What does it mean that semen is not liquefied?

Under normal circumstances, male semen is liquefied when it is discharged from the body, and it will solidify into jelly or clot in a short time. After 10 ~ 30 minutes, the semen will gradually liquefy into a liquid similar to water. This process is the liquefaction of semen, which is a normal physiological phenomenon. If the semen is still gelatinous after being discharged for more than 30 minutes, it belongs to liquefaction delay; If it does not liquefy for more than 60 minutes, it is a pathological state, which is called semen non-liquefaction.

Extended data; Causes of non-liquefaction and common diseases (for reference)

1. Prostatitis

① Inflammation: The secretion of semen liquefaction factors produced by prostate, such as proteolytic enzyme and fibrinolytic enzyme, is blocked, and the liquefaction factors are reduced, resulting in semen liquefaction. ② Urine irritation: Urine contains a variety of acid-base chemicals, which easily causes uric acid to flow back to the prostate and induce chronic prostatitis. Over time, it will also reduce the secretion of liquefying enzymes in the prostate, resulting in semen liquefaction.

2. seminal vesiculitis

The secretion of seminal vesicle is involved in the process of semen coagulation and liquefaction, and the coagulation factor produced by seminal vesicle causes semen coagulation. Once the seminal vesicle is inflamed, the secretion of the above factors will be hindered, resulting in an increase in coagulation factors and no liquefaction of semen.

3. Pathogenic microbial infection

If all kinds of pathogenic microorganisms, such as bacteria and protozoa invade the male reproductive tract, it is easy to cause a series of diseases, and semen liquefaction is one of them.

4. Lack of trace elements

Men's lack of trace elements, such as magnesium and zinc, can also lead to symptoms of semen liquefaction.

5. Anxiety, depression and fear

It is found that 50% of patients with non-liquefied semen are accompanied by symptoms such as anxiety, depression and excessive tension.