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The best way to lose weight
At present, scientific methods to lose weight mainly include: strengthening lifestyle intervention, application of diet pills, metabolic surgery and endoscopic intervention. Everyone needs to choose a suitable scheme according to the comprehensive evaluation.
Lifestyle intervention to lose weight-effective but slow and difficult to adhere to.
Based on a variety of research results and clinical experience, lifestyle intervention is the first-line treatment for weight loss and weight control, that is, adjusting diet structure, reducing calorie intake and increasing physical exercise, improving lipid metabolism disorder and reducing visceral lipid deposition. But in fact, influenced by various factors in life, not many people in the real world can completely change their lifestyle and insist on losing weight [1].
Lifestyle weight loss is to reduce energy intake and increase exercise. If you can persist for a long time, the weight loss effect is obvious and safe. But in fact, influenced by various factors in life, it is often difficult to persist for a long time, and giving up halfway leads to repeated weight. In order to take lifestyle intervention to lose weight, we must find a sustainable lifestyle.
Drug weight loss-effective but side effects can not be ignored
There are three main mechanisms of action of diet pills: acting on the center to suppress appetite, increase satiety, reduce intestinal nutrient absorption and increase energy consumption. The effect of diet pills is very obvious, but the use of diet pills is difficult and tortuous. At present, only orlistat listed in 1998 and two drugs listed in 20 12: phenamine and roxacillin continue to be used [2].
In addition to the above-mentioned drugs that can be used to lose weight, drugs used to treat diabetes, such as biguanides and GLP- 1 receptor agonists, have been proved to have the effect of controlling weight [3]. Although the drug has obvious weight loss effect, its adverse reactions can not be ignored, such as diarrhea, loss of appetite, renal failure and even depression and suicidal tendency, which need to be taken under the guidance of a specialist.
Metabolic surgery to lose weight-effective but irreversible damage to organs
In recent years, metabolic surgery has attracted great attention in the medical field. At present, the widely accepted metabolic surgery methods for weight loss include laparoscopic gastric sleeve resection, biliary-pancreatic bypass duodenal transposition and laparoscopic gastric bypass, among which gastric bypass is particularly effective. The data show that obese patients who underwent metabolic surgery not only lost weight obviously, but also improved their abnormal glucose and lipid metabolism after surgery [4].
Although the effect of metabolic surgery on weight loss is obvious, we should still face up to its shortcomings, such as permanently and irreversibly changing the structure of digestive tract, the large gastric sac with distal opening can not be used for gastroscopy, dumping syndrome, hypoglycemia, anastomotic ulcer and so on will occur for a long time, and the incidence of vitamin deficiency and anemia is high.
In addition, metabolic surgery for obesity requires certain indications, and not all obese people can choose metabolic surgery for treatment.
Endoscopic interventional therapy for weight loss-effective but not yet fully developed
With the continuous development of endoscopic medicine, endoscopic intervention weight loss technology gradually appeared. This kind of technology is suitable for obese people with lifestyle changes, poor drug treatment effect and unable to accept or tolerate metabolic surgery.
Endoscopic gastric bypass stent system implantation is a new interventional weight loss technique. A cannula was placed in duodenum and upper jejunum through painless gastroscope to isolate chyme. After implantation, chyme from the stomach passes through the lumen of the cannula, and bile and pancreatic juice are isolated outside the cannula, so that bile and pancreatic juice "shunt" and meet food at the distal end, reducing the digestion and absorption of sugar and fat, thus achieving the effect of losing weight without changing the physiological and anatomical structure of the patient.
Finally, I need a friendly reminder that losing weight is for health, and we can't put the cart before the horse and sacrifice health to maintain the figures on the weighing scale. It is not difficult to lose weight. After comprehensive evaluation of their own conditions, try to refer to the above scientific weight loss programs. If in doubt, you can go to a professional hospital to find a nutrition department or a weight loss clinic for consultation ~
References:
[1] Effect of lifestyle intervention on blood lipid in obese patients with stroke [D]. Hebei Normal University, 20 18.
[2] Liu Yingmin. Obesity, type 2 diabetes and Sanico [J]. Liaoning Journal of Practical Diabetes, 2001:13-14+36+57.
[3] Zhu Huijuan, Jin. The present situation and progress of diet pills [J]. Journal of China Academy of Medical Sciences, 2011:31-35.
Diabetes Branch of Chinese Medical Association, China guidelines for prevention and treatment of type 2 diabetes (2020 edition) [J]. China Journal of Diabetes, 202 1, 13(4).
[5] OBES SURG, 1995,5:3 14; Yang, Xu Hong, et al. Clinical study of insulin resistance in patients with type 2 diabetes after gastric bypass [J]. Armed Police Medicine, 2007, 18(4):2.
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