lead to test tube failure?

Causes of test tube failure:

1. Failure to respond to ovulation-stimulating drugs, or the response is so poor that the ovaries cannot Produce a sufficient number of mature eggs

2. Special reasons for the patient's pelvic anatomy make egg retrieval difficult or even impossible

3. 20% of the eggs are lost due to their own reasons or sperm. Too few and too weak to fertilize

4. 20% of fertilized eggs cannot develop normally or undergo degenerative changes, so that they cannot be implanted back into the uterine cavity

5. Although the embryos are Implanted into the uterine cavity, but unable to implant or become pregnant, this situation accounts for 80%

In addition, in terms of female egg abnormalities, as women age, the number and quality of eggs will begin to decline, especially The decline is extremely obvious after the age of 35. The pregnancy rate of 40-year-old women drops to less than 10%, and the possible pregnancy rate of 45-year-olds is less than 5%. The best childbearing age is between 23-35 years old. The decrease in egg number and overall quality is one of the main reasons for test tube failure.

Furthermore, the fertilized egg fails. After the egg is removed, the egg must be combined with the male's sperm to form a fertilized egg. The failure of this link is related to the quality of eggs and sperm, which is not easy to predict in advance.

Generally, couples who fail at this step often cannot find the specific cause of infertility after many years of investigation and many projects. This shows that the reason why they cannot get pregnant is probably because of poor egg or sperm quality. The proportion of this happening is about 3%. The quality of the eggs has a greater impact on this link, but the sperm also plays a certain role.

Failure to form an embryo depends on the quality of the fertilized egg. If the fertilized egg is not good, or the quality of the embryo formed is not good, it will lead to failure and the transplant cannot be performed.

When the transplantable embryo is transplanted into the mother and she waits for the mother to conceive, the failure rate at this stage is relatively high, which is more obvious for older women, especially women after 40 years old.

There is no secret to this, it is just gambling. Betting on luck and blocking the probability. If you lose the bet, you will fail! Many people I know are successful in transplanting one follicle and one embryo at a time. The probability for everyone is incalculable

My best friend Dabao and Xiaobao all succeeded in one go. Tell us your feelings 1. Choose the right hospital. There is a difference between a hospital doctor treating 10,000 patients a year and a doctor treating 1,000 patients a year. Moreover, the technology and vision of large hospitals keep up with the world’s standards.

2. Choose the right doctor. Choosing the right doctor means the plan is appropriate. Suitable eggs can be retrieved. Young chief physicians and deputy chief physicians with Ph.D.s in good hospitals are the first choice.

3. The mentality must be right. This requires the attitude of treating a dead horse as a living horse, and the success rate will be high.

The ancients said. There are three kinds of unfilial piety, the greatest of which is to have no descendants. Although people’s concepts today are very different from those of the ancients. There are also many people from the Ding He family. However, due to various reasons, many people who want to have children are unable to conceive. Nowadays, with the development of social science and technology, in vitro fertilization is also a method.

IVF is divided into several processes: ovulation induction treatment. Egg retrieval, in vitro fertilization, embryo transfer, luteal support, pregnancy confirmation.

During these processes. Among them, ovulation induction treatment is the most critical. Because not every egg can be fertilized. Not every fertilized egg develops into a viable embryo. Therefore, multiple eggs need to be retrieved from the mother to ensure that the embryos can be successfully transferred.

You should also pay more attention to nutrition after IVF transplantation. Drink more water. On the first day after that, I mainly eat liquid food. There are many staple foods, mainly foods that are easy to digest. Don't eat spicy, cold, etc., eat more fruits. to ensure nutritional supply.

After IVF embryo transfer. Expectant mothers don’t have to worry too much. Keep a normal mood and a happy mood. for the child's development. Also a great support.

Under normal circumstances, the monthly chance of natural pregnancy for a normal couple of childbearing age is no more than 20%. In other words, not every couple who wants a baby can get one every month. Likewise, IVF is not successful in every cycle.

At present, the success rate of reproductive centers with mature and standardized technology in our country is generally around 50%. However, this is only big data in the general environment and does not represent the success rate of an individual. It depends on the individual's age, uterine and ovarian function and other specific conditions. It all depends on the situation. Everyone is different. Some people are slightly older, but in good physical condition, and may succeed in one visit; while some people, although older in age, have health problems of one kind or another, and may succeed twice or twice. It only takes three times to succeed, so there is no way to generalize about this. The specific situation requires the doctor to see your examination report, and analyze and recommend what to do for you based on your actual situation!

As the pressure in today’s society becomes more and more intense, there are more and more infertile people. In order to be able to conceive a baby of their own, many people have suffered a lot. Of course, IVF also gives them one more choice. Although IVF is relatively mature now, it cannot guarantee 100% success.

So what factors affect the success rate of IVF?

1. Age

The woman’s age is a key factor affecting the success of IVF. Women aged between 25-35 have the highest success rate, and those over thirty-five will have the highest success rate. The success rate is greatly reduced. The older you are, the lower the success rate is of course.

2. Endometrial environment

The uterus is where the baby will stay for ten months. If the endometrium is damaged or there is uterine disease, this may cause the embryo to fail. Implantation will affect the success rate. Test tubes also have very high requirements for the endometrium. If it is too thick or too thin, it will make it difficult for the embryo to implant. Therefore, before many people undergo transplantation, doctors will ask the patient to undergo hysteroscopy and then transplant.

3. Embryo quality

Although the quality of embryos is said to be better the younger they are, there are also many young people whose embryos are not of good quality. When the embryos are not good, they will not be fertilized. Therefore, high-quality embryos are an important condition for success.

4. Chromosomes

Some couples have chromosomal abnormalities. Although these couples can conceive through in vitro fertilization, the failure rate and miscarriage rate are very high.

5. Mental state

Psychological state is extremely critical to the success rate of IVF. Many people will inevitably be very nervous about IVF, both psychologically and financially. But being too nervous will make it easier. Endocrine disorders make it difficult for the embryo to implant. IVF is a long journey. Since you choose to go, you must maintain an optimistic attitude, so as to increase the success rate.

Here I wish all the sisters who choose and prepare for in vitro fertilization a success!